Pairwise Alignments

Query, 330 a.a., 3-isopropylmalate dehydrogenase from Methanococcus maripaludis S2

Subject, 363 a.a., D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) from Variovorax sp. SCN45

 Score =  199 bits (506), Expect = 9e-56
 Identities = 125/355 (35%), Positives = 198/355 (55%), Gaps = 30/355 (8%)

Query: 2   HKICVIEGDGIGKEVVPAAVEVLKATG------VEFEFNHALAGDEVFEKTGVALPEETI 55
           + I  I GDGIGKEV+PA   V++A        ++F F     G + +   G  +P + +
Sbjct: 4   YSIATIPGDGIGKEVIPAGRRVMEALAEASGGALQFSFEDFGWGGDWYRAHGEMMPADGL 63

Query: 56  AAAKAADAILFGAAGE-------TAADVIVKLRKILDTYANIRPVKSYNGIN-----CLK 103
              +  DAILFG+AG+       T   + +K+ +  D YAN+RP +   GI+     C  
Sbjct: 64  DTLRKKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRCAP 123

Query: 104 TGIDYIIVRENTEGLYKGIEAEIADG--VTVATRV--ITKDASERIFKHAFEMAKDRKKQ 159
             +D++IVREN+EG Y G+   +  G  +  AT V  +T+   ERI + AF++A+ R ++
Sbjct: 124 GQLDWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLARSRPRK 183

Query: 160 GTAGKVTCAHKANVLKITDGLFKKTFYEVSNDYKDIQTEDFYVDAMNMFIISRPETFDIV 219
                +T   K+N  +    ++ +   ++S ++ D+  +   VDA    +++RP + D +
Sbjct: 184 ----LLTVVTKSNAQRHAMVMWDEIALQISKEFPDVTWDKELVDACTARMVNRPASLDTI 239

Query: 220 VTSNLFGDILSDGAVGMVGGLGMAPSGNVGDKY---GLFEPIHGSAPDIAGKGLANPTAT 276
           V +NL  DILSD A  + G LG+AP+GN+  +     +FEPIHGSA DI GKGLANP  T
Sbjct: 240 VATNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGT 299

Query: 277 ILTAVMMLRYLKENEAAEKVEKALEEV-LSLGLTTPDLGGTLSTSEMGQEVAKRV 330
             + VM+L +L E EAA +V +A+E V  +  L T DLGG+ +T ++ + V   +
Sbjct: 300 FWSVVMLLEHLGEAEAARRVMQAVEHVTANPALHTRDLGGSATTEQVTRAVCAHI 354