Pairwise Alignments

Query, 1034 a.a., isoleucine--tRNA ligase from Methanococcus maripaludis S2

Subject, 948 a.a., valyl-tRNA synthetase from Pseudomonas simiae WCS417

 Score =  180 bits (457), Expect = 4e-49
 Identities = 196/876 (22%), Positives = 345/876 (39%), Gaps = 177/876 (20%)

Query: 20  WKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNKIIKDTVLRFKRIQGYNVLD 79
           W+ EN +    A    G  Y  +  PP  +G++H+G  +N  I D ++RF+R+QG N L 
Sbjct: 18  WESENYFAPQGA----GDSYTIMIPPPNVTGSLHMGHGFNNAIMDALIRFRRMQGRNTLW 73

Query: 80  KAGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCKEFALNHLGHMQGQFENLGV 139
           + G D  G+  ++ VE +     +   +  +G ++F+ K  E+     G++  Q   LG 
Sbjct: 74  QPGTDHAGIATQMLVERQLEATGQSRHD--LGREKFLEKIWEWKDQSGGNISRQIRRLGS 131

Query: 140 WLDFENAYMPIKRDYMEMGWWTLKKAHEKELLTKDLRSGYWCPRCETSLAEHEVRGEYKE 199
            +D+      +     E       + HE  L+ +  R   W  +  T++++ E       
Sbjct: 132 SVDWSRERFTMDDGLSEAVKEAFVRLHEDGLIYRGKRLVNWDTKLHTAISDLE------- 184

Query: 200 VLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEFDYAYVNVEFENGTAETWII 259
                      +E  DE   +W                        N+++          
Sbjct: 185 -----------VENHDEKGFLW------------------------NLKYP--------- 200

Query: 260 AEKLVNDVMKKAEKNND-ISKFSISKVVKGDSLIGLKYIHPLLEENE----KQQEFAKIE 314
               + D  K AE N+  I   +  + + GD+ +    ++P  E  +    K  E   + 
Sbjct: 201 ----LADGAKTAEGNDYLIVATTRPETMLGDAAVA---VNPTDERYQALIGKFVELPLVG 253

Query: 315 NVHTIVPGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPIDDN------------ 362
               I+  D+   E GTG V   P    +D+ +GK HN+P+    D N            
Sbjct: 254 RRIPIIADDYCDPEFGTGCVKITPAHDFNDYEVGKRHNLPLLNIFDKNAAVLPACQVFNL 313

Query: 363 -GKYTDSI-------WKGTFVKDMDESVIETLISKNLLVNSGKVKHTYPHCWRCKTPLLF 414
            G   +SI       + G    +  + ++    +  LLV+        P   R  T +  
Sbjct: 314 DGTLNESIDGKIPAEYAGLDRFEARKQIVAAFDAAGLLVSVDDHALKVPKGDRSGTVIEP 373

Query: 415 RATEQWFLSISKIKD---SIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPL 471
             T+QW++S   + +   + +E G+ + +VP   +  Y + +  + DW ISRQ +WG  +
Sbjct: 374 WLTDQWYVSTKPLAEPAIAAVEDGR-IQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRI 432

Query: 472 PIWICEECGNYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLD 531
           P W  +E G  +V    DE + RA          H    D           +++  DVLD
Sbjct: 433 PAWY-DESG--KVYVGRDEAEVRAK---------HNLGADI---------ALQQDNDVLD 471

Query: 532 VWYDSGLAPYASIG-------SKKLKKAQFITEGNDQVTKWFYSQHALSAVVFDD----- 579
            W+ SGL  ++++G        KK      +  G D +  W      L+  +  +     
Sbjct: 472 TWFSSGLWTFSTLGWPQQTEFLKKFHSTDVLVTGFDIIFFWVARMIMLTMHLVKNEDGTP 531

Query: 580 -TSYEKCMMHGFTLDETGEKMSKSLGNIVSPDDVTE------------------------ 614
              ++   +HG   D  G+KMSKS GN++ P D+ +                        
Sbjct: 532 QVPFKTVYVHGLVRDGQGQKMSKSKGNVLDPLDIIDGIDLETLVQKRTSGLMQPKLAKKI 591

Query: 615 -------------QYGADVLRFYLLSANKAWEDLRFSYSEMDETRSMLNTLWNSYAFSAN 661
                         YG D LRF   S      D++F    ++  R+  N +WN+  +   
Sbjct: 592 EKQTRDEFADGIASYGTDALRFTFCSLASTGRDIKFDMGRVEGYRNFCNKIWNAARY--- 648

Query: 662 YMVLD---DFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILN 718
             VLD   D   N E ++ +   D WI+S++     E    L++    +   AL +FI N
Sbjct: 649 --VLDKGEDCGQNGEAYE-LSLADRWIISQLQRTEAEVTRQLDQFRFDLAAQALYEFIWN 705

Query: 719 DFSRWYIKLIRDRTWMEKNDVQK-LSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTE 777
            +  WY++L +   W E   V++     +TL  V+   + +  P  P ++EEI+Q L   
Sbjct: 706 QYCDWYLELSKPVLWDENAPVERQRGTRRTLVRVLEVALRLAHPFMPFITEEIWQRLAPL 765

Query: 778 DMPE--SIFMNKLTIESEF-INETLEKDTEIIREIV 810
              E  +I +    + +E  I+E  E D E ++ ++
Sbjct: 766 AGIEGKTIMLQPWPVANEARIDEAAESDIEWLKTLM 801