Pairwise Alignments
Query, 413 a.a., PE-PGRS family protein PE_PGRS39 from Mycobacterium tuberculosis H37Rv
Subject, 767 a.a., PE-PGRS family protein PE_PGRS21 from Mycobacterium tuberculosis H37Rv
Score = 202 bits (515), Expect = 2e-56
Identities = 145/320 (45%), Positives = 162/320 (50%), Gaps = 40/320 (12%)
Query: 1 MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQ 60
MS V AP VLAA+A +LA IGST+ ANAAA APT VLAAG D+VSA IA+LFGA Q
Sbjct: 1 MSFVVVAPEVLAAAASDLAGIGSTLAQANAAALAPTTAVLAAGADEVSAAIASLFGAHGQ 60
Query: 61 AYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSEL------------ 108
AYQA+SAQ + FH +F+Q L AYA AEA N + AQ V +L
Sbjct: 61 AYQAVSAQMSAFHAQFMQALTGAGGAYAAAEAVN---VSAAQSVEQDLLAAINARFERIF 117
Query: 109 -----AQDRTGGTGT-----GQSRGAGGFGG----VGQAGGKGWDGGPIGNGQVGEQHGA 154
GG G G G GG GG VG AGG G G IGNG G G
Sbjct: 118 GRPLIGDGANGGPGQDGGPGGLLYGNGGNGGTSTTVGMAGGNGGAAGLIGNGGFGGGGGP 177
Query: 155 GQLGSTDG------NPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGA--GVGSAAGNG 206
G G G G AG A G GV+ GA GA G GG G G A G G
Sbjct: 178 GAAGGNGGAGGWLFGNGGAGGAGGLGVAPGVPGGAGGAGGAGGVGGPAGLWGHGGAGGAG 237
Query: 207 TGAGSADAVGGAGT-GRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPW 265
GAG A A G GT G G V G GGVG A G GG G AGA +GG + G GG
Sbjct: 238 -GAGVAGAGGFEGTIGAGGAGGVGGAGGVGGAGGAGGWLYGDAGAGGDGG-VGGAGGTGG 295
Query: 266 VGGHWGLGGEGHSGAIGGVG 285
+G G GG G +G +GG G
Sbjct: 296 LGNRGGAGGAGGAGGVGGAG 315
Score = 106 bits (264), Expect = 3e-27
Identities = 99/305 (32%), Positives = 113/305 (37%), Gaps = 59/305 (19%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL 71
A AG + GS GV AGG G+ L GA A +
Sbjct: 396 AGGAGVFSLFGSGGGPGGNGGVGGVGGVGGAGGRAGLFGVGGLGGAGGDAGDS------- 448
Query: 72 FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGT--GTGQSRGAGGFGG 129
G + A L G V + D G G G + GAGG GG
Sbjct: 449 -----------GEGGFGGPGLAGGLFGNPGNGGVGGIGGDAAAGGAGGAGGNGGAGGNGG 497
Query: 130 V----GQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATG 185
G AGG G DGG G G GAG LGS G AG V GA G
Sbjct: 498 WLFGNGGAGGSGGDGGAAGRG------GAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGG 551
Query: 186 AAGVADPGGSGAGVGSAAGNGTG--------AGSADAVGGAG--------TGRDIVGSVR 229
AG+ GG+G G+ A G G AGS A+GGAG G G V
Sbjct: 552 TAGLFGDGGAGGAGGAGAAGGFGGISAATPSAGSEGAMGGAGGVGGNARLLGTGGAGGVG 611
Query: 230 GDGGVGMASGDGGLST-----------GAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHS 278
G GG G G GG++T GA GA GG G GG W+ G G GG G +
Sbjct: 612 GGGGAGGDGGRGGVATPGGQGGDAGDGGAGGAGGNGGGASGAGG--WLLGTGGAGGAGGN 669
Query: 279 GAIGG 283
G GG
Sbjct: 670 GGNGG 674
Score = 103 bits (258), Expect = 1e-26
Identities = 93/261 (35%), Positives = 107/261 (40%), Gaps = 39/261 (14%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGW------DGGPIGNGQVGEQHGAGQLGSTDGNPGVA 167
GG G S G GG GG G AGG G GGP GNG VG G G G G GV
Sbjct: 377 GGGGAAGSGGDGGTGGQGGAGGAGVFSLFGSGGGPGGNGGVGGVGGVGGAGGRAGLFGVG 436
Query: 168 GAAHGSGVSASHGSGATGAAGVA-----DPGGSG-AGVGSAAGNGTGAGSADAVGGAGTG 221
G G + G G G G+A +PG G G+G A G GAG A GGAG
Sbjct: 437 GLGGAGGDAGDSGEGGFGGPGLAGGLFGNPGNGGVGGIGGDAAAG-GAGGAGGNGGAGGN 495
Query: 222 RDIVGSVRGDGGVGMASGDGGLS--TGAAGASAEGGL----------MPGFGGAPWVGGH 269
G + G+GG G + GDGG + GA + GG+ G GGA GG
Sbjct: 496 G---GWLFGNGGAGGSGGDGGAAGRGGAGNLGSAGGINAPAGNPGSGSVGIGGAGGAGGT 552
Query: 270 WGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGN 329
GL G+G +G GG G A +S AT SA +E A G
Sbjct: 553 AGLFGDGGAGGAGGAG-----AAGGFGGISAATPSA-GSEGAMGGAGGVGGNARLLGTGG 606
Query: 330 AAHQGNPADPGNSARRADGGR 350
A G G DGGR
Sbjct: 607 AGGVG-----GGGGAGGDGGR 622
Score = 101 bits (252), Expect = 7e-26
Identities = 73/184 (39%), Positives = 84/184 (45%), Gaps = 20/184 (10%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKG-W---DGGPIGNGQVGEQHGAGQLGSTDGNPGVAGA 169
G G G + G GG GGVG AGG G W D G G+G VG G G LG+ G G GA
Sbjct: 249 GTIGAGGAGGVGGAGGVGGAGGAGGWLYGDAGAGGDGGVGGAGGTGGLGNRGGAGGAGGA 308
Query: 170 AHGSGVSASHGSGATGAAGVADPGGSGAGVG--------SAAGNGTGAGSADAVGGAGTG 221
G + G G AG G GAG+G S +G G G A GGAG
Sbjct: 309 GGVGGAGGAAGLWGGGGAGGVGGTGGGAGLGAQSVTFSSSLSGLSGGDGGAGGAGGAGGA 368
Query: 222 RDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAI 281
G + G GG + GDGG TG G + G+ FG GG G GG G G +
Sbjct: 369 GGTGGWLYGGGGAAGSGGDGG--TGGQGGAGGAGVFSLFGS----GG--GPGGNGGVGGV 420
Query: 282 GGVG 285
GGVG
Sbjct: 421 GGVG 424
Score = 97.1 bits (240), Expect = 2e-24
Identities = 89/286 (31%), Positives = 110/286 (38%), Gaps = 52/286 (18%)
Query: 115 GTGTGQSRGAGGFGGVGQAGGK---------GWDGGPIGNGQVGEQHGAGQLGSTDGNPG 165
G G G + G GG GGVG AGG+ G GG G+ G G G G GNPG
Sbjct: 408 GGGPGGNGGVGGVGGVGGAGGRAGLFGVGGLGGAGGDAGDSGEGGFGGPGLAGGLFGNPG 467
Query: 166 VAG--------AAHGSGVSASHG---------------SGATGAAGVADPGGSG-----A 197
G AA G+G + +G G+ G G A GG+G
Sbjct: 468 NGGVGGIGGDAAAGGAGGAGGNGGAGGNGGWLFGNGGAGGSGGDGGAAGRGGAGNLGSAG 527
Query: 198 GVGSAAGN-GTGAGSADAVGGAGTGRDIV--GSVRGDGGVGMASGDGGLSTGAAGASAEG 254
G+ + AGN G+G+ GGAG + G G GG G A G GG+S A +EG
Sbjct: 528 GINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAGGAGGAGAAGGFGGISAATPSAGSEG 587
Query: 255 GL-----------MPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATT 303
+ + G GGA VGG G GG+G G + G Q A A
Sbjct: 588 AMGGAGGVGGNARLLGTGGAGGVGGGGGAGGDGGRGGVATPGGQGGDA-GDGGAGGAGGN 646
Query: 304 SAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
A+ +G A A N GN G P N GG
Sbjct: 647 GGGASGAGGWLLGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGG 692
Score = 95.1 bits (235), Expect = 6e-24
Identities = 84/251 (33%), Positives = 100/251 (39%), Gaps = 25/251 (9%)
Query: 114 GGTGTGQSRGAGGFGGVGQ----AGGKGWDGGPIGNGQVGEQHGAG--QLGSTDGNPGVA 167
G G G + GAGG GG G GG GG G G G GAG L + G PG
Sbjct: 355 GDGGAGGAGGAGGAGGTGGWLYGGGGAAGSGGDGGTGGQGGAGGAGVFSLFGSGGGPGGN 414
Query: 168 GAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGS 227
G G G GA G AG+ GG G G A +G G + G G G
Sbjct: 415 GGVGGVG----GVGGAGGRAGLFGVGGLGGAGGDAGDSGEGGFGGPGLAGGLFGNPGNGG 470
Query: 228 VRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQ 287
V G GG A G GG + G GA GG + G GGA GG G G G +G +G G
Sbjct: 471 VGGIGGDAAAGGAGG-AGGNGGAGGNGGWLFGNGGAGGSGGDGGAAGRGGAGNLGSAGGI 529
Query: 288 VAPA-------VATAPAVSPATTSAVAAESGSTPATKAQA-------MHATTNPGNAAHQ 333
APA V A T+ + + G+ A A A AT + G+
Sbjct: 530 NAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAGGAGGAGAAGGFGGISAATPSAGSEGAM 589
Query: 334 GNPADPGNSAR 344
G G +AR
Sbjct: 590 GGAGGVGGNAR 600
Score = 90.1 bits (222), Expect = 2e-22
Identities = 93/283 (32%), Positives = 110/283 (38%), Gaps = 52/283 (18%)
Query: 12 AASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL 71
AA G +GS NA A P +G + GG + G A LFG A A A
Sbjct: 514 AAGRGGAGNLGSA-GGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGG----AGGAGGA- 567
Query: 72 FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVG 131
AA + A P ++G + G G G + G GG G
Sbjct: 568 ------------GAAGGFGGISAATPSAGSEGAMG-------GAGGVGGNARLLGTGGAG 608
Query: 132 QAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVAD 191
GG G GG G G V G G D G AG A G +G GA+GA G
Sbjct: 609 GVGGGGGAGGDGGRGGVATPGGQG----GDAGDGGAGGAGG------NGGGASGAGGWLL 658
Query: 192 PGGSGAGVGSAAGNGTGAGSAD-----AVGGAGTGRDIVGSVRGDGGVG-MASGDGGLST 245
G G G GNG AG + + GAG G G V G+G G GDGG +
Sbjct: 659 GTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGG----GGVGGNGATGPWLFGDGGPTP 714
Query: 246 GAAGASAEGGLMPGFGGAPWV---GGHWGLGGEGHSGAIGGVG 285
G+ GA A G G GG + GGH G GG G GG G
Sbjct: 715 GSTGAGAAG----GHGGDAQLIGNGGHGGAGGTGVPNGSGGAG 753
Score = 87.8 bits (216), Expect = 1e-21
Identities = 73/210 (34%), Positives = 89/210 (42%), Gaps = 29/210 (13%)
Query: 114 GGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGS 173
GG G G+G AGG G G G+G G GAG G+ G G++ A +
Sbjct: 527 GGINAPAGNPGSGSVGIGGAGGAGGTAGLFGDGGAG---GAGGAGAAGGFGGISAATPSA 583
Query: 174 GVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGG 233
G + G GA G G A G+G G G G GAG GG T G GDGG
Sbjct: 584 GSEGAMG-GAGGVGGNARLLGTGGAGG--VGGGGGAGGDGGRGGVATPGG-QGGDAGDGG 639
Query: 234 VGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGG---------------HWGLGGEGHS 278
G A G+GG GAS GG + G GGA GG ++GL G G
Sbjct: 640 AGGAGGNGG------GASGAGGWLLGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGG 693
Query: 279 GAIGGVGEQVAPAVATAPAVSPATTSAVAA 308
G +GG G P + +P +T A AA
Sbjct: 694 GGVGGNG-ATGPWLFGDGGPTPGSTGAGAA 722
Score = 38.9 bits (89), Expect = 5e-07
Identities = 44/172 (25%), Positives = 54/172 (31%), Gaps = 15/172 (8%)
Query: 16 GELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAAL---- 71
G +G R A G AGGD G+A G A + A
Sbjct: 590 GGAGGVGGNARLLGTGGAGGVGGGGGAGGDGGRGGVATPGGQGGDAGDGGAGGAGGNGGG 649
Query: 72 FHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAG------ 125
+L G A A N + G + GG G G + G
Sbjct: 650 ASGAGGWLLGTGGAGGAGGNGGNGGKAGFSPGPTNFGLNGAGGGGGVGGNGATGPWLFGD 709
Query: 126 -----GFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHG 172
G G G AGG G D IGNG G G G + G G++G G
Sbjct: 710 GGPTPGSTGAGAAGGHGGDAQLIGNGGHGGAGGTGVPNGSGGAGGLSGLLFG 761