Pairwise Alignments

Query, 714 a.a., fused enoyl-CoA hydratase and epimerase and isomerase/3-hydroxyacyl-CoA dehydrogenase (NCBI) from Escherichia coli BW25113

Subject, 716 a.a., Enoyl-CoA hydratase (EC 4.2.1.17); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) (from data) from Shewanella sp. ANA-3

 Score =  403 bits (1036), Expect = e-116
 Identities = 261/723 (36%), Positives = 382/723 (52%), Gaps = 37/723 (5%)

Query: 8   TLNVRL--DNIAVITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNF 65
           T+ V L  DNIA +  + PG  +N    E  + + A +  +++   ++ +V  S K D F
Sbjct: 7   TIQVELLEDNIAKLCFNAPGS-VNKFDRETLASLDAALDSIKQQSNIQALVLTSGK-DTF 64

Query: 66  IAGADINMIGNCKTAQEAEALA--RQGQQLMAEIHALPIQVIAAIHGACLGGGLELALAC 123
           I GADI          +A  L+   Q   +  ++  LP    +AI G  LGGG E  LA 
Sbjct: 65  IVGADITEFLGLFAQDDAVLLSWIEQANAVFNKLEDLPFPTASAIKGFALGGGCETILAT 124

Query: 124 HGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQALKLG 183
             R+   D    +GLPE +LG++PG GGT RLPR+IG   ALE I TGK  R + ALK+G
Sbjct: 125 DFRIA--DTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGKDQRPEDALKVG 182

Query: 184 LVDDVVPHSILLEAAVELAK-------------KERPSSRPLPVRERILAGPLGRALLFK 230
            VD VV    L  AA+++ K             + + S   LP  E +++    + ++F 
Sbjct: 183 AVDAVVAPEALEAAAIQMLKDAVAEKLDWQARRQRKMSPLTLPKLEAMMSFTTAKGMVFA 242

Query: 231 MVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFF 290
           + GK        +YPA    + VVE    +G S     E +AF +LA T  ++AL  IF 
Sbjct: 243 VAGK--------HYPAPMAAVSVVEQAATKGRSDALQIEHQAFIKLAKTDVAKALIGIFL 294

Query: 291 ASTDVK-KDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGIPVRIKDINPQGINHAL 349
               VK K   +      + S  +LG G+MGGGIAY +A K G P+ +KDI    ++  L
Sbjct: 295 NDQLVKGKAKKAGKLAKDVKSAAVLGAGIMGGGIAYQSASK-GTPIVMKDIAQPALDLGL 353

Query: 350 KYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAE 409
             +   L  +V R      +  K L  I+   DY    H D+++EAV E+ ++K Q++AE
Sbjct: 354 GEAAKLLSAQVARGRSTPEKMAKVLNNITPALDYAPVKHADVVVEAVVEHPKVKAQVLAE 413

Query: 410 VEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQT 469
           VEQ  +   I ASNTS++ I  +A    +PE+  G+HFF+PV KMPLVE+I    +S +T
Sbjct: 414 VEQYVSEDAIIASNTSTISINLLAKSMKKPERFCGMHFFNPVHKMPLVEVIRGEHSSEET 473

Query: 470 IATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIRMLTQGERVEHIDAALVK-FGF 528
           IA+ V  A K GKTPIVV D  GF+VNR+L PY      +L +G     ID  + K FG+
Sbjct: 474 IASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGW 533

Query: 529 PVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPAN-VVSSILNDDRKGRKNGRGFYLYG 587
           P+GP  LLD VG+DTG     V+   + +R     N  +  +  + R G+KNG+GFY Y 
Sbjct: 534 PMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGNDAIDVMFENKRLGQKNGKGFYAYS 593

Query: 588 QKGR-KSKKQVDPAIYPLIGTQ--GQGRISAPQVAERCVMLMLNEAVRCVDEQVIRSVRD 644
              R K KK VDP  Y L+      Q    A ++  R ++ M+ E VRC++E ++ S  +
Sbjct: 594 VDSRGKPKKDVDPTSYELLKAAFGEQKAFDADEIIARTMIPMIIETVRCLEEGIVASPAE 653

Query: 645 GDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMGARGES 704
            D+G V+G+GFPPF GG FRY+D++G    VA+  + A   G  +   + +  + A   S
Sbjct: 654 ADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYA-HLGGLYQVTDAMRALAANNGS 712

Query: 705 FWK 707
           +++
Sbjct: 713 YYQ 715