Pairwise Alignments
Query, 413 a.a., PE-PGRS family protein PE_PGRS39 from Mycobacterium tuberculosis H37Rv
Subject, 882 a.a., PE-PGRS family protein PE_PGRS14 from Mycobacterium tuberculosis H37Rv
Score = 205 bits (522), Expect = 4e-57
Identities = 153/380 (40%), Positives = 186/380 (48%), Gaps = 37/380 (9%)
Query: 1 MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQ 60
MS V AAP+++A + +LA IG+++ AANAAAA PT+G+LAA GD+VSA IAALF + Q
Sbjct: 1 MSFVIAAPDLVAMATEDLAGIGASLTAANAAAAVPTSGLLAAAGDEVSAAIAALFSSHGQ 60
Query: 61 AYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQ----GVVSELAQDRTGGT 116
YQA+SAQAA FH RFVQ L AYA AEAANA PLQ + G ++ A +G
Sbjct: 61 QYQAMSAQAAAFHARFVQALAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRP 120
Query: 117 GTGQSRGAGGFGGVGQAGGK-GW---DGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHG 172
G G G G G+AGG GW +GG G+G G+ GAG G+ G GA
Sbjct: 121 FIG--NGTNGAPGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAGLLGHGGTGGA--- 175
Query: 173 SGVSASHGSGAT-----GAAGVADPGGSGAGVGSAAGNGT--GAGSADAVGGA--GTGRD 223
G AS G G T G+ G GGSG G G A GN G G GGA G G
Sbjct: 176 GGTGASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMFGIGGNGGAGGAASGVGNG 235
Query: 224 IVGSVRGDGG----VGMASGDGG-LSTGAAGASAEG----GLMPGFGGAPWVGGHWGLGG 274
VG G GG +G A G GG +TG GA G GL G GG+ GG +G
Sbjct: 236 GVGGAGGAGGALVAIGGAGGAGGAATTGTGGAGGAGSNALGLFLGLGGSGGQGGDSAMGS 295
Query: 275 EGHSGAIGGVGEQVAP-----AVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGN 329
G GA GG G +P + A A T+ A +G + + G
Sbjct: 296 GGAGGA-GGSGGAASPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALDLSWGG 354
Query: 330 AAHQGNPADPGNSARRADGG 349
A G A G GG
Sbjct: 355 AGGNGGAATTGTGGAGGTGG 374
Score = 98.6 bits (244), Expect = 7e-25
Identities = 104/354 (29%), Positives = 125/354 (35%), Gaps = 61/354 (17%)
Query: 21 IGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAALFHDRFVQIL 80
IG A AA+ GV AGG + A+ GA A +
Sbjct: 219 IGGNGGAGGAASGVGNGGVGGAGG--AGGALVAIGGAGGAGGAATTGTGG---------- 266
Query: 81 QEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGK---- 136
A +NAL L G +GG G + G+GG GG G +GG
Sbjct: 267 -------AGGAGSNALGLFLGLG--------GSGGQGGDSAMGSGGAGGAGGSGGAASPF 311
Query: 137 GWD---GGPIGNGQVGEQHGAGQLGSTDGNPGVA-------GAAHGSGVSASHGSGATGA 186
G D GG G+G G GAG G G+ G G A G+G +A+ G+G G
Sbjct: 312 GIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALDLSWGGAGGNGGAATTGTGGAGG 371
Query: 187 AG----VADPGGSGAGVGSAAGNG---TGAGSADAVGGAGTGRDIVGSVRGDGGVGMASG 239
G D G GA G A G G TGAG GG G G G GVG A G
Sbjct: 372 TGGFAVAPDFIGFGAAYGGAGGLGGAATGAGGTGGTGGVGAG----GFAALGVGVGGAGG 427
Query: 240 DGGLSTGAAGASAEG----GLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATA 295
GG +T G G GL+ G GGA GG G GH G G + +
Sbjct: 428 AGGAATETGGIGGAGGLGVGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGV 487
Query: 296 PAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGG 349
V A T ++G G A G A G GG
Sbjct: 488 GGVGGAAT-----DTGGNGGAGGSGTGLLGGVGGAGGHGGGASVGTGGSGGAGG 536
Score = 93.6 bits (231), Expect = 2e-23
Identities = 99/305 (32%), Positives = 117/305 (38%), Gaps = 40/305 (13%)
Query: 15 AGELAAIGSTMRAANAA--AAAPTAGVLAAGGDDVS--AGIAALFGARAQAYQAISAQAA 70
AG AA+G + A A AA T G+ AGG V G G A
Sbjct: 412 AGGFAALGVGVGGAGGAGGAATETGGIGGAGGLGVGLLGGAGGAGGPGGAASAGSGGHGG 471
Query: 71 LFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAG---GF 127
D I GA + A G GG G G G G
Sbjct: 472 TGGDALGLI---GAGIGGVGGVGGAATDTGGNGGAGGSGTGLLGGVGGAGGHGGGASVGT 528
Query: 128 GGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAA 187
GG G AGG G+ G +G G G G G +G N G G+A G+ ++A G+GA G
Sbjct: 529 GGSGGAGGDGF--GFVGAGGNGGNAGTG-VGVNGANGGNGGSATGA-LAAVGGAGAAGGD 584
Query: 188 GVADPGGSGAGVGSAAGNGTGAGSADAVGG-AGTGRDIVGSVRGDGGVGMASGDGGLSTG 246
+ GG G GSA G G A A GG A TG VG G GG G AS G++
Sbjct: 585 ATSGTGGFGGAGGSARGLIFALGGAGAAGGDASTG---VGGPGGPGGTGTASSPFGIAIA 641
Query: 247 AAGASAEGG---------------------LMPGFGGAPWVGG-HWGLGGEGHSGAIGGV 284
GA A+GG L GFGGA GG G G G +G GG
Sbjct: 642 IGGAGAQGGAGTSGATGGAGGDGVFEGIAVLGLGFGGAAGAGGAATGDGATGGAGGFGGA 701
Query: 285 GEQVA 289
G +A
Sbjct: 702 GAGIA 706
Score = 92.0 bits (227), Expect = 6e-23
Identities = 97/291 (33%), Positives = 117/291 (40%), Gaps = 42/291 (14%)
Query: 116 TGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGV 175
TGTG + G GGF G G G G G G GAG G T G AA G GV
Sbjct: 364 TGTGGAGGTGGFAVAPDFIGFGAAYGGAG-GLGGAATGAGGTGGTGGVGAGGFAALGVGV 422
Query: 176 SASHGSG--ATGAAGVADPGGSGAGVGSAAGNG-----TGAGSADAVGGAGTGRDIVG-- 226
+ G+G AT G+ G G GVG G G GA SA + G GTG D +G
Sbjct: 423 GGAGGAGGAATETGGIG--GAGGLGVGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLI 480
Query: 227 --SVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGV 284
+ G GGVG A+ D G + GA G+ GL+ G GGA GGH G G G+ G
Sbjct: 481 GAGIGGVGGVGGAATDTGGNGGAGGSGT--GLLGGVGGA---GGHGGGASVGTGGSGGAG 535
Query: 285 GEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSAR 344
G+ A + T V +G + A+ A G A G A G
Sbjct: 536 GDGFGFVGAGGNGGNAGTGVGVNGANGGNGGSATGALAAV---GGAGAAGGDATSGTGGF 592
Query: 345 RADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSGRP 395
GG S RGL + A G A GD ++G G P
Sbjct: 593 GGAGG-----------SARGL---------IFALGGAGAAGGDASTGVGGP 623
Score = 80.9 bits (198), Expect = 1e-19
Identities = 99/311 (31%), Positives = 119/311 (38%), Gaps = 48/311 (15%)
Query: 13 ASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISA----- 67
++ G LAA+G AA A + T G AGG I AL GA A A +
Sbjct: 567 SATGALAAVGGA-GAAGGDATSGTGGFGGAGGS-ARGLIFALGGAGAAGGDASTGVGGPG 624
Query: 68 ----QAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTG--------- 114
+ I GA A A + A GV +A G
Sbjct: 625 GPGGTGTASSPFGIAIAIGGAGAQGGAGTSGATGGAGGDGVFEGIAVLGLGFGGAAGAGG 684
Query: 115 -GTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGS 173
TG G + GAGGFGG G AG + G + +G G GAG G+ G G GA G
Sbjct: 685 AATGDGATGGAGGFGGAG-AGIANFLGFSVLHGGAG---GAG--GTATGTGGNGGAGGGG 738
Query: 174 GVSASHGSGATGAAGVADPGGSGAGV-GSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDG 232
G+S+ G G G GG GV G G+G G A AVG A G G G
Sbjct: 739 GLSSPVILGI-GIGGAGGDGGGALGVLGGMGGDGGDGGEAVAVGIAVGGAGGAGGAAPTG 797
Query: 233 GVGMASGDGGLSTGAAGASAEGG-LMPGFGG-----------------APWVGGHWGLGG 274
G A G+GG + G G GG GFG AP G+ G GG
Sbjct: 798 N-GGAGGNGGDALGLVGVGGNGGNAGTGFGANTGGNGGDTTIVVNGMLAPSTLGYGGNGG 856
Query: 275 EGHSGAIGGVG 285
G +G GG G
Sbjct: 857 NGVNGGAGGTG 867
Score = 28.5 bits (62), Expect = 8e-04
Identities = 23/74 (31%), Positives = 24/74 (32%), Gaps = 16/74 (21%)
Query: 111 DRTGGTGTGQSRGAGGFGGVGQAGGKGWD----------------GGPIGNGQVGEQHGA 154
D G G G + G G G GG G D GG GNG G G
Sbjct: 807 DALGLVGVGGNGGNAGTGFGANTGGNGGDTTIVVNGMLAPSTLGYGGNGGNGVNGGAGGT 866
Query: 155 GQLGSTDGNPGVAG 168
G G PG G
Sbjct: 867 GGKAGVFGAPGQNG 880