Pairwise Alignments

Query, 663 a.a., methionine--tRNA ligase from Methanococcus maripaludis S2

Subject, 677 a.a., methionine--tRNA ligase from Escherichia coli ECRC62

 Score =  340 bits (873), Expect = 1e-97
 Identities = 214/677 (31%), Positives = 347/677 (51%), Gaps = 27/677 (3%)

Query: 4   LVTTALAYTNGPLHLGHARSTYIPADIFTRYLKLKGEEVIHVGGTDNHGVPITLTAEKEG 63
           LVT AL Y NG +HLGH    +I AD++ RY +++G EV  +   D HG PI L A++ G
Sbjct: 9   LVTCALPYANGSIHLGHMLE-HIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLG 67

Query: 64  VKPIDIVDRYHNAIKADLDSLNICFDNFGRTHSDIHIETAQEFYSKLKENGYIYEKEIEQ 123
           + P  ++       + D    NI +DN+  THS+ + + ++  YS+LKENG+I  + I Q
Sbjct: 68  ITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQ 127

Query: 124 FYCEKCDMYLADRYVEGICPFCEG-EARGDHCEVCGRHLEPTELVNPYCIHCNSKPEIKR 182
            Y  +  M+L DR+V+G CP C+  +  GD+CEVCG    PTEL+ P  +   + P ++ 
Sbjct: 128 LYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRD 187

Query: 183 TTHYFFKLSAMQDSLKEYIENSPEMPEHVKNMALRWIEE-LHDWDVSRNIKW-GVPIPGC 240
           + H+FF L +  + L+ +   S  + E V N    W E  L  WD+SR+  + G  IP  
Sbjct: 188 SEHFFFDLPSFSEMLQAW-TRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNA 246

Query: 241 DDQVMYVWIEAPIGYVSFTKQLGD------IWKSYWLENTDDSKISHFIGKDITVHHAVF 294
             +  YVW++APIGY+   K L D       +  YW +++  +++ HFIGKDI   H++F
Sbjct: 247 PGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDS-TAELYHFIGKDIVYFHSLF 305

Query: 295 WPGILKGIGGYKMPNAVVSGGYLTLENKKMSTSKNWVVWVKDFVENFSSDYLRYFFMINA 354
           WP +L+G   ++ P  +   GY+T+   KMS S+   +    ++ +F +D LRY++    
Sbjct: 306 WPAMLEG-SNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKL 364

Query: 355 PLN-RDTDFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPIVDLNQLKDEDKKLI 413
                D D + +DF +R+N ++++ + N   R   F  ++F      +L      D +L 
Sbjct: 365 SSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASEL-----ADPQLY 419

Query: 414 SKCDDTEKLVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAI-KNEERLKEVMYTCS 472
               D  +++        F  A+ EI+ LA   N Y    APW + K E R  ++   CS
Sbjct: 420 KTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICS 479

Query: 473 V---VLKYIIYLLSSFMPEKTALLLEYMNEELDLKVRGNPLKKPKV-IFTKVSDEDISRM 528
           +   + + ++  L   +P+ T     ++N EL       PL   KV  F  + +    + 
Sbjct: 480 MGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQ 539

Query: 529 KENLMKATK-KAETKSDEKSKKVKSGEKMDIIDIDYFGNIDLRVGQILEVEEVPRSKKLY 587
            E L++A+K + +  +   +  +      + I  D F  +DLRV  I   E V  S KL 
Sbjct: 540 VEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLL 599

Query: 588 KIIADLGDEKRQIVSGLIGAY-DAEELVGKKVIIICNLKPAKLCGVESQGMLLAA-EDDS 645
           ++  DLG EKR + SG+  AY D + L+G+  I++ NL P K+    S+GM++AA     
Sbjct: 600 RLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGK 659

Query: 646 IVSLLSLDRDLPVGSKI 662
            + LLS D     G ++
Sbjct: 660 DIFLLSPDAGAKPGHQV 676