Pairwise Alignments

Query, 901 a.a., aconitate hydratase from Cupriavidus basilensis FW507-4G11

Subject, 891 a.a., aconitate hydratase 1; aconitase A from Escherichia coli BL21

 Score =  918 bits (2373), Expect = 0.0
 Identities = 484/904 (53%), Positives = 623/904 (68%), Gaps = 19/904 (2%)

Query: 1   MPHNLNKTLKEFKIGPSSKGQFYSLPQLGKALGVAVERLPVSIRVVLESVLRNCDGKKVT 60
           M   L +  K+          +YSLP   K+LG  + RLP S++V+LE++LR  DG  VT
Sbjct: 1   MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLG-DITRLPKSLKVLLENLLRWQDGNSVT 59

Query: 61  EEHVRQLAHWKPVAERVDEIPFVVARVVLQDFTGVPLLADLAAMRNVAEKMGKNPKKIEP 120
           EE +  LA W   A    EI +  ARV++QDFTGVP + DLAAMR   +++G +  K+ P
Sbjct: 60  EEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAAMREAVKRLGGDTAKVNP 119

Query: 121 LVPVDLVVDHSVQIDHFREKNALDLNMKLEFQRNNERYQFMKWGMQAFDTFGVVQPGFGI 180
           L PVDLV+DHSV +D F +  A + N++LE +RN+ERY F+KWG QAF  F VV PG GI
Sbjct: 120 LSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFLKWGKQAFSRFSVVPPGTGI 179

Query: 181 VHQVNLEYLARGVHKK--DG--VYYPDTLVGTDSHTTMINGIGVVGWGVGGIEAEAGMLG 236
            HQVNLEYL + V  +  DG  + YPDTLVGTDSHTTMING+GV+GWGVGGIEAEA MLG
Sbjct: 180 CHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLG 239

Query: 237 QPVYFLTPDVVGVELKGRLREGVTATDLVLTITEMLRREKVVGKFVEFFGEGTASLALPD 296
           QPV  L PDVVG +L G+LREG+TATDLVLT+T+MLR+  VVGKFVEF+G+G  SL L D
Sbjct: 240 QPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLAD 299

Query: 297 RATIGNMAPEYGATMGFFPVDEKTIDYFKGTGRTEEEIAAFEGYFRAQKMFGVPKAGEID 356
           RATI NM+PEYGAT GFFP+D  T+DY + +GR+E+++   E Y +AQ M+  P   E  
Sbjct: 300 RATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSEDQVELVEKYAKAQGMWRNP-GDEPI 358

Query: 357 YTNVVTLDLGTVAPSLAGPKRPQDRIEIGNVKSTFASLFAKPTAENGFNKDIAELDKTYT 416
           +T+ + LD+  V  SLAGPKRPQDR+ + +V   FA+  +     N  +KD   +D    
Sbjct: 359 FTSTLELDMNDVEASLAGPKRPQDRVALPDVPKAFAA--SNELEVNATHKDRQPVDYVMN 416

Query: 417 TADGVNVKSGDVLIAAITSCTNTSNPSVLLAAGLLAKKAVEAGLKVAPHIKTSLAPGSRV 476
                 +  G V+IAAITSCTNTSNPSVL+AAGLLAKKAV  GLK  P +K SLAPGS+V
Sbjct: 417 -GHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLLAKKAVTLGLKRQPWVKASLAPGSKV 475

Query: 477 VTEYLQAAGLLPYLEKLGFGVTAYGCTTCIGNAGDLTPELNEAITRNDLVAAAVLSGNRN 536
           V++YL  A L PYL++LGF +  YGCTTCIGN+G L   +  AI + DL   AVLSGNRN
Sbjct: 476 VSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNSGPLPDPIETAIKKGDLTVGAVLSGNRN 535

Query: 537 FEARIHPNIRANFLASPPLVVAYAIAGNVTRDLMTEPVGTGKGGREIYLGDIWPTSEEIH 596
           FE RIHP ++ N+LASPPLVVAYA+AGN+  +L +EP+G  + G  +YL DIWP+++EI 
Sbjct: 536 FEGRIHPLVKTNWLASPPLVVAYALAGNMNINLASEPIGHDRKGDPVYLKDIWPSAQEIA 595

Query: 597 ALMKYAMDSKVFKINYEQVKKPSKLWAKVKGTKGQVYDWPK-STYIAEPPFFDGFGMEPA 655
             ++  + +++F+  Y +V + +  W  +  T+   Y W + STYI   PFFD     PA
Sbjct: 596 RAVE-QVSTEMFRKEYAEVFEGTAEWKGINVTRSDTYGWQEDSTYIRLSPFFDEMQATPA 654

Query: 656 ATQSSVRNARALGVFGDSVTTDHISPAGSIKESSPAGKYLLANGVLKADFNSYGSRRGNH 715
             +  +  AR L + GDSVTTDHISPAGSIK  SPAG+YL   GV + DFNSYGSRRGNH
Sbjct: 655 PVE-DIHGARILAMLGDSVTTDHISPAGSIKPDSPAGRYLQGRGVERKDFNSYGSRRGNH 713

Query: 716 EVMMRGTFANVRIKNLMLPVKADGSRVEGGVTLHQPSGEALSIYDAAMKYIAEGTPTVVF 775
           EVMMRGTFAN+RI+N M+P       VEGG+T H P  + +SIYDAAM+Y  E TP  V 
Sbjct: 714 EVMMRGTFANIRIRNEMVP------GVEGGMTRHLPDSDVVSIYDAAMRYKQEQTPLAVI 767

Query: 776 GGEEYGTGSSRDWAAKGTQLLGVKAVITRSFERIHRSNLVGMGVLPLQFKGSDSVQTLGI 835
            G+EYG+GSSRDWAAKG +LLG++ VI  SFERIHRSNL+GMG+LPL+F    + +TLG+
Sbjct: 768 AGKEYGSGSSRDWAAKGPRLLGIRVVIAESFERIHRSNLIGMGILPLEFPQGVTRKTLGL 827

Query: 836 VGDETFDIEGIEGELKPQQDVTLVIKRANGDVQRVPLLLRIDTPIEVDYYNHGGILPFVL 895
            G+E  DI  ++  L+P   V + + RA+G  + VP   RIDT  E+ YY + GIL +V+
Sbjct: 828 TGEEKIDIGDLQ-NLQPGATVPVTLTRADGSQEVVPCRCRIDTATELTYYQNDGILHYVI 886

Query: 896 RQLL 899
           R +L
Sbjct: 887 RNML 890