Pairwise Alignments
Query, 413 a.a., PE-PGRS family protein PE_PGRS39 from Mycobacterium tuberculosis H37Rv
Subject, 731 a.a., PE-PGRS family protein PE_PGRS52 from Mycobacterium tuberculosis H37Rv
Score = 177 bits (450), Expect = 7e-49
Identities = 151/410 (36%), Positives = 176/410 (42%), Gaps = 64/410 (15%)
Query: 1 MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQ 60
MS V A P +LAA+A +LA I S + AA AAAAAPT V AAG D+VS I+ALFG AQ
Sbjct: 1 MSFVIANPEMLAAAATDLAGIRSAISAATAAAAAPTIQVAAAGADEVSLAISALFGQHAQ 60
Query: 61 AYQAISAQAALFHDRFVQILQEGAAAYAMAEA-------ANAL--PLQKAQGVVSELAQD 111
AYQA+SAQA +FHD+FVQ L G YA AE+ NA+ P Q G L D
Sbjct: 61 AYQALSAQATIFHDQFVQALTSGGNLYAAAESHTVEQMVLNAINAPTQTLFG--RPLIGD 118
Query: 112 RTGGTG---TGQSRGA----GGFG----GVGQAGGKGWDGGPIGNGQVGEQHGAGQLGST 160
GT GQ+ G GG G G AGG G G IGNG G GAG G
Sbjct: 119 GANGTAENPDGQNGGLLFGNGGNGFTQTTAGVAGGNGGSAGLIGNGGAGGGGGAGAAGGL 178
Query: 161 DGN----------PGVAGAAHGSGVSASHGS--------GATGAAGVADPGGSGAGVGSA 202
GN G+ GA G+G G G GA G GG G G A
Sbjct: 179 GGNGGWLYGNGGAGGIGGAGTGTGGHGGAGGAGGRAWLWGTGGAGGAGGDGGWLFGDGGA 238
Query: 203 AGNGTGAGS-----ADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLST---------GAA 248
G G GS +VGGAG G + G GG G G GG +T GA
Sbjct: 239 GGTGGNGGSGFNSLTSSVGGAGGAGGHAG-LFGAGGTGGTGGIGGQNTETGPAASNGGAG 297
Query: 249 GASAEGGLMPGFGGAPWVGGHWG---------LGGEGHSGAIGGVGEQVAPAVATAPAVS 299
GA GG + G GGA GG G GG G +G GG + + A
Sbjct: 298 GAGGGGGYLVGDGGAGGTGGAGGKNSSGGATLTGGTGGTGGAGGAAGWLYGSGGAGGAGG 357
Query: 300 PATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
+ +G T T GN G + GN+ GG
Sbjct: 358 AGGLNNAGGATGGTGGTGGAGGSGAWLYGNGGAAGAGGNGGNNTSAGTGG 407
Score = 94.7 bits (234), Expect = 8e-24
Identities = 83/274 (30%), Positives = 103/274 (37%), Gaps = 57/274 (20%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAG--QLGST-DGNPGVAGAA 170
G G G + + G GGVG +GG G + G IG G G GAG Q G +G G G A
Sbjct: 392 GAGGNGGNNTSAGTGGVGASGGTGGNAGLIGAGGHGGAGGAGGNQTGGVGNGGAGGNGGA 451
Query: 171 HGSG--VSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRD----- 223
G+G + + G G G AG A+ G G AAG+G GSA +G G G D
Sbjct: 452 GGAGGQLYGNGGDGGNGGAGGANIAGGNGSDGGAAGHGGAGGSARLIGAGGHGGDGGAGG 511
Query: 224 -----IVGSVRGDGGVGMASGDGGLSTGAAGASAEGGL---------------------- 256
++ G GG G G+GGL +G AGA GG
Sbjct: 512 NTAGRRADAIAGTGGDGGNGGNGGLLSGNAGAGGHGGAGGSSTATTTTGTPPTGATGGNG 571
Query: 257 -MPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPA 315
G GG G G+GG G +G GG + VA GST
Sbjct: 572 GNGGAGGTAGFTGSGGIGGNGGAGGTGG-------------------NAGVALSVGSTGG 612
Query: 316 TKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
G + GN G A +GG
Sbjct: 613 LGGNGGSGGLGGGGGSLFGNGGAGGVGATGGNGG 646
Score = 94.0 bits (232), Expect = 1e-23
Identities = 66/171 (38%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Query: 117 GTGQSRGAGGFGGV--GQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSG 174
GTG G GG GG+ G AG G GG G+ G G+T GN G GA +G
Sbjct: 523 GTGGDGGNGGNGGLLSGNAGAGG-HGGAGGSSTATTTTGTPPTGATGGNGGNGGAGGTAG 581
Query: 175 VSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGGV 234
+ S G G G AG G AGV + G+ G G GG G G + G GGV
Sbjct: 582 FTGSGGIGGNGGAGGT---GGNAGVALSVGSTGGLGGNGGSGGLGGGGGSLFGNGGAGGV 638
Query: 235 GMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVG 285
G G+GG G A GG G G A + G G GG G SG GG G
Sbjct: 639 GATGGNGGSGIGPASVGGNGG-KGGVGAAGGLAGQIGNGGSGGSGGAGGNG 688
Score = 91.3 bits (225), Expect = 9e-23
Identities = 83/249 (33%), Positives = 100/249 (40%), Gaps = 27/249 (10%)
Query: 113 TGGTGTGQSRGA----GGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAG 168
TGG G S G GG GG G AGG G G+G G GAG L + G G G
Sbjct: 315 TGGAGGKNSSGGATLTGGTGGTGGAGGAA--GWLYGSGGAGGAGGAGGLNNAGGATGGTG 372
Query: 169 AAHGSGVSASHGSGATGAAGVADPGGSG-----AGVGSAAGNGTGAG--SADAVGGA-GT 220
G+G S + G GAAG GG+ GVG++ G G AG A GGA G
Sbjct: 373 GTGGAGGSGAWLYGNGGAAGAGGNGGNNTSAGTGGVGASGGTGGNAGLIGAGGHGGAGGA 432
Query: 221 GRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGA 280
G + G V G+GG G G GG G +GG G GGA GG+ GG G
Sbjct: 433 GGNQTGGV-GNGGAGGNGGAGGAGGQLYGNGGDGG-NGGAGGANIAGGNGSDGGAAGHGG 490
Query: 281 IGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPG 340
GG +A + G+T +A A+ T G G G
Sbjct: 491 AGG----------SARLIGAGGHGGDGGAGGNTAGRRADAIAGTGGDGGNGGNGGLLS-G 539
Query: 341 NSARRADGG 349
N+ GG
Sbjct: 540 NAGAGGHGG 548
Score = 88.2 bits (217), Expect = 7e-22
Identities = 82/247 (33%), Positives = 99/247 (40%), Gaps = 31/247 (12%)
Query: 113 TGGTG-TGQSRGAG----GFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVA 167
TGGTG TG + G+G G GG AGG G + G G G G G T GN G+
Sbjct: 368 TGGTGGTGGAGGSGAWLYGNGGAAGAGGNGGNNTSAGTG------GVGASGGTGGNAGLI 421
Query: 168 GAAHGSGVSASHGSGATGAAGVADPG-GSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVG 226
GA G G+G GV + G G G G A G G G GGAG G +I G
Sbjct: 422 GAGGHGGAG---GAGGNQTGGVGNGGAGGNGGAGGAGGQLYGNGGDGGNGGAG-GANIAG 477
Query: 227 SVRGDGGVGMASGDGGLS--TGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGV 284
DGG G GG + GA G +GG G G GG+G +G GG+
Sbjct: 478 GNGSDGGAAGHGGAGGSARLIGAGGHGGDGGAGGNTAGRR-ADAIAGTGGDGGNGGNGGL 536
Query: 285 --GEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNS 342
G A A S ATT+ +G+T N GN G G+
Sbjct: 537 LSGNAGAGGHGGAGGSSTATTTTGTPPTGATGG----------NGGNGGAGGTAGFTGSG 586
Query: 343 ARRADGG 349
+GG
Sbjct: 587 GIGGNGG 593
Score = 87.4 bits (215), Expect = 1e-21
Identities = 74/200 (37%), Positives = 84/200 (42%), Gaps = 40/200 (20%)
Query: 113 TGGTGTGQSRGAGGF---------------GGVGQAGGKGWDGGPIGNGQVGEQHGAGQL 157
+G G G GAGG GG G GG G G G+G +G G G
Sbjct: 538 SGNAGAGGHGGAGGSSTATTTTGTPPTGATGGNGGNGGAGGTAGFTGSGGIG---GNGGA 594
Query: 158 GSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNG--TGAGSADAV 215
G T GN GVA + +G G G GG G G GS GNG G G+
Sbjct: 595 GGTGGNAGVALSVGSTG----------GLGGNGGSGGLGGGGGSLFGNGGAGGVGATGGN 644
Query: 216 GGAGTGRDIVGSVRGDGGVGMASG-----DGGLSTGAAGASAEGGL-----MPGFGGAPW 265
GG+G G VG G GGVG A G G S G+ GA GG G GGA
Sbjct: 645 GGSGIGPASVGGNGGKGGVGAAGGLAGQIGNGGSGGSGGAGGNGGTGDTAGNGGNGGAGA 704
Query: 266 VGGHWGLGGEGHSGAIGGVG 285
VGG+ L G G +G GG G
Sbjct: 705 VGGNAQLIGNGGNGGGGGNG 724
Score = 78.2 bits (191), Expect = 8e-19
Identities = 64/175 (36%), Positives = 78/175 (44%), Gaps = 38/175 (21%)
Query: 113 TGGTGTGQSRGAGGFGG-------VGQAGGKGWDGGPIGNGQVGEQ----HGAGQLGSTD 161
TG G G + GAGG GG VG GG G +GG G G G GAG +G+T
Sbjct: 583 TGSGGIGGNGGAGGTGGNAGVALSVGSTGGLGGNGGSGGLGGGGGSLFGNGGAGGVGATG 642
Query: 162 GNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTG 221
GN GSG+ + G G GV G+ G+ GNG GS GGAG
Sbjct: 643 GN-------GGSGIGPASVGGNGGKGGV----GAAGGLAGQIGNGGSGGS----GGAG-- 685
Query: 222 RDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEG 276
G+GG G +G+GG G AGA + G GG GG+ G G +G
Sbjct: 686 --------GNGGTGDTAGNGG--NGGAGAVGGNAQLIGNGGNGGGGGNGGTGADG 730
Score = 37.0 bits (84), Expect = 2e-06
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 7/66 (10%)
Query: 101 AQGVVSELAQDRTGGTG-------TGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHG 153
A G+ ++ +GG+G TG + G GG GG G GG G GNG G G
Sbjct: 666 AGGLAGQIGNGGSGGSGGAGGNGGTGDTAGNGGNGGAGAVGGNAQLIGNGGNGGGGGNGG 725
Query: 154 AGQLGS 159
G G+
Sbjct: 726 TGADGT 731