Pairwise Alignments

Query, 416 a.a., histidine--tRNA ligase from Methanococcus maripaludis S2

Subject, 429 a.a., histidinol dehydrogenase from Pseudomonas simiae WCS417

 Score =  149 bits (377), Expect = 1e-40
 Identities = 118/423 (27%), Positives = 191/423 (45%), Gaps = 32/423 (7%)

Query: 3   QKPKGTRDFLPEEMKKRKTIEKKLRKVFDSYNFSEINTPTFESFELLSKKTG---DEIRT 59
           Q  +G  D LPE+    +  E  + ++ D+Y + +I  P  E  EL  +  G   D +  
Sbjct: 6   QAIRGMNDILPEQTPLWRYFEGTVARLLDNYGYKQIRMPIVEFTELFKRSIGEVTDIVEK 65

Query: 60  QLFVFRDHGDREMGLRPELTSSVARFYINE-FKNTPKPVKLYYFTNCFRYENPQAGRYRE 118
           +++ F D     + LRPE T++  R  +        +P KL+Y    FR+E PQ GRYR+
Sbjct: 66  EMYTFEDRNGDSLTLRPEGTAACVRAVLEHGLTGAGQPQKLWYIGPMFRHERPQKGRYRQ 125

Query: 119 FWQMGSELIGSKKPIADAEVVNMA--IEGLKEINMDFEIHIGHLGVLKGVFEKYNLSDDE 176
           F Q+G E+     P  DAE++ +   + GL  I    ++ +  LG           S+  
Sbjct: 126 FHQIGLEVFNIDGPDIDAELIVLTWRLWGLLGIRDAVKLELNSLGT----------SESR 175

Query: 177 GNEIRRLIDKEDMDGLKSVLSRLESEKNIEISKKVFEVLDLKGGK-EVIPILKEKLADF- 234
           G     L++      L + L +L+ +    +      VLD K    + + +   K+AD+ 
Sbjct: 176 GRYKVALVEY-----LSAHLDKLDEDSQRRLKTNPLRVLDTKNADTQAVLVNAPKMADYL 230

Query: 235 -ESSVAALENLDSILEFVPHDYVINFGIARGLDYYTGMVFEVYGKKEGAK-QVCGGGRYD 292
            + S    E L + LE     + IN  + RGLDYY+  VFE    K GA+  VC GGRYD
Sbjct: 231 DDESRIHFEGLKARLEAAGIPFEINTKLVRGLDYYSKTVFEWVTDKLGAQGTVCAGGRYD 290

Query: 293 NLIELFEGEPSPAVGFAYGFDRIMLNIDDFEVENESIF----VVPVKSSEMLLKECLKIA 348
            L+E   G+P+  VGFA G +R++L ++  E   E I     V      E      L ++
Sbjct: 291 GLVEQMGGKPTTGVGFAMGIERLILLLETLEKVPEEISRQVDVYLCAFGEAAELAALALS 350

Query: 349 KTLRDS--GKSVEVDLMGRKLNKALNYANTKNIKKVLIVGENDIRDGKVSLKNME-TGEQ 405
           + +RD      ++V+            A+       LI+G++++    +  K +   GEQ
Sbjct: 351 EKVRDQLPNLRLQVNAGAGSFKSQFKKADKSGALYALILGDDELAQQVIGFKPLRGQGEQ 410

Query: 406 SLI 408
             I
Sbjct: 411 QNI 413