Pairwise Alignments
Query, 487 a.a., PPE family protein PPE10 from Mycobacterium tuberculosis H37Rv
Subject, 3716 a.a., PPE family protein PPE56 from Mycobacterium tuberculosis H37Rv
Score = 360 bits (925), Expect = e-103
Identities = 200/424 (47%), Positives = 242/424 (57%), Gaps = 48/424 (11%)
Query: 6 FAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAWLGPSA 65
F LPPEINS LM++G GS PL+AAA AW LAEEL ++ S G VTS LT+G W G +A
Sbjct: 3 FPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAA 62
Query: 66 AAMMAVATQYLAWLSTAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAA 125
AAM A A Y WL + AA AE A QA + FEAALAATV PA+VAANR + LA
Sbjct: 63 AAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAV 122
Query: 126 TNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFDASAAVAQLAPWQQVLRNLG------ 179
+N GQN PA+ EA YE MWA DVAAMAGYH ASAA A L + + LG
Sbjct: 123 SNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAF 182
Query: 180 -----------------------------------IDIGKNGQINLGFGNTGSGNIGNNN 204
+ G G NLGFGN G N+G N
Sbjct: 183 LTALFASPAKALSLNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNVGFGN 242
Query: 205 IGNNNIGSGNT-------GTGNIGSGNTGSGNLGLGNLGDGNIGFGNTGSGNIGFGITGD 257
+GN N+G GN+ G GNIG GN GS N G NLG GNIGFGNTG+ N+G G+TG+
Sbjct: 243 LGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVGLTGN 302
Query: 258 HQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSA 317
H G GG NSG+GNIG NSGTGNVG FNSG+GN G+ NSG+ N+G+G +GT + GL +A
Sbjct: 303 HLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGNAGTASTGLFNA 362
Query: 318 GSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQH 377
G+ NT N G N +A + + G TG ++T ++GI S +TG
Sbjct: 363 GNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGAFIS 422
Query: 378 GLAN 381
G N
Sbjct: 423 GNFN 426
Score = 199 bits (505), Expect = 2e-54
Identities = 140/426 (32%), Positives = 204/426 (47%), Gaps = 68/426 (15%)
Query: 20 AGPGSGPLI--AAATAWGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQY-- 75
AGP + P+I AA +G + + S G + G+ +G A + + Q
Sbjct: 1807 AGPLNIPIIDIPAAPGFGNSTQ-----MPSSGFFNTGAGGGSGIGNLGAGVSGLLNQAGA 1861
Query: 76 ------LAWLSTAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAATNWF 129
L+ L A A AI+ F + PAV++ L ++ +
Sbjct: 1862 GSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHMSGVSID 1921
Query: 130 G-------QNAPALMD--VEAAYEQMWALDV--AAMAGYHFDASAAVAQLAPWQQVLRNL 178
G A ++ D ++AA ++ LD+ A G + +A + + N+
Sbjct: 1922 GLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFNLGAGNV 1981
Query: 179 G---IDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGT-------GNIGSGNTGSG 228
G + G G NLG GN G+GN+G NIG N G GN G GN+G GN GSG
Sbjct: 1982 GNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGLGNAGSG 2041
Query: 229 NLGLGNLGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSG 288
+ GL N+G GNIG NTG+GNIG G+TGD++ G GG NSG+GN+G NSGTGN+G FN+G
Sbjct: 2042 SWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNIGFFNTG 2101
Query: 289 SGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSA 348
+GN G+ NSGS ++G+G +GT + GL +AG+ NT NAG
Sbjct: 2102 TGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAG-------------------- 2141
Query: 349 GYATGGMSTAALSSGILASALGSTGGLQHGLANV--LNSGLTNTPVAAPASAPVGGLDSG 406
Y TG ++ + +TGG+ G N N+G TNT + + G +SG
Sbjct: 2142 SYNTGSLNVGSF----------NTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSG 2191
Query: 407 NPNPGS 412
+ N G+
Sbjct: 2192 SFNNGA 2197
Score = 196 bits (499), Expect = 9e-54
Identities = 99/200 (49%), Positives = 121/200 (60%), Gaps = 7/200 (3%)
Query: 186 GQINLGFGNTGSGNIGNNNIGNNNIG-------SGNTGTGNIGSGNTGSGNLGLGNLGDG 238
G NLG GN G GN+G NIG+ N+G +G G GN+G GN G N GL N+G G
Sbjct: 806 GGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVG 865
Query: 239 NIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSG 298
NIGF NTG+GNIG G+ GDH+ G GG NSG GNIG NSGTGNVG FNSG+GN GIGNSG
Sbjct: 866 NIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSG 925
Query: 299 SLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTA 358
N+GIG SGT + GL +AGS +T N G N +A + + G TG +T
Sbjct: 926 RFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTG 985
Query: 359 ALSSGILASALGSTGGLQHG 378
++G+ + TG G
Sbjct: 986 HANTGLANAGTFGTGAFMTG 1005
Score = 193 bits (491), Expect = 8e-53
Identities = 102/205 (49%), Positives = 125/205 (60%), Gaps = 12/205 (5%)
Query: 186 GQINLGFGNTGSGNIGNNNIGNNNIGSGNTGT-------GNIGSGNTGSGNLGLGNLGDG 238
G NLG GN GSGN+G NIG N+G N+G GN+G N GS N GL NLG G
Sbjct: 1393 GAQNLGLGNLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVG 1452
Query: 239 NIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSG 298
NIG NTG+GNIG G+ GD+Q G GG NSGSGNIG NSGTGNVG FN+G+GN G+ NSG
Sbjct: 1453 NIGLANTGTGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSG 1512
Query: 299 SLNSGIGTSGTINAGLGSAGSLNTSF-----WNAGMQNAALGSAAGSEAALVSSAGYATG 353
S N+GIG SGT + GL +AG+ NT +N G N + G +++ + TG
Sbjct: 1513 SFNTGIGNSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWFNTG 1572
Query: 354 GMSTAALSSGILASALGSTGGLQHG 378
M+T ++G L S S G L G
Sbjct: 1573 IMNTGTRNTGALMSGTDSNGMLWRG 1597
Score = 193 bits (491), Expect = 8e-53
Identities = 96/200 (48%), Positives = 128/200 (64%), Gaps = 12/200 (6%)
Query: 186 GQINLGFGNTGSGNIGNNNIGNNNIGSGNTGT-------GNIGSGNTGSGNLGLGNLGDG 238
G NLGFGN G+GN+G NIG+ N+G GN+G GN+G GN G N GL N+G G
Sbjct: 3173 GAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGLANVGVG 3232
Query: 239 NIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSG 298
NIG NTG+GNIG G+TGD+Q G GG NSG+GN+G NSG GNVG FN+G+GN G+ NSG
Sbjct: 3233 NIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSG 3292
Query: 299 SLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTA 358
S N+G+G SGT + GL +AGS NT NAG N + + ++ G+ G ++T
Sbjct: 3293 SFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDT-----NTGGFNPGSINTG 3347
Query: 359 ALSSGILASALGSTGGLQHG 378
L++G + + + G + G
Sbjct: 3348 WLNAGNANTGVANAGNVNTG 3367
Score = 191 bits (485), Expect = 4e-52
Identities = 100/200 (50%), Positives = 120/200 (60%), Gaps = 7/200 (3%)
Query: 186 GQINLGFGNTGSGNIGNNNIGNNNIGSGNTGT-------GNIGSGNTGSGNLGLGNLGDG 238
G NLG GN G+GN+G N+G+ NIG GN+G GN G GN GS N G N G
Sbjct: 2586 GAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLGNTGFGNAGSANYGFANQGVR 2645
Query: 239 NIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSG 298
NIG NTG+GNIG G+ GD+ G GG NSG+GNIG NSGTGN+G FNSG+GN GIGNSG
Sbjct: 2646 NIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNFGIGNSG 2705
Query: 299 SLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTA 358
S N+GIG SGT + GL +AGS NT NAG N +A + + TG +T
Sbjct: 2706 SFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNAGDTNTGGFNPGTINTGWFNTG 2765
Query: 359 ALSSGILASALGSTGGLQHG 378
++GI S TG G
Sbjct: 2766 HTNTGIANSGNVGTGAFMSG 2785
Score = 155 bits (391), Expect = 3e-41
Identities = 107/281 (38%), Positives = 138/281 (49%), Gaps = 43/281 (15%)
Query: 177 NLGIDIGKNGQINLGFGNTGS-------GNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGN 229
NLG G G N+G GN+G GN+G N G NN G N G GNIG NTG+GN
Sbjct: 3186 NLGF--GNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGN 3243
Query: 230 LGLG------------NLGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNS 277
+G+G N G GN+G N+G+GN+GF TG FG FNSGS N G GNS
Sbjct: 3244 IGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTG--NFGLFNSGSFNTGVGNS 3301
Query: 278 GTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSA 337
GTG+ GLFN+GS N G+ N+GS N+G G N G + GS+NT + NAG N + +A
Sbjct: 3302 GTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANA 3361
Query: 338 AGSEAALVSSAGYATGGMSTAAL----SSGILASALGSTGGLQHGLANVLNSGLTNTPVA 393
V++ + TG S L G+ A+G T L + ++ G+ V
Sbjct: 3362 GN-----VNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVL 3416
Query: 394 APASAPVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPS 434
P P P P +A G G + P S PS
Sbjct: 3417 PPIHIP--------PIPVGFAAVGGIGP---IAIPDISVPS 3446
Score = 151 bits (381), Expect = 4e-40
Identities = 100/299 (33%), Positives = 145/299 (48%), Gaps = 53/299 (17%)
Query: 179 GIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDG 238
G + ++ +N+G+ + G+ N G N+G+ N G+ N G N+G GN GSGN+G GN+G G
Sbjct: 1356 GTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGNLGSGNVGFGNIGAG 1415
Query: 239 NIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSG 298
N+GF N+G G+ G +G N+GS N G N G GN+GL N+G+GNIGIG G
Sbjct: 1416 NVGFANSGPA---VGLAGLGNVGLS--NAGSNNWGLANLGVGNIGLANTGTGNIGIGLVG 1470
Query: 299 SLNSGIG--TSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMS 356
+GIG SG+ N GL ++G+ N F+N G N L +
Sbjct: 1471 DYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGL--------------------FN 1510
Query: 357 TAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAA 416
+ + ++GI S GSTG + N+G NT +A P S G + G+ N G
Sbjct: 1511 SGSFNTGIGNSGTGSTG--------LFNAGNFNTGIANPGSYNTGSFNVGDTNTG----- 1557
Query: 417 AGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAY 475
G NPG +N+G ++G+ NT R SG + D E +
Sbjct: 1558 ---GFNPG----------DINTGWFNTGIMNTGTRNTGALMSGTDSNGMLWRGDHEGLF 1603
Score = 150 bits (378), Expect = 1e-39
Identities = 89/205 (43%), Positives = 116/205 (56%), Gaps = 20/205 (9%)
Query: 177 NLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLG--N 234
N G+ G G N+G GN GSG+ G N+G NIG NTGTGNIG G TG G+G N
Sbjct: 2020 NAGLTAGAGGLGNVGLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLN 2079
Query: 235 LGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGI 294
G GN+G N+G+GNIGF TG FG FNSGS + G GN+GT + GLFN+G+ N G+
Sbjct: 2080 SGTGNLGLFNSGTGNIGFFNTGTG--NFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGL 2137
Query: 295 GNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGG 354
N+GS N+G G+ N G + G++NT ++N G N L + TG
Sbjct: 2138 ANAGSYNTGSLNVGSFNTGGVNPGTVNTGWFNTGHTNTGL---------------FNTGN 2182
Query: 355 MSTAALSSGILASALGSTGGLQHGL 379
++T A +SG + TG HGL
Sbjct: 2183 VNTGAFNSGSFNNGALWTGD-YHGL 2206
Score = 149 bits (377), Expect = 1e-39
Identities = 124/379 (32%), Positives = 173/379 (45%), Gaps = 46/379 (12%)
Query: 34 WGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQYLAWLSTAAAQAEQAAAQA 93
W + LL + + +G+V + L SG L + T L + + AA Q
Sbjct: 704 WNQAPSALLGAGSGVGNVGT-LGSGV-LNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQ 761
Query: 94 MAIATAFEAALAATVQPAVVAANRGLMQLLAATNWFGQNAPALMDVEAAYEQMWALDVAA 153
++ +A A T +++A N GL + FG + DV L A
Sbjct: 762 LSGVSA-----AGTTLRSMLAGNLGLANVGNFNTGFGN----VGDVN--------LGAAN 804
Query: 154 MAGYHF------DASAAVAQLAPWQQVLRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGN 207
+ G++ D + + + NLG+ G G N+GFGN G N G N+G
Sbjct: 805 IGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGV 864
Query: 208 NNIGSGNTGTGNIGSGNTGSGNLGLG--NLGDGNIGFGNTGSGNIGFGITGDHQMGFGGF 265
NIG NTGTGNIG G G G+G N G GNIG N+G+GN+GF +G G G
Sbjct: 865 GNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIG-- 922
Query: 266 NSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFW 325
NSG N G GNSGT + GLFN+GS + GI N+G N+G +G N G + G +NT ++
Sbjct: 923 NSGRFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWF 982
Query: 326 NAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANV-LN 384
N G N L +A + TG T S+G+L GG + GL V +
Sbjct: 983 NTGHANTGLANA----------GTFGTGAFMTGDYSNGLL-----WRGGYE-GLVGVRVG 1026
Query: 385 SGLTNTPVAAPASAPVGGL 403
++ PV A VG L
Sbjct: 1027 PTISQFPVTVHAIGGVGPL 1045
Score = 149 bits (377), Expect = 1e-39
Identities = 100/286 (34%), Positives = 138/286 (48%), Gaps = 48/286 (16%)
Query: 182 IGKNGQINLGFGNTGS-------GNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGN 234
IG GQ G G+ GN+G N+GN N G GN G N+G+ N G NLGLGN
Sbjct: 755 IGNLGQQLSGVSAAGTTLRSMLAGNLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGN 814
Query: 235 LGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGI 294
+GDGN+G GN G GN+GF +G +G GN+GFGN+G N GL N G GNIG
Sbjct: 815 VGDGNLGLGNIGHGNLGFA-----NLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGF 869
Query: 295 GNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGG 354
N+G+ N GIG G G+G LN+ N G+ N+ G+ G+ G
Sbjct: 870 ANTGTGNIGIGLVGDHRTGIGG---LNSGIGNIGLFNSGTGNV-----------GFFNSG 915
Query: 355 MSTAAL-SSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSG 413
+ +SG + +G++G GL N+G +T +A G ++G+ N G
Sbjct: 916 TGNFGIGNSGRFNTGIGNSGTASTGL---FNAGSFSTGIANTGDYNTGSFNAGDTNTG-- 970
Query: 414 SAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSG 459
G NPG +N+G ++G NT + T G+G
Sbjct: 971 ------GFNPG----------GINTGWFNTGHANTGLANAGTFGTG 1000
Score = 149 bits (377), Expect = 1e-39
Identities = 91/232 (39%), Positives = 124/232 (53%), Gaps = 29/232 (12%)
Query: 160 DASAAVAQLAPWQQVLRNLG---IDIGKNGQINLGFGNTGS-------GNIGNNNIGNNN 209
D + A L L N+G + G N+GFGN+G GN G N G+ N
Sbjct: 2577 DVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLGNTGFGNAGSAN 2636
Query: 210 IGSGNTGTGNIGSGNTGSGNLGLGNLGDGNIGFG--NTGSGNIGFGITGDHQMGFGGFNS 267
G N G NIG NTG+GN+G+G +GD G G N+G+GNIG FNS
Sbjct: 2637 YGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGL------------FNS 2684
Query: 268 GSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNA 327
G+GNIGF NSGTGN G+ NSGS N GIGNSG+ ++G+ +G+ N G+ +AGS NT +NA
Sbjct: 2685 GTGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNA 2744
Query: 328 GMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGL 379
G N G +++ + TG +T +SG + + +G +GL
Sbjct: 2745 GDTN-----TGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGL 2791
Score = 134 bits (338), Expect = 4e-35
Identities = 102/303 (33%), Positives = 143/303 (47%), Gaps = 20/303 (6%)
Query: 171 WQQV---LRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGN--TGTGNIGSGNT 225
W Q L G G ++ G N GSG G N +G+ +G GN+G +
Sbjct: 3071 WNQAHTALAGAGSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLS 3130
Query: 226 G--SGNLGLGNLGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVG 283
G SG + + NIG N GS N GFG G+ + G N G+ N+GFGN G GN+G
Sbjct: 3131 GLLSGGSAVNPVTVLNIGLANVGSHNAGFGNVGE--VNLGAANLGAHNLGFGNIGAGNLG 3188
Query: 284 LFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAA 343
N G GN+G+GNSG L +G+ G N GLG+AG N N G+ N L +
Sbjct: 3189 FGNIGHGNVGVGNSG-LTAGVPGLG--NVGLGNAGGNNWGLANVGVGNIGLANTGTGNIG 3245
Query: 344 LVSSAGYATG--GMSTAALSSGILASALGSTGGLQHGLAN--VLNSGLTNTPVAAPASAP 399
+ + Y TG G+++ A + G+ S G+ G G N + NSG NT V +
Sbjct: 3246 IGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSGSFNTGVGNSGTGS 3305
Query: 400 VGGLDSGNPNPG---SGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTP 456
G ++G+ N G +GS GS N G + G P +N+G ++G NT V
Sbjct: 3306 TGLFNAGSFNTGVANAGSYNTGS-FNVGDTNTGGFNPGSINTGWLNAGNANTGVANAGNV 3364
Query: 457 GSG 459
+G
Sbjct: 3365 NTG 3367
Score = 104 bits (260), Expect = 5e-26
Identities = 91/278 (32%), Positives = 126/278 (45%), Gaps = 43/278 (15%)
Query: 200 IGNNNI----GNNNIGSGN-TGTGNIGSGNTGSGNLGLGNLGDGNIGFGNTG---SG--N 249
IGN+ I G N G+G +G GN G+G +G N L GF N G SG N
Sbjct: 3038 IGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFANVGTLHSGVLN 3097
Query: 250 IGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSG-------NIGIGNSGSLNS 302
+G G++G + G + + G GN G GL + GS NIG+ N GS N+
Sbjct: 3098 LGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLLSGGSAVNPVTVLNIGLANVGSHNA 3157
Query: 303 GIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSS 362
G G G +N G + G+ N F N G N G+ G+ G+ + L++
Sbjct: 3158 GFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNI-----------GHGNVGVGNSGLTA 3206
Query: 363 GILASA---LGSTGGLQHGLANVL--NSGLTNTP-------VAAPASAPVGGLDSGNPNP 410
G+ LG+ GG GLANV N GL NT + +GGL+SG N
Sbjct: 3207 GVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNL 3266
Query: 411 GSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNT 448
G ++ AG N G + GT NSGS ++G+ N+
Sbjct: 3267 GLFNSGAG---NVGFFNTGTGNFGLFNSGSFNTGVGNS 3301
Score = 100 bits (249), Expect = 9e-25
Identities = 90/300 (30%), Positives = 124/300 (41%), Gaps = 38/300 (12%)
Query: 191 GFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNIGFGNTGSGNI 250
GF NTG G G N+G+G +G N G G+ N G + G N GSG
Sbjct: 1268 GFFNTGGGG----GSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGIS 1323
Query: 251 GFGITGDHQMGFGGFNSGSGNIGFGNSG------------TGNVGLFNSGSGNIGIGNSG 298
G+ T G SG GN+G SG N+G + G+ N G+GN G
Sbjct: 1324 GWYNTSTLGAGTPAVVSGIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVG 1383
Query: 299 SLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTA 358
LN G G N GLG+ GS N F N G N ++ + V AG G+S A
Sbjct: 1384 DLNWGAANIGAQNLGLGNLGSGNVGFGNIGAGNVGFANSGPA----VGLAGLGNVGLSNA 1439
Query: 359 ALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAG 418
G GLAN+ G+ N +A + +G G+ G G +G
Sbjct: 1440 --------------GSNNWGLANL---GVGNIGLANTGTGNIGIGLVGDYQTGIGGLNSG 1482
Query: 419 SGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASP 478
SG N GL + GT F N+G+ + GL N+ SG + + + + + A+P
Sbjct: 1483 SG-NIGLFNSGTGNVGFFNTGTGNFGLFNSGSFNTGIGNSGTGSTGLFNAGNFNTGIANP 1541
Score = 94.0 bits (232), Expect = 8e-23
Identities = 99/321 (30%), Positives = 134/321 (41%), Gaps = 77/321 (23%)
Query: 191 GFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNL-GLGNLGDGNIGFGNTGSG- 248
GF NTG+G G + IGN +G+G +G N + G L GLGN G G N+G+
Sbjct: 1833 GFFNTGAG--GGSGIGN--LGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAI 1888
Query: 249 ----NI------------GFGITGDHQMGFG--GF------------------------- 265
N+ GF GDH G G
Sbjct: 1889 SGLFNVSTLDATTPAVISGFSNLGDHMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQ 1948
Query: 266 NSGSGN-IGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSF 324
+ GN + GN G N+GL N G N+G GN G++N G G G N GLG+ G+ N F
Sbjct: 1949 HLDIGNALALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGF 2008
Query: 325 WNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLN 384
N G N G+A L + AG G+ LG+ G GLANV
Sbjct: 2009 GNIGAGNFGFGNAG-----LTAGAG-------------GLGNVGLGNAGSGSWGLANV-- 2048
Query: 385 SGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSG 444
G+ N +A + +G +G+ G G +G+G N GL + GT F N+G+ + G
Sbjct: 2049 -GVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTG-NLGLFNSGTGNIGFFNTGTGNFG 2106
Query: 445 LRN-----TAVREPSTPGSGI 460
L N T V T +G+
Sbjct: 2107 LFNSGSYSTGVGNAGTASTGL 2127
Score = 79.3 bits (194), Expect = 2e-18
Identities = 65/200 (32%), Positives = 88/200 (44%), Gaps = 42/200 (21%)
Query: 266 NSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFW 325
N+G GN+G N G GNVG+FN +G GN G N G G +G N G G+ G+ N F
Sbjct: 197 NAGLGNVGNYNVGLGNVGVFN-----LGAGNVGGQNLGFGNAGGTNVGFGNLGNGNVGFG 251
Query: 326 NAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLNS 385
N+G+ AG A G+ LG+ G +G AN+
Sbjct: 252 NSGL-----------------GAGLA-----------GLGNIGLGNAGSSNYGFANL--- 280
Query: 386 GLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSN---- 441
G+ N + VG +GN G G +G+G N GL + GT F NSG+
Sbjct: 281 GVGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTG-NIGLFNSGTGNVGFFNSGTGNFGV 339
Query: 442 -DSGLRNTAVREPSTPGSGI 460
+SG NT V T +G+
Sbjct: 340 FNSGNYNTGVGNAGTASTGL 359
Score = 75.1 bits (183), Expect = 4e-17
Identities = 69/219 (31%), Positives = 92/219 (42%), Gaps = 27/219 (12%)
Query: 241 GFGNTGSG-NIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGS 299
GFGNT + + GF TG G G GF N G G G +N G + SG
Sbjct: 1257 GFGNTTTAPSSGFFNTG-----------GGGGSGFANVGAGTSGWWNQGHDVLAGAGSGV 1305
Query: 300 LNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGG----- 354
N+G +SG +N G G +G NTS AG A+ S G+ +S G+ G
Sbjct: 1306 ANAGTLSSGVLNVGSGISGWYNTSTLGAG--TPAVVSGIGNLGQQLS--GFLANGTVLNR 1361
Query: 355 ---MSTAALSSGILASALGSTGGLQHGLANV--LNSGLTNTPVAAPASAPVGGLDSGNPN 409
++ G + LG+ G L G AN+ N GL N +G + G N
Sbjct: 1362 SPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGNLGSGNVGFGNIGAGNVGFAN 1421
Query: 410 PGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNT 448
G AG G N GL + G++ N G + GL NT
Sbjct: 1422 SGPAVGLAGLG-NVGLSNAGSNNWGLANLGVGNIGLANT 1459
Score = 73.6 bits (179), Expect = 1e-16
Identities = 73/264 (27%), Positives = 105/264 (39%), Gaps = 69/264 (26%)
Query: 263 GGFNSGSGNI-GFGNSGTGNVGLFN----------SGSGNI------------------- 292
G FNSG+G + GFGN G G+ G +N SG GN+
Sbjct: 681 GFFNSGAGGVSGFGNVGAGSSGWWNQAPSALLGAGSGVGNVGTLGSGVLNLGSGISGFYN 740
Query: 293 -------------GIGNSGSLNSGIGTSGTI-------NAGLGSAGSLNTSFWNAGMQNA 332
GIGN G SG+ +GT N GL + G+ NT F N G N
Sbjct: 741 TSVLPFGTPAAVSGIGNLGQQLSGVSAAGTTLRSMLAGNLGLANVGNFNTGFGNVGDVNL 800
Query: 333 ALGSAAGSEAAL---------VSSAGYATGGMSTAALSSGILASALGSTGGLQHGLAN-- 381
+ G L + + G+ G + L++G A+ +G+ G G+ N
Sbjct: 801 GAANIGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAG--AAGVGNVGFGNAGINNYG 858
Query: 382 VLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGS- 440
+ N G+ N A + +G G+ G G +G G N GL + GT F NSG+
Sbjct: 859 LANMGVGNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIG-NIGLFNSGTGNVGFFNSGTG 917
Query: 441 ----NDSGLRNTAVREPSTPGSGI 460
+SG NT + T +G+
Sbjct: 918 NFGIGNSGRFNTGIGNSGTASTGL 941
Score = 45.8 bits (107), Expect = 3e-08
Identities = 41/107 (38%), Positives = 48/107 (44%), Gaps = 18/107 (16%)
Query: 241 GFGNTGSGNIGFGITGDHQMGFGGFNSGSGN-IGFGNSGTGNVGLFN----------SGS 289
GFG G GFG G FN+G+G GF N+G G GL N SG
Sbjct: 3608 GFG----GAPGFG-NSTTLPSSGFFNTGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGF 3662
Query: 290 GNIGIGNSGSLNSGIGTSGTINAG-LG-SAGSLNTSFWNAGMQNAAL 334
N G SG LN G G SG N G LG ++ + F N G Q + L
Sbjct: 3663 ANFGTQLSGILNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGL 3709
Score = 39.7 bits (91), Expect = 2e-06
Identities = 63/212 (29%), Positives = 90/212 (42%), Gaps = 36/212 (16%)
Query: 278 GTGNVGL--FNSGSGNIGIGNSGSLNSGIGTSG----TINAGLGS-------AGSLNTSF 324
GT +G+ ++ GS + +G L G GTS TI+A G+ G + F
Sbjct: 2908 GTNGLGITFYSFGSADGSPYATGPLVFGAGTSDGSHLTISASSGAFTTPQLETGPITLGF 2967
Query: 325 WNAGMQNA------ALGSAAGSEAALVSSAGYATGGMSTAALS-SGILASALGSTGGLQH 377
G NA L A S L +AG GG+ A++ I ASA GS L
Sbjct: 2968 QVPGSVNAITLFPGGLTFPATSLLNLDVTAG--AGGVDIPAITWPEIAASADGSVYVLAS 3025
Query: 378 GLANVL---NSGLTN---TPVAAPASAPVGGLDSGNPNPGSGSAA-------AGSGANPG 424
+ + G+ N TP + +A GG SG N G+G++ A +GA G
Sbjct: 3026 SIPLINIPPTPGIGNSTITPSSGFFNAGAGG-GSGFGNFGAGTSGWWNQAHTALAGAGSG 3084
Query: 425 LRSPGTSYPSFVNSGSNDSGLRNTAVREPSTP 456
+ GT + +N GS SG+ NT+ TP
Sbjct: 3085 FANVGTLHSGVLNLGSGVSGIYNTSTLGVGTP 3116
Score = 32.7 bits (73), Expect = 2e-04
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 388 TNTPVAAPASAPVGGLDSGNPNPGSGSA-------AAGSGANPGLRSPGTSYPSFVNSGS 440
T P + ++ GG+ SG N G+GS+ +A GA G+ + GT +N GS
Sbjct: 675 TTAPSSGFFNSGAGGV-SGFGNVGAGSSGWWNQAPSALLGAGSGVGNVGTLGSGVLNLGS 733
Query: 441 NDSGLRNTAVREPSTPGS 458
SG NT+V TP +
Sbjct: 734 GISGFYNTSVLPFGTPAA 751
Score = 31.2 bits (69), Expect = 7e-04
Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 388 TNTPVAAPASAPVGGLDSGNPNPGSG------SAAAGS--GANPGLRSPGTSYPSFVNSG 439
T P + + GG SG N G+G A AGS G GL + GT +NSG
Sbjct: 1827 TQMPSSGFFNTGAGG-GSGIGNLGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSG 1885
Query: 440 SNDSGLRNTAVREPSTP 456
+ SGL N + + +TP
Sbjct: 1886 TAISGLFNVSTLDATTP 1902
Score = 27.3 bits (59), Expect = 0.010
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 10/62 (16%)
Query: 399 PVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGS 458
P G + P SG +G+G G F N GSN SG N A + GS
Sbjct: 2447 PTPGFGNTTATPSSGFFNSGAGGVSG----------FGNVGSNLSGWWNQAASALAGSGS 2496
Query: 459 GI 460
G+
Sbjct: 2497 GV 2498
Score = 27.3 bits (59), Expect = 0.010
Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 26/105 (24%)
Query: 345 VSSAGYATG-GMSTAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGL 403
++ G A G G ST SSG + G GG SG +NT A + GL
Sbjct: 3606 IAGFGGAPGFGNSTTLPSSGFFNTGAG--GG----------SGFSNT------GAGMSGL 3647
Query: 404 DSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNT 448
+ +P GSA+ G + GT +N G+ SG+ NT
Sbjct: 3648 LNAMSDPLLGSAS-------GFANFGTQLSGILNRGAGISGVYNT 3685