Pairwise Alignments

Query, 904 a.a., Probable DNA polymerase I PolA from Mycobacterium tuberculosis H37Rv

Subject, 944 a.a., DNA polymerase I from Dickeya dianthicola ME23

 Score =  498 bits (1282), Expect = e-145
 Identities = 336/950 (35%), Positives = 499/950 (52%), Gaps = 79/950 (8%)

Query: 17  LMLLDGNSLAFRAFYALPAENFKTRGGLTTNAVYGFTAMLINLLRDEAPTHIAAAFDVSR 76
           L+L+DG+S  +RA++A P        G  T A+YG   ML +LL+   P+H+A  FD   
Sbjct: 9   LILVDGSSYLYRAYHAFPP--LTNSAGEPTGAMYGVLNMLRSLLQQYHPSHVAVVFDAKG 66

Query: 77  QTFRLQRYPEYKANRSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIATLATQAE 136
           +TFR   +  YK++R   PD+   QI+    ++ A+G+ +LS  G EADD+I TLA QAE
Sbjct: 67  KTFRDDLFEHYKSHRPPMPDDLRAQIEPLHRMVKAMGLPLLSVSGVEADDVIGTLAQQAE 126

Query: 137 NEGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQYPDFAAL 196
             G  VL+ TGD+D  QLV+ ++T++         T   P+ V  KYG+ P    DF AL
Sbjct: 127 RAGKPVLISTGDKDMAQLVTPNITLINTMNN----TILGPDEVCAKYGIPPSLIIDFLAL 182

Query: 197 RGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVRGKVGDALRANLASVVRNRE- 255
            GD SDN+PG+PGVGEKTA   +A  G L +L  ++D + G      +   A + +N+E 
Sbjct: 183 MGDSSDNIPGVPGVGEKTAQALLAGLGGLDALYADLDKIAGLTFRGAKTMAAKLEQNKEV 242

Query: 256 ------LTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLEF-RVLRD------------ 296
                 L  +  DV L    + L +   D   +  LF   EF R L D            
Sbjct: 243 AYLSYQLATIKTDVELELGCEQLTVNEPDAVELRELFTRYEFKRWLADVEAGQWLQGGKK 302

Query: 297 ----RLFDTLAAAGGPEVDEGFDVRGG---ALAPGTVRQWL------AEHAGDGRRAGLT 343
                 F    A G P+       + G    L    +  WL      A  + D    GL 
Sbjct: 303 NPPATPFVKATAGGEPKEAASVLSQDGYVTILDEKVLLDWLERIKTAALFSFDTETDGLD 362

Query: 344 VVGTHLPHGGDATAMAVAAADGEGAYLD--------------TATLTPDDD--------- 380
            +  +L        +++A   GE AYL               ++T++P            
Sbjct: 363 TLTANL------VGVSLAIKPGEAAYLPLGHITSRVYSSNIYSSTVSPATRMSTQLGSDR 416

Query: 381 --AALAAWLADPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDD 438
             A L   L D    K     K     +A  G  L G+  DT L +Y++        +D 
Sbjct: 417 VLALLKPLLEDEGIRKIGQNLKFDKGVMARCGIDLRGIAFDTMLESYVLDSVAGRHDMDS 476

Query: 439 LSLRYLRRELRA--ETPQQQQLSLLDDDDTDAETIQTTILRARAVIDLADALDAELA-RI 495
           LS RYL+ +     E   + +  L  D    A+        A   + L + L A+L  + 
Sbjct: 477 LSERYLQHKTITFEEIAGKGKKQLTFDRIPLAQASVYAAEDADVTLRLHETLWAKLEPQQ 536

Query: 496 DSTALLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQIRDAAEAAYGVIGKQINL 555
           +   +   +++P+  VL+++E  G+ ++  +L E   +   ++ +    A+ + G+  NL
Sbjct: 537 ELRKVFQNIDMPLVPVLSRIERTGVLINTAILAEHSRELTQRLAELEVQAHELAGEAFNL 596

Query: 556 GSPKQLQVVLFDELGMPKTKRTKTGY-TTDADALQSLFDKTGHPFLQHLLAHRDVTRLKV 614
            SPKQL  +L+++L +P  K+T  G  +T+ + L  L     +P  + +L HR + +LK 
Sbjct: 597 SSPKQLGAILYEKLQLPVIKKTPKGAPSTNEEVLVEL--ALDYPLPKLILEHRGLAKLKS 654

Query: 615 T-VDGLLQAV-AADGRIHTTFNQTIAATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVGDG 672
           T  D L Q +     R+HT+++Q + ATGRLSS++PNLQNIP+R + GRRIR AF+  +G
Sbjct: 655 TYTDKLPQMINPLTKRVHTSYHQAVTATGRLSSSDPNLQNIPVRNEEGRRIRQAFIAPEG 714

Query: 673 YAELMTADYSQIEMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRV 732
           Y  ++ ADYSQIE+RIMAHLS D GL+ AF+ G D+H   A+  FG+P+D VT E RR  
Sbjct: 715 Y-RILAADYSQIELRIMAHLSRDAGLLRAFSHGLDIHRATAAEVFGLPLDRVTTEQRRSA 773

Query: 733 KAMSYGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERARKDGYTST 792
           KA+++GL YG+SA+GLS+QL I   EA + M+ YF R+ GV++Y+    ++A   GY ST
Sbjct: 774 KAINFGLIYGMSAFGLSRQLAIPRNEAQKYMNLYFERYPGVQEYMERTRQQAAAQGYVST 833

Query: 793 VLGRRRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVAMIQVDKALNEAQLASRML 852
           + GRR YLP++ S N   R+AAERAA+NAP+QG+AADIIK AMI +D  L + +    ML
Sbjct: 834 LDGRRLYLPDIHSRNANSRKAAERAAINAPMQGTAADIIKKAMIAIDAWLQQEKPLVTML 893

Query: 853 LQVHDELLFEIAPGERERVEALVRDKMGGAYPLDVPLEVSVGYGRSWDAA 902
           +QVHDEL+FE+     +     +R+ M G   LDVPL+V +G G +WD A
Sbjct: 894 MQVHDELVFEVHHSVLDETSEKIRNLMEGCMQLDVPLQVDIGTGSNWDQA 943