Pairwise Alignments

Query, 460 a.a., MATE family efflux transporter from Methanococcus maripaludis S2

Subject, 547 a.a., putative multdrug exporter, MATE family from Escherichia coli BL21

 Score =  130 bits (328), Expect = 8e-35
 Identities = 110/437 (25%), Positives = 198/437 (45%), Gaps = 23/437 (5%)

Query: 16  KAIVKISLPMVIAMSFQSLYNVIDAIWVAGLGSDALAAIGLFFPFMFAIMAISNGVGIGG 75
           + I  +++P+ +  +   L  V+    V+ LG DA+A +GL   F   IMA    + +G 
Sbjct: 92  REITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGT 151

Query: 76  SSAISRRIGQNNKDAADNIAVHSIVLGIIIGILLIGVIPFLG-AIFSLIGASGITVTMA- 133
           +  ++  +G+ ++  A      S+V+  +  +LL  +I   G  I   +     T   A 
Sbjct: 152 TVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKAL 211

Query: 134 ----VEYSTILFGGAVVLLFTNIANAILRGEGDTKRAMYAIILGS--VLNIVLDPIFIYV 187
               +E + + +  A + L   I +  LRG G+TK  +  +I GS  +LNI++  I IY 
Sbjct: 212 ALTYLELTVLSYPAAAITL---IGSGALRGAGNTKIPL--LINGSLNILNIIISGILIYG 266

Query: 188 L----NMGVAGAAWATLLSLVITGILFVYWLFIKKDTFLKISFEKF--KLDINIIKEIFS 241
           L     +G  GA     +S  I  +  ++ L I  +  L+IS + +   L+ +II E+  
Sbjct: 267 LFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMG 326

Query: 242 IGLPASISHLTMAFSMFLLTAIVAKAGGNDGIAVFSTGWRIVSMGTIPLVGLATGVTVVT 301
           IG+PAS+  +    S  LLT +     G   IA     + I ++  +P   L +  T++T
Sbjct: 327 IGIPASVESVLFT-SGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIIT 385

Query: 302 GAAYGSANPEKLEISYKYALKMGILVETIIAALILIFENQITYLFTYSENSVHILEGLLV 361
           G   G     + EI  ++   +  L  T IA L   F   +   +T      H++  +L+
Sbjct: 386 GRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVV-ILI 444

Query: 362 FLKYMFLFYPTLPLGMLTAAMFQGVSKGNNSLFISLLRTIILQIPMAYTFGIIFNQGLTG 421
           +L  +F+  P      +  A F+G      ++++S+L     ++ + Y  GI+   G+ G
Sbjct: 445 WLNALFM--PIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVG 502

Query: 422 VWFGMILGHVIAVSIAY 438
           VW GM     +   + Y
Sbjct: 503 VWMGMFADWAVRAVLFY 519