Pairwise Alignments

Query, 396 a.a., bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC from Methanococcus maripaludis S2

Subject, 406 a.a., fused 4'-phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase, FMN-binding from Escherichia coli BL21

 Score =  131 bits (330), Expect = 3e-35
 Identities = 108/393 (27%), Positives = 194/393 (49%), Gaps = 38/393 (9%)

Query: 15  LDGKKLVVAVTSSIAAIEAPRLMRELIRHGAEVYCIMTEETKDIVGKYSLEFGCGNEVMD 74
           L GKK+V+ V+  IAA + P L+R L   GA+V   MTE  K  +   SL+   G  V D
Sbjct: 3   LAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSD 62

Query: 75  KI-----TGKIEHVDLYNKCDGMIVFPATANIISKISLNIADNIVNTTAMMFLEKKPIII 129
            +        + H++L    D +I+ PATA++I++++  +A+++V+T  +      P+ +
Sbjct: 63  SLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGMANDLVSTICL--ATPAPVAV 120

Query: 130 APSMHQNML-DTVRDHIKNLSEKNNVFVMGSKMEEEKAKAIS----IDEVS--KLAIDVF 182
            P+M+Q M       H   +     + + G     +    I     +D ++   +A+  F
Sbjct: 121 LPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGDIGPGRMLDPLTIVDMAVAHF 180

Query: 183 SDRKE-ERKKVLILSGGTAEPIDKVRVITNLSSGKTGVSLAEEFCRQNYDVDVIKG-LGK 240
           S   + +   ++I +G T EP+D VR I+N SSGK G ++A    R+  +V ++ G +  
Sbjct: 181 SPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSGPVSL 240

Query: 241 DVPYYINSENVITSQEMLKKALELGESADIIISCAAISDYAPETNFEGKLSSDIKTQ--- 297
             P ++   +V+T+ EM        +  +I I CAA++DY   T    K+     TQ   
Sbjct: 241 PTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIKKQ-ATQGDE 299

Query: 298 -VIKLKQTPKVLEELRK-KFPKKIIVGYKAEYGINLDELKEKAISRLEKYNLDVIIANDL 355
             IK+ + P ++  +   K  +  +VG+ AE     + ++E A  +  + NLD+I AND+
Sbjct: 300 LTIKMVKNPDIVAGVAALKDHRPYVVGFAAE----TNNVEEYARQKRIRKNLDLICANDV 355

Query: 356 SK------------HYFGDDLNEVLIIDKEKAL 376
           S+            H F  D ++VL +++++ L
Sbjct: 356 SQPTQGFNSDNNALHLFWQDGDKVLPLERKELL 388