Pairwise Alignments
Query, 923 a.a., PE-PGRS family protein PE_PGRS16 from Mycobacterium tuberculosis H37Rv
Subject, 853 a.a., PE-PGRS family protein PE_PGRS22 from Mycobacterium tuberculosis H37Rv
Score = 621 bits (1601), Expect = 0.0
Identities = 399/837 (47%), Positives = 439/837 (52%), Gaps = 196/837 (23%)
Query: 1 MSFVVTAPPVLASAASDLGGIASMISEANAMAAVRTTALAPAAADEVSAAIAALFSSYAR 60
MSFV+ AP L + ASDL GI S ++EANA A TTAL A ADEVSAAIAALF ++ +
Sbjct: 1 MSFVIAAPEALVAVASDLAGIGSALAEANAAALAPTTALLAAGADEVSAAIAALFGAHGQ 60
Query: 61 DYQTLSVQVTAFHVQFAQTLTNAGQLYAVVDVGN-GVLLKTEQQVLGVINAPTQTLVGRP 119
YQT+S Q +AFH QF Q LT G YA + N T+Q++L +IN PTQ L+GRP
Sbjct: 61 AYQTVSAQASAFHAQFVQALTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQALLGRP 120
Query: 120 LIGDGTHGAPGTGQNGGAGGILWGNGGNGG-SGAPGQPGGRGGDAGLFGHGGHGGVGGPG 178
LIGDG +G P GQ+GG GG+L+GNGGNGG S G GG GG AGL G+GG GG GG G
Sbjct: 121 LIGDGANGGP--GQDGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIGNGGAGGGGGAG 178
Query: 179 IAGAAGTA--------------------GLPGGNGANGGSGGIGGAGGAGGNGGL----- 213
AG G A G+ GGNG GGS G+ G GGAGG+GG
Sbjct: 179 AAGGNGGAGGWLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGTGGAGGDGGNGRSGP 238
Query: 214 ------------------LFGNGGAGGQGGSGGLGGS----------GGTGGAG------ 239
LFG+ GAGG GG GG GG+ GG GGAG
Sbjct: 239 VNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDGGAGGAGGSGGHA 298
Query: 240 --MAAGPAGGTGGIGGIGGI----------GGAGGVGGHGSALFGHGGINGD-------- 279
AG AGG GG GG GG GGAGG GG G LFG+GG G
Sbjct: 299 LLWGAGGAGGNGGSGGTGGAGGSTAGAGGNGGAGGGGGTGGLLFGNGGAGGHGAAAGNGL 358
Query: 280 --------------GGTGGMGGQGGAGGNGWAAEGITVGIGEQGGQGGDGGAGGAGGIGG 325
GGTGG GG GGAGG G A G+G GG GGDGGAGGAGG GG
Sbjct: 359 AAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNAR--LWGVGGAGGAGGDGGAGGAGGKGG 416
Query: 326 SA------GGIGGSQGAGGHGGDGGQGGA----------GGSGGVGG------------- 356
S GG GG G GG GG GG+GGA GG GG GG
Sbjct: 417 SGLSGNANGGAGGDSGRGGTGGAGGEGGAAGLLVGTGGHGGDGGAGGAAVKGGDGGAAAG 476
Query: 357 -GGAGAGGDGGAGGIGGTGGNG------------SIGGAAGNGGNGGRGGAGGMATA--- 400
G AGAGG GGAGG GG+GG+G GGA GNGG GGAGG A
Sbjct: 477 TGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGGGGG 536
Query: 401 -GSDGGNGGGGGNGGVGV--------GSAGG-------------------AGGTGGDGGA 432
G +GGNGG GGNGG G G AGG GGTGG+GG
Sbjct: 537 NGGNGGNGGNGGNGGNGATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGGGTGGNGGI 596
Query: 433 AGAGGAPGHGYFQQPAPQGLPIGTGGTGGEGGAGGAGGDGGQGDIGF---DGGRGGDGGP 489
G GG+ G G GL +G GG GG G +GGAG GG G GF DGG GGDGG
Sbjct: 597 GGTGGSGGAG-----GNAGL-LGVGGAGGHGASGGAGDRGGAGGTGFISSDGGAGGDGGD 650
Query: 490 GGGGGAGGDGSGTFNAQANN--GGDGGA---GGVGGAGGTGGTGGVGADGGRGGDSGRGG 544
GG GGAGG G F A N GG GGA GG GGAG GGT G G +GG GG +G GG
Sbjct: 651 GGNGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNGGGTDGNGGNGGSGGGAGSGG 710
Query: 545 DGGNAGHGGAAQF--SGRGAYGGEGGSGGAGGNAGGA-GTGGTAGSGGAGGFGGNGADG- 600
DGG AG GA F G G GG+GG+G GG GG+ G G GSGG GG GGNGA G
Sbjct: 711 DGGGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGGDGGDGGNGAPGG 770
Query: 601 ---GNGGNGGNGGFGGINGTFGTNGAGGTGGLG--TLLGGHNGNIGLNGATGGIGST 652
GNGG GG G GGI G T GAGG GG G L G GN G NG GG G T
Sbjct: 771 VLYGNGGAGGQGSSGGIGGPGATGGAGGKGGDGGDAQLIGDGGN-GGNGGAGGTGGT 826
Score = 420 bits (1079), Expect = e-121
Identities = 280/611 (45%), Positives = 309/611 (50%), Gaps = 86/611 (14%)
Query: 197 GSGGIGGAGGAGGNGGLLFGNGGAGGQGGSGGLGGSGGTGGAGMAAGPAGGTGGIGGIGG 256
G G GG G GG GGLL+GNGG GG + G+ G G G AG+ G GG GG GG
Sbjct: 123 GDGANGGPGQDGGPGGLLYGNGGNGGTSTTAGVAGGNG-GAAGLI-----GNGGAGGGGG 176
Query: 257 IGGAGGVGGHGSALFGHGGINGDGGT----GGMGGQGGAGGNGWAAEGITVGIGEQGGQG 312
G AGG GG G L+G+GG G GGT G GG GGAGG+ G+ GG G
Sbjct: 177 AGAAGGNGGAGGWLYGNGGAGGAGGTSVIPGVAGGNGGAGGSA--------GLWGTGGAG 228
Query: 313 GDGGAGGAG--GIGGSAGGIGGSQGAGGHGGDGGQGGAGGSGGVGGGGAG---AGGDGGA 367
GDGG G +G + GSAGG GG+ GA G GD G GG GG GG GG GDGGA
Sbjct: 229 GDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAGGNGGKGGAGGAAFSINFTAGDGGA 288
Query: 368 GGIGGTGGNGSI---GGAAGNGGNGGRGGAGGMATAGSDGGNGGGGGNGGVGVGSAGGAG 424
GG GG+GG+ + GGA GNGG+GG GGAGG +TAG+ GGNGG GG GG G G G G
Sbjct: 289 GGAGGSGGHALLWGAGGAGGNGGSGGTGGAGG-STAGA-GGNGGAGGGGGTG-GLLFGNG 345
Query: 425 GTGGDGGAAGAGGAPGHGYFQQPAPQGLPIGTGGTGGEGGAGGAGGDGGQGDIGFDGGRG 484
G GG G AAG G A G+G G GTGG GG+GGAGGAGG+ +G GG G
Sbjct: 346 GAGGHGAAAGNGLAAGNGVSSSGG--GGAGGTGGAGGDGGAGGAGGNARLWGVGGAGGAG 403
Query: 485 GDGGPGGGGGAGGDG-SGTFNAQANNGGDGGAGGVGGAGGTGG-------TGGVGADGGR 536
GDGG GG GG GG G SG NA GGD G GG GGAGG GG TGG G DGG
Sbjct: 404 GDGGAGGAGGKGGSGLSG--NANGGAGGDSGRGGTGGAGGEGGAAGLLVGTGGHGGDGGA 461
Query: 537 GGDSGRGGDGGNAGHGGAAQFSGRGAYGGEGGSGGAGGNAGGAGTGGTAGSGGAGGFGGN 596
GG + +GGDGG A G A GRG GG GGSGG GG G G GGAGG GG
Sbjct: 462 GGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGGSGGDGGGGAAGPAGWLFGDGGAGGNGGA 521
Query: 597 GADGGNGGN-GGNGGFGGINGTFGTNGAGGTGGLGTLLGGHNGNIGLNGATGGIGSTTLT 655
A GG GG GG GG GG G G G GG G G L G NG G GAT G G
Sbjct: 522 AAAGGAGGQAGGGGGNGGNGGNGGNGGNGGNGATGGWLYG-NGGAGGQGATAGAGGAGAN 580
Query: 656 NATVPLQLVNTTEPVVFISLNGGQMVPVLLDTGSTGLVMDSQFLTQNFGPVIGTGTAGYA 715
+ S NGG TG G + GTG +G A
Sbjct: 581 GVS---------------STNGG-------GTGGNG-------------GIGGTGGSGGA 605
Query: 716 GGLTYNYNTYSTTVDFGNGLLTLPTSVNVVTSSSPGTLGNFLSRSGAVGVLGIGPNNGFP 775
GG N G+G S G G S GA G G G N G
Sbjct: 606 GG---NAGLLGVGGAGGHG-----ASGGAGDRGGAGGTGFISSDGGAGGDGGDGGNGGAG 657
Query: 776 GTSSIVTAMPG 786
GT ++ G
Sbjct: 658 GTGGLLFGAGG 668
Score = 26.6 bits (57), Expect = 0.007
Identities = 40/162 (24%), Positives = 53/162 (32%), Gaps = 37/162 (22%)
Query: 705 PVIGTGTAGYAGGLTYNYNTYSTTVDFGNGLLTLPTSVNVVTSSSPGTLGNFLSRSGAVG 764
P+IG G G G D G G L N TS++ G G GA G
Sbjct: 120 PLIGDGANGGPGQ------------DGGPGGLLYGNGGNGGTSTTAGVAG---GNGGAAG 164
Query: 765 VLGIGP---------------------NNGFPGTSSIVTAMPGLLNNGVLIDESAGILQF 803
++G G NG G + + +PG+ SAG+
Sbjct: 165 LIGNGGAGGGGGAGAAGGNGGAGGWLYGNGGAGGAGGTSVIPGVAGGNGGAGGSAGLWGT 224
Query: 804 GPNTLTGGITISGAPISTVAVQIDNGPLQQAPVMFDSGGING 845
G GG SG P++ NG A +F G G
Sbjct: 225 GGAGGDGGNGRSG-PVNVAGSAGGNGGAGGAAGLFGDAGAGG 265