Pairwise Alignments

Query, 400 a.a., bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase from Methanococcus maripaludis S2

Subject, 253 a.a., Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) from Sphingobium sp. HT1-2

 Score = 70.9 bits (172), Expect = 4e-17
 Identities = 63/227 (27%), Positives = 103/227 (45%), Gaps = 20/227 (8%)

Query: 3   ILTVGGFDPTGGAGIVADVKTIKELQNNPLSIITSIIPQNNNKVFLKKDLSKEEIKAQFD 62
           IL + G D  GGAGI AD+KT+  L  + ++ IT+I  QN   V     +  E + AQ +
Sbjct: 6   ILIIAGSDSGGGAGIQADIKTVTLLGGHAMTAITAITAQNTLGVQGVHPVPTEMVLAQME 65

Query: 63  AIFEDFNVNWVKTGVLTTDSIDILLEFKKKY--EFNIICDPVLKSTTDFEFSDDFLNKKY 120
           +   D  V+ VK G++ +      +  +        I+ DPV+ +T+    +DD     +
Sbjct: 66  SCISDIGVDAVKIGMIGSAQTAAAVSERLSLLAHVPIVFDPVMVATSGSLLADDATIAAF 125

Query: 121 FEFFKECFLITPNLKEF-----EIIKKMFET---SKSNLNDINVL---VTGKTDVLKI-D 168
                   L+TPN+ E      E I   F T   +K    +  +L   + G   V K   
Sbjct: 126 ERLMAIATLVTPNIPELAALGGEEIAIRFVTHVLAKGGHGEGPMLTDRLIGPQGVRKAWS 185

Query: 169 NKNIEITGKYVEKEVHGTGCTYSSAITCFLSNGMTVKDSIVSAKEFV 215
           N  I+       +  HGTGCT +SAI   L  G+ + +++   +++V
Sbjct: 186 NARID------TRHSHGTGCTLASAIATGLGQGLDLIEAVERGRKYV 226