Pairwise Alignments
Query, 413 a.a., PE-PGRS family protein PE_PGRS39 from Mycobacterium tuberculosis H37Rv
Subject, 741 a.a., PE-PGRS family protein PE_PGRS28 from Mycobacterium tuberculosis H37Rv
Score = 187 bits (475), Expect = 9e-52
Identities = 128/313 (40%), Positives = 151/313 (48%), Gaps = 29/313 (9%)
Query: 1 MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQ 60
MS V P +AA+A ++A IGS++ AN+AAA T VLAAG D+VSA IA LFG+ A+
Sbjct: 1 MSLVIVTPETVAAAASDVARIGSSIGVANSAAAGSTTSVLAAGADEVSAAIATLFGSHAR 60
Query: 61 AYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSE------------- 107
YQAIS Q A FHDRF Q L +Y AEA NA PL + V
Sbjct: 61 EYQAISTQVAAFHDRFAQTLSAAVGSYVSAEATNAAPLATLEHNVLNALNAPTQALLGRP 120
Query: 108 -LAQDRTGGTGTGQSRGAGG-FGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPG 165
+ G GTGQ+ GAGG G G AGG G G G G G G G G G
Sbjct: 121 LIGDGAAGAPGTGQAGGAGGILWGNGGAGGSGAPGQVGGAGGAAGLFGTGGAGGA-GGAG 179
Query: 166 VAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAG----NGTGA----GSADAVGG 217
AG A GSG G GA G + GG+ G G AG GTG G VGG
Sbjct: 180 AAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVGGTGGPGGPGGPGGVGG 239
Query: 218 AGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGH 277
G + G++ G GG G A G G + G GG + G G VGGH G GG G
Sbjct: 240 TGGAGGLGGTLYGAGGHGGAGGPGPI----GGVGGHGG-VGGAAGLLGVGGHGGAGGHGA 294
Query: 278 SGAIGGVGEQVAP 290
G G GE ++P
Sbjct: 295 EGVAGAAGEDLSP 307
Score = 105 bits (263), Expect = 3e-27
Identities = 83/242 (34%), Positives = 101/242 (41%), Gaps = 29/242 (11%)
Query: 122 RGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGS 181
+GAGG GG G AGG G D G G G GAG G G+PG AG A G+G + S +
Sbjct: 394 QGAGGAGGTGGAGGVGGDRGAGGPGNQAFNAGAGGAGGHGGDPG-AGGAGGTGGAGSI-T 451
Query: 182 GATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGS--VRGDGGVGMAS- 238
GA GA G G G G N T AG+ A GG G +VG+ G+G G A
Sbjct: 452 GAQGAIGATPTSGGNGGAGGNGANATTAGTNGANGGPGGHGGLVGNGGAGGNGANGAAGT 511
Query: 239 -----------GDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQ 287
G+ G + G GA +GG + G GGA G GG G G +GG G +
Sbjct: 512 NASDSGAVGGKGNSGGNGGQGGAGGDGGTLAGNGGA------GGTGGRGADGGLGGSGAE 565
Query: 288 VAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRAD 347
A A + A G +A N H GN +PG S
Sbjct: 566 GANA-------TTAGERGQDGGKGGNGGVGGTGGNAVAPGANGGHGGNGGNPGFSGAGGL 618
Query: 348 GG 349
GG
Sbjct: 619 GG 620
Score = 94.0 bits (232), Expect = 1e-23
Identities = 96/293 (32%), Positives = 111/293 (37%), Gaps = 46/293 (15%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGK---GWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAA 170
G G G G GG GGVG A G G GG G+G G AG+ S G G G
Sbjct: 258 GAGGPGPIGGVGGHGGVGGAAGLLGVGGHGGAGGHGAEGVAGAAGEDLSPHGTSGGVGGD 317
Query: 171 HGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRG 230
G G + G GA G GG G G+ G G A V G G G + G
Sbjct: 318 AGDGGTGGRGGWLAGAGGAGGAGGVG---GTGGAGGAGFSRALIVAGDNGGDGGNGGMGG 374
Query: 231 DGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGH------SGAIGGV 284
GG G G GGL + G A G G GGA VGG G GG G+ +G GG
Sbjct: 375 AGGAGGPGGAGGLISLLGGQGAGGA--GGTGGAGGVGGDRGAGGPGNQAFNAGAGGAGGH 432
Query: 285 GEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADP----G 340
G A + + T A A G+TP T+ GN GN A+
Sbjct: 433 GGDPGAGGAGGTGGAGSITGAQGA-IGATP----------TSGGNGGAGGNGANATTAGT 481
Query: 341 NSARRADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSG 393
N A GG L G +G NG A+G NAS SG
Sbjct: 482 NGANGGPGGHG---------GLVG--------NGGAGGNGANGAAGTNASDSG 517
Score = 88.2 bits (217), Expect = 7e-22
Identities = 96/303 (31%), Positives = 121/303 (39%), Gaps = 51/303 (16%)
Query: 38 GVLAAGGDDVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALP 97
G AGG + G+ GA QA +A A GA + A
Sbjct: 395 GAGGAGGTGGAGGVGGDRGAGGPGNQAFNAGAG------------GAGGHGGDPGAGGAG 442
Query: 98 LQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQ----AGGKGWDGGPIGNGQV---GE 150
G ++ AQ G T T S G GG GG G AG G +GGP G+G + G
Sbjct: 443 GTGGAGSITG-AQGAIGATPT--SGGNGGAGGNGANATTAGTNGANGGPGGHGGLVGNGG 499
Query: 151 QHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAG 210
G G G+ N +GA G G S +G G G GG+ AG G A G G G G
Sbjct: 500 AGGNGANGAAGTNASDSGAVGGKGNSGGNG----GQGGAGGDGGTLAGNGGAGGTG-GRG 554
Query: 211 SADAVGGAGT-----------GRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPG 259
+ +GG+G G+D G G+GGVG +G ++ GA G G PG
Sbjct: 555 ADGGLGGSGAEGANATTAGERGQD--GGKGGNGGVG-GTGGNAVAPGANGGHGGNGGNPG 611
Query: 260 FGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVAT-------APAVSPATTSAVAAESGS 312
F GA GG GL G+G + A G A A AV+P T A G+
Sbjct: 612 FSGA---GGLGGLSGDGVTRAAQGATPDFADTGGKGGNGGNGANAVAPGGTGASGGAGGN 668
Query: 313 TPA 315
A
Sbjct: 669 AGA 671
Score = 87.0 bits (214), Expect = 2e-21
Identities = 89/256 (34%), Positives = 106/256 (41%), Gaps = 47/256 (18%)
Query: 101 AQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKG-WDGGPIGNGQVGEQHGAGQLGS 159
A+GV +D + G S G GG G G GG+G W G G G GAG +G
Sbjct: 294 AEGVAGAAGEDLSPH---GTSGGVGGDAGDGGTGGRGGWLAGAGGAG------GAGGVGG 344
Query: 160 TDGNPGVAGAAHGSGVSASHG-----SGATGAAGVADPGGSGAGVGSAAGNGTGAGSADA 214
T G G AG + V+ +G G GA G PGG+G G+ S G G GAG A
Sbjct: 345 T-GGAGGAGFSRALIVAGDNGGDGGNGGMGGAGGAGGPGGAG-GLISLLG-GQGAGGAGG 401
Query: 215 VGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGG 274
GGAG VG RG GG G+ + GA GA G GG P GG G GG
Sbjct: 402 TGGAGG----VGGDRGAGG----PGNQAFNAGAGGAG-------GHGGDPGAGGAGGTGG 446
Query: 275 EGH-SGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNP-GNAAH 332
G +GA G +G +P + A AT A A P G+
Sbjct: 447 AGSITGAQGAIG------------ATPTSGGNGGAGGNGANATTAGTNGANGGPGGHGGL 494
Query: 333 QGNPADPGNSARRADG 348
GN GN A A G
Sbjct: 495 VGNGGAGGNGANGAAG 510
Score = 81.3 bits (199), Expect = 9e-20
Identities = 83/278 (29%), Positives = 99/278 (35%), Gaps = 35/278 (12%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLA-AGGDDVSAGIAALFGARAQAYQAISAQAA 70
A AG GS A A A PT+G AGG+ +A A GA
Sbjct: 438 AGGAGGTGGAGSITGAQGAIGATPTSGGNGGAGGNGANATTAGTNGANG----------- 486
Query: 71 LFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGV 130
G + A G A D G G S G GG GG
Sbjct: 487 ------------GPGGHGGLVGNGGAGGNGANGAAGTNASDSGAVGGKGNSGGNGGQGGA 534
Query: 131 GQAGGK-GWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGA-AHGSGVSASHGSGATGAAG 188
G GG +GG G G G G G G+ N AG G + G G TG
Sbjct: 535 GGDGGTLAGNGGAGGTGGRGADGGLGGSGAEGANATTAGERGQDGGKGGNGGVGGTGGNA 594
Query: 189 VADPGGSGAGVGSAAGNG-TGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGA 247
VA PG +G G+ G +GAG + G G R G+ G G+GG
Sbjct: 595 VA-PGANGGHGGNGGNPGFSGAGGLGGLSGDGVTRAAQGATPDFADTGGKGGNGG---NG 650
Query: 248 AGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVG 285
A A A GG G + GG+ G GG+G IG G
Sbjct: 651 ANAVAPGGT----GASGGAGGNAGAGGKGGENIIGDGG 684
Score = 47.8 bits (112), Expect = 1e-09
Identities = 40/106 (37%), Positives = 45/106 (42%), Gaps = 30/106 (28%)
Query: 117 GTGQSRGAGGFGGVGQAGGKG--WDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSG 174
GTG S GAGG G G GG+ DGG GNG G + GAG L G
Sbjct: 658 GTGASGGAGGNAGAGGKGGENIIGDGGG-GNGGAGGKGGAGTL---------------LG 701
Query: 175 VSASHGSGATGAAG-VADPGGSGAGVGSAAGNGTGAGSADAVGGAG 219
++ +G G G DP GSG GAG A GGAG
Sbjct: 702 LTVFGDNGGAGVLGDSTDPDGSG-----------GAGGAGGAGGAG 736
Score = 32.3 bits (72), Expect = 5e-05
Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 12/62 (19%)
Query: 114 GGTGTGQSRGAGG---------FGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNP 164
GG G G + G GG FG G AG G P G+G G GAG G G+P
Sbjct: 683 GGGGNGGAGGKGGAGTLLGLTVFGDNGGAGVLGDSTDPDGSGGAG---GAGGAGGAGGDP 739
Query: 165 GV 166
+
Sbjct: 740 TI 741