Pairwise Alignments

Query, 460 a.a., MATE family efflux transporter from Methanococcus maripaludis S2

Subject, 457 a.a., multidrug efflux MATE transporter MdtK from Escherichia coli ECRC62

 Score = 85.1 bits (209), Expect = 4e-21
 Identities = 86/433 (19%), Positives = 179/433 (41%), Gaps = 32/433 (7%)

Query: 16  KAIVKISLPMVIAMSFQSLYNVIDAIWVAGLGSDALAAIGLFFPFMFAIMAISNGVGIGG 75
           + ++ +++P+++A   Q+    +D +   G  +  +AA+ +        +   +G+ +  
Sbjct: 9   RLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLAL 68

Query: 76  SSAISRRIGQNNKDAADNIAVHSIVLGIIIGILLIGVIPFLGAIF-SLIGASGITVTMAV 134
           +  I++  G   ++   +       L   + +L++ V+   G I  S+          AV
Sbjct: 69  TPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAV 128

Query: 135 EYSTILFGGAVVLLFTNIANAILRGEGDTKRAMYAIILGSVLNIVLDPIFIY----VLNM 190
            Y   L  GA   LF  +A     G   TK  M    +G ++NI ++ IFIY    +  +
Sbjct: 129 GYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPEL 188

Query: 191 GVAGAAWATLLSLVITGILFVYW-LFIKKDTFLK-------ISFEK--FKLDINIIKEIF 240
           G  G   AT           VYW +F+   +++K       I  EK   K D  ++K + 
Sbjct: 189 GGVGCGVATAA---------VYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLI 239

Query: 241 SIGLPASISHLTMAFSMFLLTAIVAKAGGNDGIAVFSTGWRIVSMGTIPLVGLATGVTVV 300
            +GLP +++ L    ++F + A++    G   +A         S+  +  + LA  VT+ 
Sbjct: 240 QLGLPIALA-LFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIR 298

Query: 301 TGAAYGSANPEKLEISYKYALKMGILVETIIAALILIFENQITYLFTYSENSVHILEGLL 360
            G   G  +    + + +  L +G+ + T+ A   +    QI  L+  +   V +   L+
Sbjct: 299 VGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLM 358

Query: 361 VFLKYMFLFYPTLPLGMLTAAMFQGVSKGNNSLFISLLRTIILQIPMAYTFG----IIFN 416
           +      ++  +  + ++ + + +G     +  +I+     +L +P  Y       ++  
Sbjct: 359 LLAA---VYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEP 415

Query: 417 QGLTGVWFGMILG 429
            G  G W G I+G
Sbjct: 416 MGPAGFWIGFIIG 428