Pairwise Alignments

Query, 492 a.a., 2-isopropylmalate synthase from Methanococcus maripaludis S2

Subject, 308 a.a., hydroxymethylglutaryl-CoA lyase from Agrobacterium fabrum C58

 Score = 70.5 bits (171), Expect = 8e-17
 Identities = 80/307 (26%), Positives = 136/307 (44%), Gaps = 29/307 (9%)

Query: 2   VNIFDTTLRDGEQTPGVSLSPSEKLELAIKLDELGVNIIEAGSAIT-SKGEREAMKLVTG 60
           V I +   RDG Q     +S + K+EL  +L   G+  +EAG+ ++  K  + A      
Sbjct: 7   VKIVEVGARDGLQNESAEVSTAIKIELIERLAAAGLPAVEAGAFVSPRKVPQMADSREVF 66

Query: 61  QNLNAEISSFVRALPVDI---DAALSCDVDSVHLVVPTSDIHMTYKLRKSREENLKDAMH 117
           Q L     +   AL  ++   +AA+   V  + + V  SD    + +  SR E+L+    
Sbjct: 67  QGLKRWPGTAYAALVPNMKGFEAAIEAGVTEIAVFVSASDGFSRHNIGCSRAESLERLRD 126

Query: 118 AVEYAKDHGL--------IVELSAEDATR-SDVEFLKELFLKGEELKADRICVCDTVGIL 168
             E A D  +        I     + A    DV  + E  +    L    I + DT+G+ 
Sbjct: 127 VAEAAADRNIRMRGYVSCIAGCPYDGAVAPDDVAAMAEALV---ALGCYEISLGDTIGVG 183

Query: 169 TPLKAIDLIKTMKNTI-KIPVSIHCHNDFGMATANTLSAISAGADQCHVTINGIG----- 222
           T  +  D+I+ +   I +  +++H H+ +G   AN L+++  G      ++ G+G     
Sbjct: 184 TAGQIRDVIERVATGIPRDQIAMHFHDTYGQGVANVLASLQEGIVVFDSSVAGLGGCPFA 243

Query: 223 -ERAGNASLEEVVMSLKSLYDIETGIDTEKLHKISRIVSKYMKIP--VPANKALVGDNAF 279
              +GN + E+VV  L+ L  IETGID   + K    +S+++  P    A KAL+   A 
Sbjct: 244 PGASGNVATEDVVYLLQGL-GIETGIDLMAVAKTGEWISRHLGRPNAARAGKALL---AA 299

Query: 280 AHEAGIH 286
             E  +H
Sbjct: 300 KQEGDLH 306