Pairwise Alignments
Query, 413 a.a., PE-PGRS family protein PE_PGRS39 from Mycobacterium tuberculosis H37Rv
Subject, 1901 a.a., PE-PGRS family protein PE_PGRS54 from Mycobacterium tuberculosis H37Rv
Score = 189 bits (480), Expect = 6e-52
Identities = 139/334 (41%), Positives = 161/334 (48%), Gaps = 49/334 (14%)
Query: 1 MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQ 60
MS V AP + A+AG+L +GS++ AANA+AA+ T VLAAG D+VSA IAALFG
Sbjct: 1 MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSARIAALFGGFGL 60
Query: 61 AYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQ---------D 111
YQAISAQ A +H RFVQ L GA AYA AEAA A Q GV++ Q D
Sbjct: 61 EYQAISAQVAAYHQRFVQALSTGAGAYASAEAAAA--EQIVLGVINAPTQALLGRPLIGD 118
Query: 112 RTGGTGTGQSRGAGGF----GGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVA 167
T G + GAGG GG G AG G GGP G + G G G + G G A
Sbjct: 119 GANATTPGGAGGAGGLLFGNGGAGAAGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGA 178
Query: 168 GAAHG--------SGVSASHG--SGATGAAGVADPGGSGAGVGSAAGNGTGAG------- 210
G A G GV + G GA G G+ GG GVG A G GAG
Sbjct: 179 GGAGGWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLF 238
Query: 211 SADAVGGAGT--GRDIVGSVRGDGGVG--------MASGDGGLSTGAAGASAEGGLMPGF 260
A GGAGT G G G GGVG +G G GA GA ++GG + G
Sbjct: 239 GAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSDGGALGGT 298
Query: 261 GGAPWVGGHWGLGGE-------GHSGAIGGVGEQ 287
GG GG G GG G G +GG G Q
Sbjct: 299 GGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQ 332
Score = 128 bits (321), Expect = 2e-33
Identities = 121/396 (30%), Positives = 149/396 (37%), Gaps = 25/396 (6%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL 71
A+ G G T A A A AG GG +AG A + G Q + A
Sbjct: 460 ASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTGGQGGAGGAGSAGT 519
Query: 72 FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTG-TGQSRGAGGFGGV 130
D G A A A G + +GG G TG + GAGG GGV
Sbjct: 520 --DATATGATGGTGFSGGAGGAGG-----AGGNTGVGGTNGSGGQGGTGGAGGAGGAGGV 572
Query: 131 GQ-----AGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATG 185
G GG G GG G G G Q G+ G T+G+ G G G + G+GA
Sbjct: 573 GADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADN 632
Query: 186 AAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAG-----TGRDIVGSVRGDGGVGMASGD 240
G+ GG+G G G AAG G GAG A GG G G +G G GGVG A G
Sbjct: 633 PTGIGGAGGTG-GTGGAAGAG-GAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGA 690
Query: 241 GGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSP 300
G + + A+ G G GG GG+ G+GG SG GG G + A
Sbjct: 691 GAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGSGADN 750
Query: 301 ATTSAVAAESGST-PATKAQAMHATTNPGN----AAHQGNPADPGNSARRADGGRDEQLL 355
T + A +G T A A T G G+ G R DGG L
Sbjct: 751 PTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGL 810
Query: 356 LLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASG 391
L L+ G + G G+ A G +G
Sbjct: 811 GLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNG 846
Score = 117 bits (292), Expect = 4e-30
Identities = 100/284 (35%), Positives = 116/284 (40%), Gaps = 47/284 (16%)
Query: 113 TGGTG-TGQSRGAGGFG---------GVGQAGGKGWDGGP--------IGNGQVGEQHGA 154
+GGTG TG G GG G+G AGG+G DGG GNG G Q G
Sbjct: 1587 SGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQ 1646
Query: 155 GQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSG--------AGVGSAAGNG 206
G +G G G+ GA G + G G G GVA GG+G G+G A GN
Sbjct: 1647 GGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNA 1706
Query: 207 ------------TGAGSADAVGGAGTGRD--IVGSVRGDGGVGMASGDGGL-STGAAGAS 251
G G A GGAG D I G G GG G G GGL STG A A+
Sbjct: 1707 GFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAA 1766
Query: 252 AEGGLMPGFGGAPWVGGHWGLGGEGHSGAI---GGVGEQVAPAVATAPAVSP--ATTSAV 306
+ G G GGA GG GLGG G +G GG+G A +P + T
Sbjct: 1767 SGDGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGT 1826
Query: 307 AAESGSTPA-TKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
+ G A + N GN GN D GN A GG
Sbjct: 1827 GGDGGDAGAGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGG 1870
Score = 115 bits (288), Expect = 1e-29
Identities = 116/359 (32%), Positives = 140/359 (38%), Gaps = 37/359 (10%)
Query: 13 ASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQA-ISAQAAL 71
A A A ST A GV GG+ ++ GI GA Q
Sbjct: 396 AGAAGADAPASTGLTGGTGFAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGGAGGMGGS 455
Query: 72 FHDRFVQILQEGAAA-----YAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGG 126
D I +G A A A GVV + GGTG GQ GAGG
Sbjct: 456 GADNASGIGADGGAGGTGGNAGAGGAGGAAGTGGTGGVVGAAGKAGIGGTG-GQG-GAGG 513
Query: 127 FG-------------GVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGS 173
G G G +GG G GG GN VG +G+G G T G G AG A G
Sbjct: 514 AGSAGTDATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGT-GGAGGAGGAGGV 572
Query: 174 GVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAG--TGRDIVGSVRGD 231
G G G TG G G GAG G +GAG + GGAG G+ G G
Sbjct: 573 GADNPTGIGGTGGTG----GKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGGAGGAGGA 628
Query: 232 G-----GVGMASGDGGLSTGAAGASAEGGLM--PGFGGAPWVGGHWGLGGEGHSGAIGGV 284
G G+G A G GG + GAAGA GG + G GGA G+ G+GG G +G +GG
Sbjct: 629 GADNPTGIGGAGGTGG-TGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGA 687
Query: 285 GEQVAPAVATAPAVSPA-TTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNS 342
G A A A + A A E G+ + + + G A +G G S
Sbjct: 688 GGAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGAGGS 746
Score = 113 bits (282), Expect = 6e-29
Identities = 103/338 (30%), Positives = 119/338 (35%), Gaps = 36/338 (10%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL 71
A G L G A GV GG G+A L GA A Q SA
Sbjct: 320 AGGQGGLGGAGGQGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSA---- 375
Query: 72 FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVG 131
G AA A+ G + G G G GG G
Sbjct: 376 -----------GGAAGAVGVG----------GTGGQGGAGGAGAAGADAPASTGLTGGTG 414
Query: 132 QAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVAD 191
AGG G GG GN G +G+G G T G G AG GSG + G GA G AG
Sbjct: 415 FAGGAGGVGGQGGNAIAGGINGSGGAGGTGGQGG-AGGMGGSGADNASGIGADGGAGGTG 473
Query: 192 PGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGAS 251
G G AAG G G A G AG +G G GG G +G G A GA+
Sbjct: 474 GNAGAGGAGGAAGTGGTGGVVGAAGKAG-----IGGTGGQGGAG-GAGSAGTDATATGAT 527
Query: 252 AEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESG 311
G G GGA GG+ G+GG SG GG G A A V + + G
Sbjct: 528 GGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGTGG--AGGAGGAGGVGADNPTGIGGTGG 585
Query: 312 STPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
+ K A A G++ G G GG
Sbjct: 586 T--GGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQGG 621
Score = 110 bits (275), Expect = 4e-28
Identities = 113/366 (30%), Positives = 134/366 (36%), Gaps = 59/366 (16%)
Query: 16 GELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAALFHDR 75
G G T AA A A G GG S G A + G + A
Sbjct: 637 GGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGA------ 690
Query: 76 FVQILQEGAAAYAMAEAANALPLQK-AQGVVSELAQDRTGGT-GTGQSRGAGGFGGVGQA 133
GAAA A + A A G GGT G+G + GAGG GG G A
Sbjct: 691 -------GAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGAGGKGGTGGA 743
Query: 134 GGKGWD--------GGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATG 185
GG G D GG G G GAG T G GV GA +G+ + G G G
Sbjct: 744 GGSGADNPTGAGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDG 803
Query: 186 AAGVAD--------------PGGSGA--------GVGSAAGNGTGAGSADAVGGAGTGRD 223
G + GG+G G G A GNG G G A G AG G +
Sbjct: 804 GDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNG-GDGGDGATGAAGLGDN 862
Query: 224 IVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGG 283
G V GDGG G A+G+GG + A A G G GG GG G G +G GG
Sbjct: 863 --GGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGG 920
Query: 284 VGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSA 343
G Q + A+T+++ A G A T G A G G+
Sbjct: 921 AGGQGGQG-----GLGGASTTSINANGG------AGGNGGTGGKGGAGGAGTLGVGGSGG 969
Query: 344 RRADGG 349
DGG
Sbjct: 970 TGGDGG 975
Score = 108 bits (271), Expect = 1e-27
Identities = 87/256 (33%), Positives = 101/256 (39%), Gaps = 31/256 (12%)
Query: 113 TGGTG-TGQSRGAGGFG---------GVGQAGGKGWDGGP--------IGNGQVGEQHGA 154
+GGTG TG G GG G+G AGG+G DGG GNG G Q G
Sbjct: 1382 SGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQ 1441
Query: 155 GQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADA 214
G +G G G+ GA G + G G G GVA GG+G G G G G
Sbjct: 1442 GGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAG-------GQG-GDGGQGG 1493
Query: 215 VGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGG 274
+GGAG V GDGG+G G GG G AGA + + G GGA GG G GG
Sbjct: 1494 IGGAGGNAGFGAGVPGDGGIGGTGGAGG--AGGAGADGDPSIDGGQGGAGGHGGQGGKGG 1551
Query: 275 EGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQA-MHATTNPGNAAHQ 333
+G A + SG T T A + N G A
Sbjct: 1552 LNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTA-- 1609
Query: 334 GNPADPGNSARRADGG 349
GN G R DGG
Sbjct: 1610 GNAGIGGAGGRGGDGG 1625
Score = 108 bits (269), Expect = 2e-27
Identities = 89/245 (36%), Positives = 104/245 (42%), Gaps = 23/245 (9%)
Query: 114 GGTGTGQSRGAGGFG--GVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAG--- 168
G GTG GAGG G GVG +GG G DGG G+G G GA GN G G
Sbjct: 946 GNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGRGGDGG 1005
Query: 169 -AAHGSGVSASH---GSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDI 224
A G G+ S G G G AG + G G G A GNG G G A G AG G +
Sbjct: 1006 DGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNG-GDGGDGATGAAGLGDN- 1063
Query: 225 VGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGV 284
G V GDGG G A+G+GG + A A G G GG GG G G +G GG
Sbjct: 1064 -GGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGA 1122
Query: 285 GEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSAR 344
G Q + A+T+++ A G A T G A G G+
Sbjct: 1123 GGQGGQG-----GLGGASTTSINANGG------AGGNGGTGGKGGAGGAGTLGVGGSGGT 1171
Query: 345 RADGG 349
DGG
Sbjct: 1172 GGDGG 1176
Score = 106 bits (264), Expect = 7e-27
Identities = 96/301 (31%), Positives = 112/301 (37%), Gaps = 43/301 (14%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGS 173
G GTG + G G GGVG GGKG GG G G G AGQL S G G G
Sbjct: 331 GQGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGG--AAGQLFSAGGAAGAVGVGGTG 388
Query: 174 GVSASHGSGATGA---------AGVADPGGSGAGVGSAAGNG-----TGAGSADAVGG-- 217
G + G+GA GA G GG+G GVG GN G+G A GG
Sbjct: 389 GQGGAGGAGAAGADAPASTGLTGGTGFAGGAG-GVGGQGGNAIAGGINGSGGAGGTGGQG 447
Query: 218 -----AGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGL 272
G+G D + DGG G G+ G + GA GA+ GG GG G G+
Sbjct: 448 GAGGMGGSGADNASGIGADGGAGGTGGNAG-AGGAGGAAGTGGT----GGVVGAAGKAGI 502
Query: 273 GGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAH 332
GG G G GG G A AT T G+ A A +
Sbjct: 503 GGTGGQGGAGGAGSAGTDATAT------GATGGTGFSGGAGGAGGAGGNTGVGGTNGSGG 556
Query: 333 QGNPADPGNSARRADGGRDEQLLLLPLTSLRGLRHTLKK--LSGLRARNGLLTASGDNAS 390
QG G + G D T + G T K G + G A G N S
Sbjct: 557 QGGTGGAGGAGGAGGVGADNP------TGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGS 610
Query: 391 G 391
G
Sbjct: 611 G 611
Score = 106 bits (264), Expect = 7e-27
Identities = 83/235 (35%), Positives = 99/235 (42%), Gaps = 31/235 (13%)
Query: 81 QEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDG 140
Q G A A QG + + G G G GG GG G AGG G DG
Sbjct: 1470 QNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADG 1529
Query: 141 GPI------GNGQVGEQHGAGQLGST--------DGNPGVAGAAHGSG------VSASHG 180
P G G G Q G G L ST DG G AG A G+G + S G
Sbjct: 1530 DPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGG 1589
Query: 181 SGAT----GAAGVADPGGS--GAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGGV 234
+G T G G+A+ GG+ AG+G A G G G+ D+ + G G G GGV
Sbjct: 1590 TGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGGV 1649
Query: 235 GMASGDGGLSTGAAGASAEGGL----MPGFGGAPWVGGHWGLGGEGHSGAIGGVG 285
G +G GG++ GA G GG G G GG G GG+G G IGG G
Sbjct: 1650 GGNAGAGGIN-GAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAG 1703
Score = 104 bits (260), Expect = 2e-26
Identities = 99/281 (35%), Positives = 122/281 (43%), Gaps = 47/281 (16%)
Query: 113 TGGTG-TGQSRGAG-----GFGGVGQAG------GKGWDGGPIGNGQVGEQHGA---GQL 157
TGG G G + GAG G GG G G G G GG IG G G G+ +
Sbjct: 616 TGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGI 675
Query: 158 GSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGG--SGAGVGSAAGNGTGAGSADAV 215
G T G GV GA G+G +A+ GS ATG AG A G GAG S G G+G A
Sbjct: 676 GGTGGTGGVGGAG-GAGAAAAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSGGAGGA 734
Query: 216 GG-------AGTGRDI---VGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPW 265
GG G+G D G G GG G A+G GG + GA G GG++ G G+
Sbjct: 735 GGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAGAGG-AGGATGTGGTGGVV-GATGSAG 792
Query: 266 VGGHWGLGGEGHSGAIG-GV----------GEQVAPAVATAPAVSPATTSAVAAESGSTP 314
+GG G GG+G GA G G+ G+ A A A ++ A + G
Sbjct: 793 IGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDG 852
Query: 315 ATKAQAM------HATTNPGNAAHQGNPADPGNSARRADGG 349
AT A + G AA G A G +A+ DGG
Sbjct: 853 ATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGG 893
Score = 104 bits (260), Expect = 2e-26
Identities = 80/247 (32%), Positives = 93/247 (37%), Gaps = 10/247 (4%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGP-------IG-NGQVGEQHGAGQLGSTDGNPG 165
G G G S GAGG G G AGG G DGG +G NG VG GAG GN G
Sbjct: 1024 GQGGAGGSAGAGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAG 1083
Query: 166 VA--GAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRD 223
V A G + + G+G G AG A G G A G G G A +
Sbjct: 1084 VGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANG 1143
Query: 224 IVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGG 283
G G GG G A G G L G +G + G G GG GG G G G +G +GG
Sbjct: 1144 GAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGKAGGGGNGGVGG 1203
Query: 284 VGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSA 343
G + A + + GS A G A G PA
Sbjct: 1204 DGGEGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGP 1263
Query: 344 RRADGGR 350
DGG+
Sbjct: 1264 DGGDGGQ 1270
Score = 102 bits (255), Expect = 8e-26
Identities = 77/199 (38%), Positives = 91/199 (45%), Gaps = 28/199 (14%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKG---WDGGPIGNGQVGEQHGAGQLGST--------DG 162
G G G G GG GG G AG G DGG G G G Q G G L ST DG
Sbjct: 1301 GVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDG 1360
Query: 163 NPGVAGAAHGSG------VSASHGSGAT----GAAGVADPGGS--GAGVGSAAGNGTGAG 210
G AG A G+G + S G+G T G G+A+ GG+ AG+G A G G G
Sbjct: 1361 GNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGG 1420
Query: 211 SADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGL----MPGFGGAPWV 266
+ D+ + G G G GGVG +G GG++ GA G GG G G
Sbjct: 1421 AGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGIN-GAGGTGGTGGAGGDGQNGTTGVASE 1479
Query: 267 GGHWGLGGEGHSGAIGGVG 285
GG G GG+G G IGG G
Sbjct: 1480 GGAGGQGGDGGQGGIGGAG 1498
Score = 102 bits (254), Expect = 1e-25
Identities = 114/372 (30%), Positives = 129/372 (34%), Gaps = 49/372 (13%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQA-A 70
A AG G A A A T G G SAGI G S
Sbjct: 754 AGFAGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLG 813
Query: 71 LFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGV 130
L Q Q GA A A N A G + TG G G + G GG GG
Sbjct: 814 LSGFDGGQGGQGGAGGSAGAGGINGAG--GAGGNGGDGGDGATGAAGLGDNGGVGGDGGA 871
Query: 131 GQAGGKGW-----------DGGPIGNGQ---VGEQHGAGQ---------LGSTDGNPGVA 167
G A G G DGG GNG G GAG G G G+
Sbjct: 872 GGAAGNGGNAGVGLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLG 931
Query: 168 GAAHGS--------GVSASHGSGATGAAGVADPGGSG--AGVGSAAGNGTGAGSADAVGG 217
GA+ S G + G G G AG GGSG G G AG+G G G A G
Sbjct: 932 GASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAGK 991
Query: 218 AGTGRDIVGSVRGDGGVGMASGDG--GLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGE 275
AG G G+GG G GDG GL G +G G G GG+ GG G GG
Sbjct: 992 AGGG--------GNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGA 1043
Query: 276 GHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGN 335
G +G GG G A + V + AA +G + A G AA G
Sbjct: 1044 GGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGV---GLTAKAGDGGAAGNGG 1100
Query: 336 PADPGNSARRAD 347
G + D
Sbjct: 1101 NGGAGGAGGAGD 1112
Score = 102 bits (254), Expect = 1e-25
Identities = 74/181 (40%), Positives = 83/181 (45%), Gaps = 12/181 (6%)
Query: 113 TGGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLG--STDGNPGVAGAA 170
T G G + G GG GG G AGG G + G G G Q G G LG ST GA
Sbjct: 1087 TAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINANGGAG 1146
Query: 171 HGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRG 230
G G+G G GV GG+G G G AG+G G G A G AG G + G V G
Sbjct: 1147 GNGGTGGKGGAGGAGTLGVGGSGGTG-GDGGDAGSGGGGGFGGAAGKAGGGGN--GGVGG 1203
Query: 231 DGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAP 290
DGG G GL G +G G G GG+ GG G GG G +G GG G AP
Sbjct: 1204 DGG----EGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDG---AP 1256
Query: 291 A 291
A
Sbjct: 1257 A 1257
Score = 100 bits (250), Expect = 3e-25
Identities = 98/291 (33%), Positives = 117/291 (40%), Gaps = 37/291 (12%)
Query: 113 TGGTGT--GQSRGAGGFGGVGQAGG-KGWDGGPI-------GNGQVGEQHGAGQLGSTDG 162
TGG G G G GG GGVG AGG G GG G G G G G G T G
Sbjct: 201 TGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAGGAGTDGGPGATGGTGG 260
Query: 163 NPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGR 222
+ GV G G A G+G GA G GG+G+ G+ G G G+ A G G G
Sbjct: 261 HGGVGG---DGGWLAPGGAG--GAGGQGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGA 315
Query: 223 DIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIG 282
++G+ G GG+G A G GG TG AG G++ G GG GG G+GG G G
Sbjct: 316 LLLGA-GGQGGLGGAGGQGG--TGGAGGD---GVLGGVGG---TGGKGGVGGVAGLGGAG 366
Query: 283 GVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNS 342
G Q+ A A AV T +G A A A +T G G G
Sbjct: 367 GAAGQLFSAGGAAGAVGVGGTGGQGG-AGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQ 425
Query: 343 ARRADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSG 393
A G + G T G G+ + DNASG G
Sbjct: 426 GGNAIAG--------GINGSGGAGGT----GGQGGAGGMGGSGADNASGIG 464
Score = 100 bits (249), Expect = 4e-25
Identities = 75/192 (39%), Positives = 88/192 (45%), Gaps = 23/192 (11%)
Query: 114 GGTGTGQSRGAGGFG--GVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAH 171
G GTG GAGG G GVG +GG G DGG G+G G G G G G AG
Sbjct: 1147 GNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSG------GGGGFG---GAAGKAGGGG 1197
Query: 172 GSGVSASHGSGATGAA-GVADPGGSGAGVGSAAGNGTGAGSADAVGGA----GTGRD--- 223
GV G GA+G G++ G G G A G+ GAG + GGA G G D
Sbjct: 1198 NGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSA-GAGGINGAGGAGGTGGAGGDGAP 1256
Query: 224 ---IVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGA 280
I G GDGG G GDGG + AG +GG G V G G+GG G +G
Sbjct: 1257 ATLIGGPDGGDGGQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGG 1316
Query: 281 IGGVGEQVAPAV 292
GG G P++
Sbjct: 1317 AGGAGADGDPSI 1328
Score = 99.0 bits (245), Expect = 1e-24
Identities = 103/338 (30%), Positives = 126/338 (37%), Gaps = 85/338 (25%)
Query: 9 NVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGD--DVSAGIAALFGARAQAYQAIS 66
N A G +G A A T G AGGD + + G+A+ GA Q
Sbjct: 1432 NGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDG-- 1489
Query: 67 AQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGG 126
+G A A + G+ GGTG GAGG
Sbjct: 1490 --------------GQGGIGGAGGNAGFGAGVPGDGGI---------GGTG-----GAGG 1521
Query: 127 FGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGST--------DGNPGVAGAAHGSG---- 174
GG G G DGG G G G Q G G L ST DG G AG A G+G
Sbjct: 1522 AGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGD 1581
Query: 175 --VSASHGSGATGA----AGVADPGGSG--AGVGSAAGNGTGAGSADA----------VG 216
+ S G+G TG G+A+ GG+ AG+G A G G G+ D+ G
Sbjct: 1582 GFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAG 1641
Query: 217 GAG--------TGRDIVGSVRGDGGVGMASGDGGLST-------GAAGASAEGGLMPGFG 261
G G G + G GG G A GDG T GA G +GG G G
Sbjct: 1642 GQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGG-QGGIG 1700
Query: 262 GA-------PWVGGHWGLGGEGHSGAIGGVGEQVAPAV 292
GA V G G+GG G +G GG G P++
Sbjct: 1701 GAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSI 1738
Score = 99.0 bits (245), Expect = 1e-24
Identities = 81/214 (37%), Positives = 92/214 (42%), Gaps = 14/214 (6%)
Query: 81 QEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDG 140
Q G A A QG + + G G G GG GG G AGG G DG
Sbjct: 1675 QNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADG 1734
Query: 141 GPIGNGQVGEQHGAGQLGSTDG--NPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAG 198
P +G G G G G G + G+A AA G G + G+G G G A G G G
Sbjct: 1735 DPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDG--GNGGAGGAGGNGGAGGLGGGGG 1792
Query: 199 VGSAAGN-----GTGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGA--AGAS 251
G GN G G G A GG TG G+ GDGG A G+GG +TG G
Sbjct: 1793 TGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGT-GGDGGDAGAGGNGGSATGVGNGGNG 1851
Query: 252 AEGGL-MPGFGGAP-WVGGHWGLGGEGHSGAIGG 283
+GG G GAP GG G GG G SGA GG
Sbjct: 1852 GDGGNGGDGGNGAPGGFGGGAGAGGLGGSGAGGG 1885
Score = 97.8 bits (242), Expect = 2e-24
Identities = 71/194 (36%), Positives = 87/194 (44%), Gaps = 21/194 (10%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGS 173
G TG + A G GG G AGG G +GG G+G +G G+G G T G+ GV G A+
Sbjct: 1346 GLNSTGLASAASGDGGNGGAGGAGGNGGD-GDGFIG---GSGGTGGTGGDAGVGGLANTG 1401
Query: 174 GVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVG-GAGTGRDIVGSVRGDG 232
G + + G G G G D G +G S GNG G G G G + G G
Sbjct: 1402 GTAGNAGIGGAGGRG-GDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTG 1460
Query: 233 GVGMASGDGGLST-------GAAGASAEGGLMPGFGGA-------PWVGGHWGLGGEGHS 278
G G A GDG T GA G +GG G GGA V G G+GG G +
Sbjct: 1461 GTGGAGGDGQNGTTGVASEGGAGGQGGDGG-QGGIGGAGGNAGFGAGVPGDGGIGGTGGA 1519
Query: 279 GAIGGVGEQVAPAV 292
G GG G P++
Sbjct: 1520 GGAGGAGADGDPSI 1533
Score = 95.9 bits (237), Expect = 9e-24
Identities = 79/234 (33%), Positives = 95/234 (40%), Gaps = 20/234 (8%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAA--- 170
G G G GAGG GG G AGG G IG G G G G +G GN G
Sbjct: 1231 GSAGAGGINGAGGAGGTGGAGGDGAPATLIG-GPDGGDGGQGGIGGDGGNAGFGAGVPGD 1289
Query: 171 HGSGVSASHGSGATGAAGVADPGGS-GAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVR 229
G G +A G+G G G+ GG+ GAG A G+ + G GG G G+ G +
Sbjct: 1290 GGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHG-GQGGKGGLN 1348
Query: 230 GDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVA 289
G ASGDGG + GA GA GG GF +GG G GG G +GG+
Sbjct: 1349 STGLASAASGDGG-NGGAGGAGGNGGDGDGF-----IGGSGGTGGTGGDAGVGGLAN--- 1399
Query: 290 PAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSA 343
T A G A + A+ N G A QG G +A
Sbjct: 1400 ----TGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGN-GFAGGQGGQGGVGGNA 1448
Score = 95.5 bits (236), Expect = 1e-23
Identities = 82/256 (32%), Positives = 97/256 (37%), Gaps = 47/256 (18%)
Query: 106 SELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGG---PIGNGQVGEQHGAGQLGSTDG 162
+EL G G G G G GG G GG G DGG P G G G Q GAG GS G
Sbjct: 234 AELLFGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQGGAGGAGSDGG 293
Query: 163 NPGVAGAAHGSGVSASHGS------GATGAAGVADPGGSGAGVGSAAGNGT--------- 207
G G G+G + G GA G G+ GG G G G A G+G
Sbjct: 294 ALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQG-GTGGAGGDGVLGGVGGTGG 352
Query: 208 --GAGSADAVGGAG------------TGRDIVGSVRGDGGVGMA-------------SGD 240
G G +GGAG G VG G GG G A +G
Sbjct: 353 KGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGVGGTGGQGGAGGAGAAGADAPASTGLTGG 412
Query: 241 GGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSP 300
G + GA G +GG GG GG G GG+G +G +GG G A +
Sbjct: 413 TGFAGGAGGVGGQGGNAIA-GGINGSGGAGGTGGQGGAGGMGGSGADNASGIGADGGAGG 471
Query: 301 ATTSAVAAESGSTPAT 316
+A A +G T
Sbjct: 472 TGGNAGAGGAGGAAGT 487
Score = 94.0 bits (232), Expect = 4e-23
Identities = 86/265 (32%), Positives = 104/265 (39%), Gaps = 42/265 (15%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGW--------DGGPIGNGQVGEQHGAGQLGST----- 160
G G G GAGG GG G AGG G +GG G G G Q G G G
Sbjct: 1446 GNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGA 1505
Query: 161 ----DGNPGVAGAAHGSGVSASHG-----SGATGAAGVADPGGSG----AGVGSAA-GNG 206
DG G G A G+G + + G G GA G GG G G+ SAA G+G
Sbjct: 1506 GVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDG 1565
Query: 207 TGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGL-STGAAGASAEGGLMPGFGGAPW 265
G+ A G G G +G G GG G +G GGL +TG +A G GGA
Sbjct: 1566 GNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNA------GIGGA-- 1617
Query: 266 VGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATT 325
GG G GG G SGA+ G A V + +G T T
Sbjct: 1618 -GGRGGDGGAGDSGALSQDGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAG----- 1671
Query: 326 NPGNAAHQGNPADPGNSARRADGGR 350
G G ++ G + DGG+
Sbjct: 1672 GDGQNGTTGVASEGGAGGQGGDGGQ 1696
Score = 89.7 bits (221), Expect = 7e-22
Identities = 73/221 (33%), Positives = 88/221 (39%), Gaps = 26/221 (11%)
Query: 110 QDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGST--DGNPGVA 167
Q GG G GAG G G G G+ G G+G +G GAG G DG+P +
Sbjct: 1270 QGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSID 1329
Query: 168 GAAHGSGVSASHGS----GATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRD 223
G G+G G +TG A A G G G A GNG G G G GTG
Sbjct: 1330 GGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNG-GDGDGFIGGSGGTG-- 1386
Query: 224 IVGSVRGDGGVGMASGDGGLS-----TGAAGASAEGGL-------MPGFGGAPWVGGHWG 271
GD GVG + GG + GA G +GG G G A GG G
Sbjct: 1387 ---GTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGFAGGQGGQGG 1443
Query: 272 LGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGS 312
+GG +G I G G A T+ VA+E G+
Sbjct: 1444 VGGNAGAGGINGAGG--TGGTGGAGGDGQNGTTGVASEGGA 1482
Score = 88.2 bits (217), Expect = 2e-21
Identities = 85/286 (29%), Positives = 103/286 (36%), Gaps = 48/286 (16%)
Query: 9 NVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGD--DVSAGIAALFGARAQAYQAIS 66
N A G +G A A T G AGGD + + G+A+ GA Q
Sbjct: 1637 NGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDG-- 1694
Query: 67 AQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGT-------G 119
+G A A + G+ GG G G
Sbjct: 1695 --------------GQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDG 1740
Query: 120 QSRGAGGFGGVGQAGG---------------KGWDGGPIGNGQVGEQHGAGQLGSTDGNP 164
GAGG GG G GG G GG GNG G G G G T+GN
Sbjct: 1741 GQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGAGGLGGGGGTGGTNGNG 1800
Query: 165 GVAGAAHGSGVSASHGSGATGAAGVADPGGSG--AGVGSAAGNGTGAGSADAVGGAGTGR 222
G+ G G+G + G TG +G GG G AG G G+ TG G+ G G G
Sbjct: 1801 GLGGGG-GNGGAGGAGGTPTG-SGTEGTGGDGGDAGAGGNGGSATGVGNGGNGGDGGNGG 1858
Query: 223 DIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGG 268
D G GG G +G GGL AG +G G GG+P G
Sbjct: 1859 D--GGNGAPGGFGGGAGAGGLGGSGAGGGTDGD--DGNGGSPGTDG 1900