Pairwise Alignments
Query, 966 a.a., Probable conserved transmembrane transport protein MmpL11 from Mycobacterium tuberculosis H37Rv
Subject, 964 a.a., Probable conserved transmembrane transport protein MmpL5 from Mycobacterium tuberculosis H37Rv
Score = 79.0 bits (193), Expect = 1e-18
Identities = 55/219 (25%), Positives = 100/219 (45%), Gaps = 33/219 (15%)
Query: 510 VGGPTALIKDFDDRVSATQPLVLVFVAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYG 569
+GG A+ KD D + + + + F+++LI+ RSV A V +LS+ A++G
Sbjct: 758 LGGTAAMFKDLSDGNTYDLMIAGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFG 817
Query: 570 SLVMVFQWGWARGLGFPALHSIDSTVPPLVLAMT----FGLSMDYEIFLLTRIRERF--- 622
V+++Q H + + LVLAM + DY + L+ R++E
Sbjct: 818 LSVLIWQ------------HILGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAG 865
Query: 623 LQTGQTRDAVAYGVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATV 682
+ TG R + S +T+A L+ FA + + ++A++G + + D +
Sbjct: 866 INTGIIR-----AMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLI 920
Query: 683 VRLVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPK 721
VR + P++ A+ +W WW P V RP+P+
Sbjct: 921 VRSFMTPSIAALLGKWFWW---------PQVVRQRPIPQ 950
Score = 75.5 bits (184), Expect = 2e-17
Identities = 68/274 (24%), Positives = 118/274 (43%), Gaps = 30/274 (10%)
Query: 112 QPDRPYVVSLR------LDARNAGTSDVAKKLRDRIGVKGDQSGQTANGKV--------- 156
Q D +V SL+ L A A +SD K ++ + G+Q AN V
Sbjct: 117 QADTTHVQSLQDFWGDPLTATGAQSSD-GKAAYVQVKLAGNQGESLANESVEAVKTIVER 175
Query: 157 -------RLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFGSLAAAAIPLAL 209
++YV G AL A + E +I+++L+ V+ S+ +AI L +
Sbjct: 176 LAPPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTM 235
Query: 210 AVCTVVITMGLVFVLSMHTT--MSVFVTSTVSMFGIALAVDYSLFILMRYREELRCGRRP 267
V ++ T G V L H +S F T+ + + IA A DY++F++ RY+E G+
Sbjct: 236 VVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDR 295
Query: 268 PDAVDAAMATSGLAVVLSGMTVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTP 327
A + V+ SG+T+ + + P +++ + + + + + TL P
Sbjct: 296 ESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAAALTLGP 355
Query: 328 AVLATFAR----AAAKRSALVH-WSRRPASTQSW 356
A++A +R KR A V W + A+ W
Sbjct: 356 AIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRW 389
Score = 58.5 bits (140), Expect = 2e-12
Identities = 57/248 (22%), Positives = 111/248 (44%), Gaps = 17/248 (6%)
Query: 467 ADDNGSALLSAVLSVDPEDLGARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRV 524
+ D +A + L+ + + A +++ ++T + R+A +V V G AL+ D
Sbjct: 141 SSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERLAPPPGVKVYVTGSAALVADQQQAG 200
Query: 525 SATQPLVLVFVAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG 584
+ ++ + +MLL+ RS+ + + M +L + A G + LG
Sbjct: 201 DRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGLLATRGGVAF---------LG 251
Query: 585 FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAYGV--RTSART 642
F + + + L++ + + DY IFL+ R +E GQ R++ Y + T+
Sbjct: 252 FHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEA-RGLGQDRESAYYTMFGGTAHVV 310
Query: 643 ITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVRLVLVPALMAMFDRWNWWL 702
+ S I A FC +F +P +GV A+ + + L L PA++A+ R+ L
Sbjct: 311 LGSGLTIAGATFC-LSFTRLPYFQTLGVPLAIGMVI-VVAAALTLGPAIIAVTSRFGKLL 368
Query: 703 -PRWLAHI 709
P+ +A +
Sbjct: 369 EPKRMARV 376
Score = 47.8 bits (112), Expect = 4e-09
Identities = 54/264 (20%), Positives = 108/264 (40%), Gaps = 38/264 (14%)
Query: 128 AGTSDVAK-KLRDRIGVKGDQSGQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNL 186
AG + +AK K + +KG +A +Y+ G A+ + +D+ A L
Sbjct: 730 AGIARIAKIKTAAKEAIKGTPLEGSA-----IYLGGTAAMFKDLSDGNTYDLMIAGISAL 784
Query: 187 PIILMVLVAVFGSLAAAAIPLALAVCTVVITMGLVFVLSMHTT---MSVFVTSTVSMFGI 243
+I ++++ S+ AAA+ + V ++ + GL ++ H + V + + +
Sbjct: 785 CLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAVIILL 844
Query: 244 ALAVDYSLFILMRYREELRCGRRPPDAVDAAMATSGLAVVLSGMTVIASLTGIYLINTPA 303
A+ DY+L ++ R +EE+ G + AM SG V +G+ ++ +
Sbjct: 845 AVGADYNLLLVARLKEEIHAGIN--TGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTV 902
Query: 304 LRSMATGAILAVAV-AMLTSATLTPAVLATFARAAAKRSALVHWSRRPASTQSWFWSRWV 362
+ + T + + ++ + +TP++ A + WFW W
Sbjct: 903 MAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGK--------------------WFW--WP 940
Query: 363 GWVMRR----PWITALAASTVLLV 382
V +R PW + +A T LV
Sbjct: 941 QVVRQRPIPQPWPSPASARTFALV 964