Pairwise Alignments

Query, 507 a.a., bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase from Methanococcus maripaludis S2

Subject, 510 a.a., bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase from Escherichia coli ECRC62

 Score =  112 bits (279), Expect = 4e-29
 Identities = 130/489 (26%), Positives = 207/489 (42%), Gaps = 79/489 (16%)

Query: 41  ENSEQYGISKETLMENAGRAVYEEIVNLNVDFSKTYLFCGTGNNGGDGFVIARHLANNFA 100
           E ++  G++   LM  AG A ++   +   D     + CG GNNGGDG+V+AR LA    
Sbjct: 24  EAADALGLTLYELMLRAGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVAR-LATAVG 82

Query: 101 TFVVLIGNERKIKTSETQRNFNTVKNMEFFGNLDYANILDDERAVELLKTIEKELENKQN 160
             V L+  E   K    +        +   G +  +NI+  E                  
Sbjct: 83  IEVTLLAQESD-KPLPEEAALAREAWLNAGGEIHASNIVWPESVD--------------- 126

Query: 161 DHILIIDAMLGTGITGILKNPYSTIVDYLNVLKSKYSKKLKMVSVDIQTGNL-------- 212
              LI+DA+LGTG+    +   S ++D+ N      S    + +VDI +G L        
Sbjct: 127 ---LIVDALLGTGLQQAPRESISQLIDHAN------SHPAPIAAVDIPSGLLAETGATPG 177

Query: 213 ---NAD-------LEVILHKRKFENKNKNFVVKDIGIPKY-------IENMVGKGDFYLL 255
              NAD       L+  L   K  +         +G+  +       I+    +   + L
Sbjct: 178 AVINADHTITFIALKPGLLTGKARDVTGQLHFDSLGLDSWLAGQETKIQRFSAEQLSHWL 237

Query: 256 NERKQNSHKGQNGNVLVIGGSKEYHGAPVFSALAASKF-ADIVTVASVS-NVMNTVSNYP 313
             R+  SHKG +G +++IGG     GA   +  AA +  A +V V + S N+   ++  P
Sbjct: 238 KPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEAALRAGAGLVRVLTRSENIAPLLTARP 297

Query: 314 ELMPYELTGDYIVQNHVDELLELSKNYDCVVLGSGISVNSDTKEFVNSYLNETNGKVVID 373
           ELM +ELT        +D L E  +  D VV+G G+      K+ +    N     ++ D
Sbjct: 298 ELMVHELT--------MDSLTESLEWADVVVIGPGLGQQEWGKKALQKVENFRK-PMLWD 348

Query: 374 ADAIKLIDYSNFKFKNNFIFTPHKKEFEYIENY----IESSG----------FKSTVVLK 419
           ADA+ L+  +  K ++N + TPH  E   +       IES            +    VLK
Sbjct: 349 ADALNLLAINPDK-RHNRVITPHPGEAARLLGCSVAEIESDRLHCAKRLVQRYGGVAVLK 407

Query: 420 GSLDIIF-NSNNIKMNITGNQGMTVGGTGDILCGIIGAIYACN-DAFPSACCGTYINGYC 477
           G+  ++  + + + +   GN GM  GG GD+L GIIGA+       + +AC G   +G  
Sbjct: 408 GAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVAHGAA 467

Query: 478 GDLLEKEYG 486
            D+L   +G
Sbjct: 468 ADVLAARFG 476