Pairwise Alignments

Query, 449 a.a., adenylosuccinate lyase from Methanococcus maripaludis S2

Subject, 438 a.a., Adenylosuccinate lyase (EC 4.3.2.2) @ SAICAR lyase (EC 4.3.2.2) from Sphingobium sp. HT1-2

 Score =  259 bits (663), Expect = 9e-74
 Identities = 158/440 (35%), Positives = 243/440 (55%), Gaps = 8/440 (1%)

Query: 9   RYGTPEMKKVWGEETKLQKMLEVEAALALAESELGMIPKEAAEEINRKKSTE-FVKLERV 67
           RY  P M  +W  E + +   E+EA       ELG++P  AA+ +    +T   + +  +
Sbjct: 4   RYSRPAMTALWEPEARFKIWFEIEAHATEKLGELGVVPPSAAKALWDWWATNPAIDVPAI 63

Query: 68  KEIEMATRHDVVSVVKAFAEQCEGTAGEYIHFGSTSNDIIDTAQSLQFKDAFEVLESKLK 127
             IE  T+HDV++ +   AEQ  G    ++H G TS+D++DT  ++Q   A ++L   L 
Sbjct: 64  DAIEAVTKHDVIAFLTWVAEQV-GDEARFMHQGMTSSDVLDTCLAVQLTRAADLLIEDLD 122

Query: 128 ILRGELLKKAEEHKNTVCIGRTHGQHAVPTTYGMKFALWATEIQRHIERLESSKKRLCVS 187
            L   + ++A EHK T  IGR+HG HA P T+G+K A    E  R   RL ++++ +   
Sbjct: 123 KLLDVIKRRAFEHKLTPTIGRSHGIHAEPVTFGLKMAEAYAEFSRCKTRLVAAREEVATC 182

Query: 188 MITGAVGTMAAIGENGILVHKRVGEILSLDPVLISNQVVQRDRHGEFMATLALIAQTLNK 247
            I+GAVGT A I      V + V E L L    +S QV+ RDRH  F ATL +IA ++ +
Sbjct: 183 AISGAVGTFANIDPR---VEEHVAEKLGLAIEPVSTQVIPRDRHAMFFATLGVIASSIER 239

Query: 248 IGVTVRSMQRSEIKELEEEFDASKQTGSSTMPHKRNPITFEQICGLSRIVKANALAEFDN 307
           + V VR +QR+E+ E EE F    Q GSS MPHKRNP+  E + GL+R+V++ AL   +N
Sbjct: 240 LAVEVRHLQRTEVLEAEEYFSPG-QKGSSAMPHKRNPVLTENLTGLARMVRSYALPAMEN 298

Query: 308 IPLWEERDLTNSSSERCLFPESCVLLDHIINLSIKGMRKLSVNLENVNKNLEMTKGLIMA 367
           + LW ERD+++SS ER + P++ + LD  +      + KL V  E + KNL+   GL+ +
Sbjct: 299 VALWHERDISHSSVERYIGPDATITLDFALGRLTGVIDKLLVYPERMMKNLDKMGGLVHS 358

Query: 368 ERVMMFLANSGMGRQTGHETVRKCAMKAHDEGRHLK--EVLLEEPEVMKYVSLDEIEKMF 425
           +RV++ L  +G+ R+  +  V++ AMK  +    L   E+L  + +V K +S  EIE  F
Sbjct: 359 QRVLLALTQAGVSREDSYRYVQRNAMKVWESDGQLSLLELLKADEDVAKALSAQEIEDKF 418

Query: 426 DYKTYIGLAPEIVENVLNEA 445
           +   +      I   V  EA
Sbjct: 419 NLDYHFKQVDTIFARVFGEA 438