Pairwise Alignments
Query, 1049 a.a., cytochrome C peroxidase from Cupriavidus basilensis FW507-4G11
Subject, 1443 a.a., heavy metal efflux pump (cobalt-zinc-cadmium) from Echinicola vietnamensis KMM 6221, DSM 17526
Score = 660 bits (1703), Expect = 0.0
Identities = 385/1041 (36%), Positives = 605/1041 (58%), Gaps = 32/1041 (3%)
Query: 1 MLAGLIEFSLRQRALVLIAACVLAVAGAWAYLKLPIDAFPDISPTQVKVILKIPGMTPEE 60
ML LI++SL+ + ++L+ + G +A +P+ A PDI+ QV+VI + E+
Sbjct: 1 MLQKLIQYSLQHKLVILLFTLGILGFGLYALTHIPLGAVPDITNNQVQVITTSKNLATED 60
Query: 61 VEQRVSTPIEQELLGIPHKTIVRSVSKYGISDVTVDFEEGVDSYWARQQVSERLAGLLRD 120
VE+ ++ P+E E+ +P+ +RSVSK+G+S VTV F++ +Y RQ ++E+L L +
Sbjct: 61 VEKFLTYPVELEMANLPNVKEIRSVSKFGLSIVTVVFDDKAGTYLPRQLIAEKLK-LAEE 119
Query: 121 LPPNAIGG--LAPITTPLGEMFMFTVE-----GDAFSLAERRRVLDWVLRPALRTVPGVA 173
P G + PI+T LGE++ + ++ +S A+ R + DW++R L +PGV
Sbjct: 120 RIPEGFGSPFMGPISTGLGEIYQYIIDVAPEYKGEYSTADLRTIQDWIIRRQLSGIPGVV 179
Query: 174 DVNALGGEVRSYEVIPDPARLRARAVTVEQLRQALDANNRNDGAGRVEQGDENWVVRVEG 233
++N GG ++ YEV DP +LRA + + +L L NN G G +E+ +E + VR EG
Sbjct: 180 EINTWGGYLKQYEVAVDPEKLRAMNIPLRKLYTVLRDNNSIAGGGYIEKTEETYFVRGEG 239
Query: 234 GVRGVEDLRQVAVAAPGGRNGMPLVTVGDVATVRLGVATRNGAVSKDGRGEAVQGLVLAL 293
V +ED+ + V RNG+P V V DVA VR G ATR GA++ +G GE V G V+ L
Sbjct: 240 LVESLEDIGNIVVE---NRNGVP-VYVSDVAEVRFGHATRFGAITGNGEGEKVLGQVMML 295
Query: 294 RGADARQLVADVQARLDALAPQLPKGMSTHVFYNRGELVTRAANTVVRALIEASLLVVVT 353
+GAD++ ++ V R++A+ P LP G+ + F R EL+ + T+ LI L+V+
Sbjct: 296 KGADSQAVINAVAERVEAIKPSLPPGIIINPFLERSELIGKTTFTIAENLILGCLIVIFV 355
Query: 354 LYLFLGGLRAALVVAATLPLSMLATFMLMRYVGLTANLMSLGGLAIALGMLVDAAVVVVE 413
+ L LG LR+ALVVA+ +PL +L LM G+ ANLMSLG AI G+++D AV++VE
Sbjct: 356 VVLLLGNLRSALVVASVIPLCLLFALSLMYLTGVDANLMSLG--AIDFGIIIDGAVIIVE 413
Query: 414 NIESALAKAHERKSDPSLRGAVIRHAVASVAV--------PMLAGVSIIAIVFLPLLSLQ 465
I + + S L+G + A+ + + G II IVF+P+LSL
Sbjct: 414 FIAYQITA--QNASLIGLKGKERQVAIDRITFLGASKMMHSAVFGQLIIIIVFIPILSLV 471
Query: 466 GLEGKLFGPVALTIVLALASSVAIAFTVVPALASLLLR----THADESPYLMRKVARGFA 521
+EGK+F P+A+ AL ++ + FT VP +++L ++ + A+ S L+ V R +
Sbjct: 472 NVEGKMFRPMAMVFCYALVGAMVLCFTYVPVMSALFIKPSKKSGANISVKLIAAVYRIYQ 531
Query: 522 RLQDWSARHPRAVFASAGVALAVAVALYLSVGKTFMPTMDEGDMIVQLQKAPSVSLATSV 581
WS RH + V + AG L +A L+ +G F+PT+DEGD ++Q SL ++
Sbjct: 532 PAIYWSLRHKKMVLSMAGGLLLLAGLLFFRMGGEFVPTLDEGDFVIQPVLKTGTSLQKTI 591
Query: 582 GLDLRVQQALLAEVPEIRSIVARSGSDDLGLDPMGLNETDTFLALRPKDQW--RGSKEDI 639
++++ LL PE+ +V R G+ ++ DPM + E+D + L PK++W +K+ +
Sbjct: 592 ETTTKMEKILLG-FPEVDQVVTRIGAAEVPTDPMSMEESDVIIKLHPKEEWVTAETKDGL 650
Query: 640 ASAIRRVMERFPGVVYGFTQPIEMRVSEMLTGTRGDVAIKVFGSDLGAIDTAAQAIAARV 699
A A + + PG+ + FTQPIEMR +E++TG R D+AIK+FG DL + A + +
Sbjct: 651 ADAFKTALSILPGIDFEFTQPIEMRFNELITGVRADLAIKIFGEDLDLLYQKALEVETAI 710
Query: 700 RKIPGAAEVIAPSNEGVQYLTLALDRAAVGRAGLSGDALQALLRAQVEGERIGIVPEGTV 759
+++ GA+++I G+ +++ DR + + GL+ AL L+ G G V EG
Sbjct: 711 QQVEGASDIIVEKTAGLPQMSVNYDRRKIAKYGLNVSALNELISMGFAGLPAGTVFEGEK 770
Query: 760 RTPLILRGSDSLRQTPETFTSLQVTAPDGTSWPLTSLAQVRRVEGPVRINHEDGGRFAVI 819
+ L+LR R++ E S V P+G S PL+ A + GP +I+ +D R V+
Sbjct: 771 QFDLVLRFDPEHRKSLEDIQSASVQLPNGHSLPLSEFASIGFTTGPAKISRDDTKRRIVV 830
Query: 820 QVSVEGRDLTGFVQEAQTSVAGLAGLPKGLRVAWGGQFENQQRAAARLALVVPLALGAIF 879
V+V RDL V++ + + LP G V +GGQFEN + A RL + VP+AL IF
Sbjct: 831 GVNVRNRDLESVVEDVRKIIEEKIELPTGYSVTYGGQFENLRTARERLMVAVPIALLLIF 890
Query: 880 LLLMLTFRSIRQAALVIANIPFALVGGIAALRVAGEYLSVPASVGFIALLGIAVLNGVVL 939
++L F SI++A ++ + IP A VGG+ L G S+ A VGFIAL GIAVLNG+VL
Sbjct: 891 VMLYFAFGSIKEAFIIYSAIPLAAVGGVFLLYFRGLPFSISAGVGFIALFGIAVLNGIVL 950
Query: 940 VSHFNTLLEEGLP-MAEAVRTGVRDRLRPVLMTACITALGMIPLLLASGPGSEIQRPLAI 998
+ F L ++G+ + +AV G + RLRPVL+TA ALG +P+ ++ G+E+QRPLA
Sbjct: 951 IEEFKELRDQGIKNVHKAVLIGTKKRLRPVLLTASAAALGFLPMAVSHSAGAEVQRPLAT 1010
Query: 999 VVSGGLVSSTALTLLLLPLLF 1019
VV GGLV++T LTLL++P+L+
Sbjct: 1011 VVVGGLVTATLLTLLVVPVLY 1031
Score = 75.9 bits (185), Expect = 2e-17
Identities = 111/523 (21%), Positives = 217/523 (41%), Gaps = 49/523 (9%)
Query: 6 IEFSLRQRALVLIAACVLAVAGAWAYLKLPIDAFPDISPTQ--VKVILKIPGMTPEEVEQ 63
I +SLR + +VL A L + + ++ + P + ++ +LK + +E
Sbjct: 534 IYWSLRHKKMVLSMAGGLLLLAGLLFFRMGGEFVPTLDEGDFVIQPVLKTGTSLQKTIE- 592
Query: 64 RVSTPIEQELLGIPHKTIVRSVSKYGISDVTVD---FEEG-------VDSYWARQQVSER 113
+T +E+ LLG P + + V++ G ++V D EE W + +
Sbjct: 593 -TTTKMEKILLGFPE--VDQVVTRIGAAEVPTDPMSMEESDVIIKLHPKEEWVTAETKDG 649
Query: 114 LAGLLRDLPPNAIGGLAPITTPLGEMFMFTVEGDAFSLAER----------RRVLDWVLR 163
LA + G T P+ F + G LA + ++ L+ +
Sbjct: 650 LADAFKTALSILPGIDFEFTQPIEMRFNELITGVRADLAIKIFGEDLDLLYQKALE--VE 707
Query: 164 PALRTVPGVAD--VNALGGEVRSYEVIPDPARLRARAVTVEQLRQALDANNRNDGAGRVE 221
A++ V G +D V G + V D ++ + V L + + AG V
Sbjct: 708 TAIQQVEGASDIIVEKTAG-LPQMSVNYDRRKIAKYGLNVSALNELISMGFAGLPAGTVF 766
Query: 222 QGDENW--VVRVEGGVR-GVEDLRQVAVAAPGGRNGMPLVTVGDVATVRLGVATRNGAVS 278
+G++ + V+R + R +ED++ +V P G + +PL + G T +S
Sbjct: 767 EGEKQFDLVLRFDPEHRKSLEDIQSASVQLPNGHS-LPLSEFASI-----GFTTGPAKIS 820
Query: 279 KDGRGEAVQGLVLALRGADARQLVADVQARLDALAPQLPKGMSTHVFYNRGELVTRAANT 338
+D + + + +R D +V DV+ ++ +LP G S + + E + A
Sbjct: 821 RDDTKRRIV-VGVNVRNRDLESVVEDVRKIIEEKI-ELPTGYSV-TYGGQFENLRTARER 877
Query: 339 VVRALIEASLLVVVTLYLFLGGLRAALVVAATLPLSMLATFMLMRYVGLTANLMSLGGLA 398
++ A+ A LL+ V LY G ++ A ++ + +PL+ + L+ + GL ++ + G
Sbjct: 878 LMVAVPIALLLIFVMLYFAFGSIKEAFIIYSAIPLAAVGGVFLLYFRGLPFSISAGVGFI 937
Query: 399 IALGMLVDAAVVVVENIESALAKAHERKSDPSLRGAVIRHAVASVAVPMLAGVSIIAIVF 458
G+ V +V++E + + + L G R P+L S A+ F
Sbjct: 938 ALFGIAVLNGIVLIEEFKELRDQGIKNVHKAVLIGTKKRLR------PVLLTASAAALGF 991
Query: 459 LPLLSLQGLEGKLFGPVALTIVLALASSVAIAFTVVPALASLL 501
LP+ ++ P+A +V L ++ + VVP L +++
Sbjct: 992 LPMAVSHSAGAEVQRPLATVVVGGLVTATLLTLLVVPVLYTIM 1034
Score = 29.6 bits (65), Expect = 0.002
Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 19/166 (11%)
Query: 873 LALGAIFLL--LMLTFRSIRQAALVIANIPFALVGGIAALRVAGEYLSVPASVGFIALLG 930
L LG + ++ ++L ++R A +V + IP L+ ++ + + G ++ S+G I G
Sbjct: 345 LILGCLIVIFVVVLLLGNLRSALVVASVIPLCLLFALSLMYLTGVDANL-MSLGAIDF-G 402
Query: 931 IAVLNGVVLVSHF--------NTLL------EEGLPMAEAVRTGVRDRLRPVLMTACITA 976
I +++G V++ F N L E + + G + + I
Sbjct: 403 I-IIDGAVIIVEFIAYQITAQNASLIGLKGKERQVAIDRITFLGASKMMHSAVFGQLIII 461
Query: 977 LGMIPLLLASGPGSEIQRPLAIVVSGGLVSSTALTLLLLPLLFERF 1022
+ IP+L ++ RP+A+V LV + L +P++ F
Sbjct: 462 IVFIPILSLVNVEGKMFRPMAMVFCYALVGAMVLCFTYVPVMSALF 507