Pairwise Alignments
Query, 904 a.a., Probable DNA polymerase I PolA from Mycobacterium tuberculosis H37Rv
Subject, 998 a.a., DNA polymerase I from Agrobacterium fabrum C58
Score = 336 bits (861), Expect = 5e-96
Identities = 212/590 (35%), Positives = 320/590 (54%), Gaps = 31/590 (5%)
Query: 330 LAEHAGDGRRAGLTVVGTHLPH----GGDATAMAVAAADGEGAYLDTATLTPDDDAALAA 385
+A++ D + L H GGD + + A+G+ + + D
Sbjct: 422 IADNGKDASGTDIRAAYVPLTHKTGSGGDLFSDGIKLAEGQAPFAEALERLKD------- 474
Query: 386 WLADPAKPKALHEAKAAVHDLAGRGWTLEGVTSDTALAAYLVRPGQRSFTLDDLSLRYLR 445
L D A K K + G + DT L +Y++ G+ + +D LS R+L
Sbjct: 475 LLEDEAVLKVAQNLKYDYLLMKRHGVVMRSF-DDTMLISYVLEAGKTTHGMDTLSERWLG 533
Query: 446 ------RELRAETPQQQQLSLLDDDDTDAETIQTTILRARAVIDLADALDAELARIDSTA 499
+++ ++ D A + A + L AL L T
Sbjct: 534 HTPIAYKDVTGSGKSSITFDFVNIDKATAYAAED----ADVTLRLWMALKPRLVSERLTK 589
Query: 500 LLGEMELPVQRVLAKMESAGIAVDLPMLTELQSQFGDQIRDAAEAAYGVIGKQINLGSPK 559
+ +E P+ VLA ME GI VD +L+ L + + E Y + G++ N+GSPK
Sbjct: 590 VYERLERPLVPVLAHMEERGITVDRQILSRLSGELAQKAASFEEEIYELAGERFNIGSPK 649
Query: 560 QLQVVLFDELGMPKTKRTKTG-YTTDADALQSLFDKTGHPFLQHLLAHRDVTRLKVTVDG 618
QL +LF +G+P +TKTG ++T A L+ L + G + ++ R +T+LK T
Sbjct: 650 QLGDILFGRMGLPGGSKTKTGQWSTSAQVLEDLAAE-GAELPRKIVDWRQLTKLKSTYTD 708
Query: 619 LLQAVA--ADGRIHTTFNQTIAATGRLSSTEPNLQNIPIRTDAGRRIRDAFVVGDGYAEL 676
L + R+HT++ TGRLSS+EPNLQNIP+RT GR+IR AF+ G+ +L
Sbjct: 709 ALPSYIHPETKRVHTSYALASTTTGRLSSSEPNLQNIPVRTAEGRKIRTAFISTPGH-KL 767
Query: 677 MTADYSQIEMRIMAHLSGDEGLIEAFNTGEDLHSFVASRAFGVPIDEVTGELRRRVKAMS 736
++ADYSQIE+R++AH++ L AF G D+H+ AS FGVP++ + E+RRR KA++
Sbjct: 768 LSADYSQIELRVLAHVADIPQLRNAFENGIDIHAMTASEMFGVPVEGMPSEVRRRAKAIN 827
Query: 737 YGLAYGLSAYGLSQQLKISTEEANEQMDAYFARFGGVRDYLRAVVERARKDGYTSTVLGR 796
+G+ YG+SA+GL+ QL I+ EA + + YF RF G+RDY+ A AR++GY T+ GR
Sbjct: 828 FGIIYGISAFGLANQLSIARSEAGDYIKKYFERFPGIRDYMEATKAFARENGYVETIFGR 887
Query: 797 RRYLPELDSSNRQVREAAERAALNAPIQGSAADIIKVAMIQVDKALNEAQLASRMLLQVH 856
R + PE+ SSN V+ ERAA+NAPIQGSAADII+ AMI+++ AL +L++RMLLQVH
Sbjct: 888 RAHYPEIRSSNPSVKAFNERAAINAPIQGSAADIIRRAMIRIEPALEAEKLSARMLLQVH 947
Query: 857 DELLFEIAPGERER----VEALVRDKMGGAYPLDVPLEVSVGYGRSWDAA 902
DEL+FE+ E E+ V +++ D A + VPL+V +WD A
Sbjct: 948 DELIFEVEEAEIEKTLPVVVSVMEDAAMPAISMRVPLKVDARAADNWDEA 997
Score = 189 bits (481), Expect = 6e-52
Identities = 140/395 (35%), Positives = 196/395 (49%), Gaps = 32/395 (8%)
Query: 17 LMLLDGNSLAFRAFYALPAENFKTRGGLTTNAVYGFTAMLINLLRDE-------APTHIA 69
L L+DG+ FRAF+A+P N K+ GL NAV GF ML LL+D PTH A
Sbjct: 7 LFLVDGSGFIFRAFHAIPPLNRKS-DGLPVNAVSGFCNMLWKLLKDARNTDVGVTPTHFA 65
Query: 70 AAFDVSRQTFRLQRYPEYKANRSSTPDEFAGQIDITKEVLGALGITVLSEPGFEADDLIA 129
FD S +TFR + Y YKANRS+ P++ Q + +E A + + GFEADD+IA
Sbjct: 66 VIFDYSSKTFRNELYDLYKANRSAPPEDLVPQFGLIREATRAFNLPCIETEGFEADDIIA 125
Query: 130 TLATQAENEGYRVLVVTGDRDALQLVSDDVTVLYPRKGVSELTRFTPEAVVEKYGLTPRQ 189
T A QAE G V +++ D+D +QLV+ +V + K + V+EK+G+ P +
Sbjct: 126 TYARQAEAIGADVTIISSDKDLMQLVTANVHMYDAMKD----KQIGVPDVIEKWGVGPEK 181
Query: 190 YPDFAALRGDPSDNLPGIPGVGEKTAAKWIAEYGSLRSLVDNVDAVR-GKVGDALRANLA 248
D A+ GD +DN+PGIPG+G KTAA+ + EYG L +L+ ++ K + + AN
Sbjct: 182 MIDLQAMTGDSTDNVPGIPGIGPKTAAQLLEEYGDLDTLLARAGEIKQQKRRENIIANAE 241
Query: 249 SVVRNRELTDLVRDVPLAQTPDTLRLQPWDRDHIHRLFDDLEFRVLRDRLFDTLAAAGGP 308
+R+L L DVPL Q+ + L L+P + + +EF L R
Sbjct: 242 LARLSRQLVALRTDVPLEQSLEELVLEPQNGPKLIAFLKAMEFTTLTRR----------- 290
Query: 309 EVDEGFDVRGGALAPGTVR-QWLAE-HAGDGRRAGLTVVGTHLPHGGDATAMAVAAAD-- 364
V E D A+ P V QW A+ H D + G G + A AVA A
Sbjct: 291 -VAEATDSDASAIDPANVPVQWGADAHGPDLDAPAAAMAGDVSAEGNNRPASAVAPAKRM 349
Query: 365 -GEGAYLDTATLTPDDDAALAAWLADPAKPKALHE 398
GEG+ A LT A AA D A+ +
Sbjct: 350 IGEGS--TPADLTTARQALFAATKIDTTAYTAIRD 382