Pairwise Alignments

Query, 330 a.a., ketol-acid reductoisomerase from Methanococcus maripaludis S2

Subject, 491 a.a., ketol-acid reductoisomerase, NAD(P)-binding from Escherichia coli BL21

 Score =  155 bits (392), Expect = 2e-42
 Identities = 103/288 (35%), Positives = 152/288 (52%), Gaps = 21/288 (7%)

Query: 14  LKEKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNG-----ASWNNAKADGHNVMTIEE 68
           L+ K + ++G G+QG  Q LNM+DSGL++   LRK       ASW  A  +G  V T EE
Sbjct: 35  LQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEE 94

Query: 69  AAEKADIIHILIPDELQAEVYESQIKPYLKEGKTLSFSHGFNIHYGFIVPPKGVNVVLVA 128
              +AD++  L PD+  ++V  + ++P +K+G  L +SHGFNI        K + VV+VA
Sbjct: 95  LIPQADLVINLTPDKQHSDVVRT-VQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVA 153

Query: 129 PKSPGKMVRRTYEEGFGVPGLICI--EIDATNNAFDIVSAMAKGIGLSRAGVIQTTFKEE 186
           PK PG  VR  Y+ GFGVP LI +  E D       I  A A   G  RAGV++++F  E
Sbjct: 154 PKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAE 213

Query: 187 TETDLFGEQAVLCGGVTELIKAG----FETLVEAGYAPEMAYFETCHELKLIVDLIYQKG 242
            ++DL GEQ +LCG    +++AG    F+ LVE G  P  A        + I + + Q G
Sbjct: 214 VKSDLMGEQTILCG----MLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGG 269

Query: 243 FKNMWNDVSNTAEYGGLTRRSRIVTADSKAAMKEILREIQDGRFTKEF 290
              M + +SN A+      R+  ++   K  M  + ++  D   + EF
Sbjct: 270 ITLMMDRLSNPAKL-----RAYALSEQLKEIMAPLFQKHMDDIISGEF 312



 Score = 59.7 bits (143), Expect = 1e-13
 Identities = 51/156 (32%), Positives = 74/156 (47%), Gaps = 22/156 (14%)

Query: 182 TFKEETETDLF----------GEQAVLCGGVT--ELIKAG----FETLVEAGYAPEMAYF 225
           T++EET    F          GEQ     GV    ++KAG    FET+V++G   E AY+
Sbjct: 329 TWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYY 388

Query: 226 ETCHELKLIVDLIYQKGFKNMWNDVSNTAEYGGLTRRSRIVTADSKAAMKEILREIQDGR 285
           E+ HEL LI + I +K    M   +S+TAEYG     + + +      +K  + E+Q G 
Sbjct: 389 ESLHELPLIANTIARKRLYEMNVVISDTAEYG-----NYLFSYACVPLLKPFMAELQPGD 443

Query: 286 FTKEFLLEKQVSYAHLKSMRRLEGDLQIEEVGAKLR 321
             K  + E  V    L+ +        IE+VG KLR
Sbjct: 444 LGKA-IPEGAVDNGQLRDVNEAIRSHAIEQVGKKLR 478