Pairwise Alignments

Query, 834 a.a., HAD-IC family P-type ATPase from Methanococcus maripaludis S2

Subject, 785 a.a., Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) from Sphingobium sp. HT1-2

 Score =  148 bits (373), Expect = 1e-39
 Identities = 156/608 (25%), Positives = 266/608 (43%), Gaps = 107/608 (17%)

Query: 72  SIMVISVIFICAIEFFQEWRTDRTLQALKELSSPKST--VIRNGKMMTIDSTELIVNDLL 129
           +++ + V+    +E     RT   ++AL  L+ PK+   +  +G    I    + V D L
Sbjct: 240 AVITVLVLLGQMLELRARERTSGAIKALLNLA-PKTARRIGSDGNEEEISLDLVAVGDRL 298

Query: 130 ILKEGEKIAADGIIVENYGLGVNESTLTGESDVVWKKIDLKEDETLEHWKKNICYAGTSV 189
            ++ GEK+  DG+ VE+    ++ES +TGES  V K             K +    GT  
Sbjct: 299 RVRPGEKVPVDGV-VEDGRSSLDESMVTGESMPVTKA------------KADTVIGGTLN 345

Query: 190 TQGRAVVKVIHIGSETEYGKIGKDIFSVESMPTPLEKQTEKLVKYSAIAAFFMLLLIVL- 248
             G  V+    +G +T   +I + +   +    P+++  ++      ++ +F+ ++I + 
Sbjct: 346 QTGALVIVADKVGRDTMLARIVQMVAEAQRSRAPIQRMADQ------VSGWFVPVVIAVA 399

Query: 249 -VNFYYRG------SVTDSILSGVTVAMAIIPEEFPVILTVFLAMGAWRLANKNSLIRRI 301
            V F   G           +++ V V +   P    +   + + +G  R A    LI+  
Sbjct: 400 AVAFIAWGIWGPEPRFAYGLVAAVAVLIIACPCALGLATPMSIMVGVGRGAGLGVLIKNA 459

Query: 302 PAVETLGSISLLCVDKTGTLTKNQMEVKETYFDSKFNETELMTYACLASETEAYDPMEKA 361
            A+E +  +  L VDKTGTLT+ +  V +      F+E EL+  A  + E  +  P+  A
Sbjct: 460 EALEHMEKVDTLVVDKTGTLTEGRPAVTQVVPAPGFDEAELLRLAA-SVERASEHPLALA 518

Query: 362 IMIYSKSIRINIDELCTGCLLHEYPFSSETRMMGNVWNKDNKKFIALKGSFENIINLCDL 421
           I+  +K   I   ++          F S T   G +   + ++ +     F         
Sbjct: 519 IVEAAKDRGIVTSDVID--------FDSPTGR-GALGTVEGRRIVLGNAQF--------- 560

Query: 422 KESEKVNLEKKSIEMAKKGYRVIAVAKKMDVVTINQHLDEYTFEFVGLIG-------LMD 474
                         +A +G    A+A + D +      D  T  F+G+ G       + D
Sbjct: 561 --------------LADEGVATDALASQADAL----RRDGATAIFIGVDGTVGGAFAIAD 602

Query: 475 PPREGVSKAMKICNNAGIRVVMLTGDNGTTAKSIAKTIGLKNSENVLTGNEIDSMGDEEL 534
           P +    +A+      GIRVVMLTGDN TTA+++A+ +G+   E                
Sbjct: 603 PVKATTPEALAALKAEGIRVVMLTGDNRTTAEAVARRLGIDEVE---------------- 646

Query: 535 LEKINVTNIFSRVIPKHKLRIIKAFKKLGEIVAMTGDGVNDAPALKYADIGVAMGKRGTE 594
                     + V+P  K  ++  FK+ G +VAM GDGVNDAPAL  AD+G+AMG  GT+
Sbjct: 647 ----------AEVLPDQKSAVVARFKREGRVVAMAGDGVNDAPALAAADVGIAMGS-GTD 695

Query: 595 VAKEASDMILLDDNFETIVETIHDGRRIYDNIKKAIGYVFVIH---IPVFLTALFAPLLK 651
           VA E++ + LL  +   IV      +    NI++ + + F+ +   +PV   AL+ PL  
Sbjct: 696 VAIESAGVTLLKGDLTGIVRARRLSQATMSNIRQNLVFAFIYNVAGVPVAAGALY-PL-- 752

Query: 652 LPLLLLPI 659
             +LL PI
Sbjct: 753 FGILLSPI 760