Pairwise Alignments
Query, 1010 a.a., diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) (RefSeq) from Shewanella loihica PV-4
Subject, 1247 a.a., Membrane-bound lytic murein transglycosylase F from Pseudomonas sp. RS175
Score = 438 bits (1127), Expect = e-126
Identities = 275/790 (34%), Positives = 423/790 (53%), Gaps = 31/790 (3%)
Query: 227 IKVNPRLCKMLKYSETELLNRTWTELTYFEDLKADMTQFQRMLKGEIDAYEMDKRFVAKD 286
++VN + + +++ +T TEL + QR+ G I EM F +
Sbjct: 461 LEVNKAFEEQIGLGAEDVVGQTATELNIWGIQGVGPGLLQRLQAGSIRNLEMP--FRRSN 518
Query: 287 GEIVYTHLTVACRRNHNMVDMVIAGLIDITEHKRADMAMRTSQERLALVLESSDLGMWDW 346
G+ V+T L A + + ++ + DI++ K+ ++ S+E+ A +S G+
Sbjct: 519 GQ-VFTGLISAEPFDLDTTPALVVVVRDISQLKQTQQQLQISEEKFAKAFHASPDGL--- 574
Query: 347 DIKSNET-----KRNPWCAKVLGCD----LERLNRDSRIWIDAIHPQDRMAVL--NSIDR 395
+ S ++ + N +++ G + ++R D IW++ + + +L + R
Sbjct: 575 -LLSRQSDGLLIEVNEGFSRITGFNSALSVDRSTLDLGIWVNLNERKQMLDLLQRDGFVR 633
Query: 396 HLKGETQKHYIEYRLISLSGEEHWILDTGKVVSRDRNGLPTRMCGVHSDITEQKKVQESL 455
+++ + RL +S I G M + DITE+ +QE L
Sbjct: 634 DFSCHIRRNDGQIRLCEVSSRPLPI------------GNEDCMLTIARDITERHLMQEKL 681
Query: 456 ELAASVYNNSSEAMSVQDHKGHIITINAAFTAITGYSQEEALTQNIRILQSSRTPRSQYD 515
+ AA+V+ +++E + + D + HI +N AFT ITGYS+ EAL R+L S + Y
Sbjct: 682 QQAATVFESTAEGVLITDTQQHISAVNRAFTEITGYSETEALGHTPRLLASGLHDSAFYA 741
Query: 516 EMNSAIRDTGYWQGELWIKNKSGEEYMVWLTINTIFDQHGQVYRRVALFSDITEKKEAEH 575
M + G+WQGE+ + K+GE Y WLTI+ + ++ Q+ VA+F+DI+ K A+
Sbjct: 742 AMWHQLTAEGHWQGEISNRRKNGELYPSWLTISAVRNRDQQITHFVAVFADISSLKHAQA 801
Query: 576 IIWKQANYDPLTGLPNRRMLLEYLNTEILRIDRNHSHFALMFLDLDFFKEVNDTLGHDMG 635
+ QA++DPLTGLPNR + L T + N A++FLDLD FK +ND+LGH +G
Sbjct: 802 KLDYQAHHDPLTGLPNRTLFESRLLTALNSQQENGGQGAVLFLDLDRFKHINDSLGHPVG 861
Query: 636 DLLLQETAKRLKGCIRESDVVARLGGDEFTVVLSGIDSPSGVERVAQSILERIAEPYSLG 695
DLLL+ A RL+ +R+ D VARLGGDEF ++L G+ PS E +A +L A P+ G
Sbjct: 862 DLLLKGIAVRLREQLRDIDTVARLGGDEFIILLPGLQQPSDAEHIAMKLLNCFAAPFQAG 921
Query: 696 DETAYISASIGITIYPDDATSIEGLLKHADQAMYAAKEQGRNRFHYFTPSMQEYARYRMA 755
+ +ISASIG ++YP D + L+K+AD AMY +K +GRNR +T + A R+A
Sbjct: 922 EHEFFISASIGTSLYPQDGCDVATLVKNADAAMYRSKAKGRNRVESYTRDLTAQASERVA 981
Query: 756 LIKDLRNAINRKEFELFYQPIVDMNKLGVYKAEALIRWVHPQRGLVSPGEFIPVAEETGL 815
L +LR AI R E L +QP + + + AEALIRW HP G V P FIP+AEE G+
Sbjct: 982 LEHELRRAIERSELSLSFQPKISLADNRLVGAEALIRWTHPTFGDVPPEHFIPLAEENGM 1041
Query: 816 INEIGNWVFEKAAQQSARWRTQHGVEIQISINKSPIQFRDEGDTFSDWLALLRHLELSSN 875
I +IG+WV E A +Q W + +S+N + Q R + + LLR L
Sbjct: 1042 ILQIGDWVLEHACRQLCEWNSSCESFGPLSVNLAGAQLR-QPNLLGRIEQLLREHHLKPG 1100
Query: 876 AICVEITEGLLLDASMGVTDKLLAYRDAGIQVSLDDFGTGYSSLAYLKKFDIDYLKIDQS 935
+ +EITE ++ + L + G+Q+++DDFGTGYSSL+YLK+ +D LKIDQS
Sbjct: 1101 LLQLEITENFIMSQAEEALTVLHQLKKLGVQLAIDDFGTGYSSLSYLKRLPLDILKIDQS 1160
Query: 936 FTRNLESDSDGVALCEAIIVMAHKLGIKVIAEGVETQFQHDILASAGCDFAQGYLYSKPV 995
F R L D VA+ AII + + +IAEGVET Q LA GC+ QGY+ S P+
Sbjct: 1161 FVRGLPDDPHDVAIVRAIIALGRSMQFSIIAEGVETLAQQQFLAEEGCEQIQGYIISLPL 1220
Query: 996 SLPEFERLYV 1005
EF ++
Sbjct: 1221 CAEEFAATFL 1230
Score = 49.7 bits (117), Expect = 1e-09
Identities = 54/249 (21%), Positives = 106/249 (42%), Gaps = 20/249 (8%)
Query: 260 ADMTQFQRMLKGEIDAYEM---DKRFVAKDGEIVYTHLTVACRRNHNMVDMVIAGLIDIT 316
A++++ Q G + Y D F G ++ + R + + IA +++
Sbjct: 244 AEVSEIQEKWIGNVRDYRQLWSDLLFYGLPGVLILVGILAVVIRINRRLSSEIARRVELE 303
Query: 317 EHKRADMAMRTSQERLALVLESSDLGMWDWDIKS-NETKRNPWCAKVLGCDLERLNRDSR 375
+ +R+S+ ++ES W+ + + +P +LG L
Sbjct: 304 QE------LRSSEYHYRGLVESLSAIAWEARVSDFTYSYVSPHAEDLLGYPLAHWLIPG- 356
Query: 376 IWIDAIHPQDRMAVLNSIDRHLKGETQKHYIEYRLISLSGEEHWILDTGKVVSRDRNGLP 435
W + IHP D + D+ + + H I+YR+I+ G W+ D +VS ++G
Sbjct: 357 FWRNIIHPADLIRAQTYCDQEVLAG-RDHCIDYRVITADGRCLWVRD---IVSLIQHGHE 412
Query: 436 TRMCGVHSDITEQKKVQESLELA----ASVYNNSSEAMSV-QDHKGHIITINAAFTAITG 490
M G+ DI+E K+ +E+L + ASV+ + + + + G ++ +N AF G
Sbjct: 413 PVMRGLMIDISEAKRTEEALRFSEQKFASVFRQCPDILVIARLMDGCLLEVNKAFEEQIG 472
Query: 491 YSQEEALTQ 499
E+ + Q
Sbjct: 473 LGAEDVVGQ 481
Score = 35.0 bits (79), Expect = 3e-05
Identities = 77/354 (21%), Positives = 155/354 (43%), Gaps = 47/354 (13%)
Query: 164 LVQIALPVMLIFPIVTALLGMMLARRLEVERDAKIQLQDDFIFRSQFNVGNMGIAITSV- 222
L+ LP +LI + A++ + + RRL E +++L+ + + S+++ + +++++
Sbjct: 267 LLFYGLPGVLILVGILAVV-IRINRRLSSEIARRVELEQE-LRSSEYHYRGLVESLSAIA 324
Query: 223 ------DQHWIKVNPRLCKMLKYSETE-LLNRTWTELTYFEDL-KADMTQFQRMLKGEID 274
D + V+P +L Y L+ W + + DL +A Q +L G
Sbjct: 325 WEARVSDFTYSYVSPHAEDLLGYPLAHWLIPGFWRNIIHPADLIRAQTYCDQEVLAGRDH 384
Query: 275 AYEMDKRFVAKDGEIVYTHLTVACRRNHNMVDMVIAGL-IDITEHKRADMAMRTSQERLA 333
+D R + DG ++ V+ ++ + + V+ GL IDI+E KR + A+R S+++ A
Sbjct: 385 C--IDYRVITADGRCLWVRDIVSLIQHGH--EPVMRGLMIDISEAKRTEEALRFSEQKFA 440
Query: 334 LVLESSD-----LGMWDWDI----KSNETKRNPWCAKVLGCDLERLNRDSRIW-IDAIHP 383
V + D + K+ E + V+G LN IW I + P
Sbjct: 441 SVFRQCPDILVIARLMDGCLLEVNKAFEEQIGLGAEDVVGQTATELN----IWGIQGVGP 496
Query: 384 QDRMAVLNSIDRHLKGETQKHYIEYRLISLSGEEHWILDTGKVVSRDRNGLPTRMCGVHS 443
+ R+L+ ++ + L E + LDT + V
Sbjct: 497 GLLQRLQAGSIRNLEMPFRRSNGQV-FTGLISAEPFDLDT-----------TPALVVVVR 544
Query: 444 DITEQKKVQESLELA----ASVYNNSSEAMSV-QDHKGHIITINAAFTAITGYS 492
DI++ K+ Q+ L+++ A ++ S + + + + G +I +N F+ ITG++
Sbjct: 545 DISQLKQTQQQLQISEEKFAKAFHASPDGLLLSRQSDGLLIEVNEGFSRITGFN 598
Score = 32.0 bits (71), Expect = 3e-04
Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 2/107 (1%)
Query: 216 GIAITSVDQHWIKVNPRLCKMLKYSETELLNRTWTELTYFEDLKADMTQFQRMLKGEIDA 275
G+ IT QH VN ++ YSETE L T L A L E
Sbjct: 694 GVLITDTQQHISAVNRAFTEITGYSETEALGHTPRLLASGLHDSAFYAAMWHQLTAE-GH 752
Query: 276 YEMDKRFVAKDGEIVYTHLTVACRRNHN-MVDMVIAGLIDITEHKRA 321
++ + K+GE+ + LT++ RN + + +A DI+ K A
Sbjct: 753 WQGEISNRRKNGELYPSWLTISAVRNRDQQITHFVAVFADISSLKHA 799