Pairwise Alignments
Query, 1940 a.a., excinuclease ABC subunit A from Cupriavidus basilensis FW507-4G11
Subject, 940 a.a., excinuclease ABC subunit UvrA from Escherichia coli ECRC101
Score = 642 bits (1655), Expect = 0.0
Identities = 401/1009 (39%), Positives = 556/1009 (55%), Gaps = 111/1009 (11%)
Query: 6 IRIRGARQHNLKNLDLDLHTGEMTVVTGPSGSGKSSLVFDTLYAEGQRRYVETFSAYARQ 65
I +RGAR HNLKN++L + ++ VVTG SGSGKSSL FDTLYAEGQRRYVE+ SAYARQ
Sbjct: 4 IEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQ 63
Query: 66 FLDRMDRPQVDRVDGVPPAIAIDQTNPVRSSRSTVGTMTELNDHLKLLYARAAELFDRQT 125
FL M++P VD ++G+ PAI+I+Q + + RSTVGT+TE++D+L+LLYAR E
Sbjct: 64 FLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGE------ 117
Query: 126 AQPVRHDSP---ETIYAELQARAAQGD-PRLVVTFPVELPETTTDAEIEQWLSVSGYTRV 181
+ HD P +T+ + +Q + RL++ P+ + + L+ GY R
Sbjct: 118 PRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRA 177
Query: 182 QAQRVVASPTGPRKV-------LDVVADRFRLGNTEKVRVLEAIEASLKRGSGRVNVYVT 234
+ V + P K+ ++VV DRF++ + R+ E+ E +L+ G V
Sbjct: 178 RIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVV--- 234
Query: 235 DAANEGAQAQVWRFSTGLHSPESDIRYADPQPALFSFNSAYGACETCRGFGRVIGVDLGL 294
A + +A+ FS P + +P LFSFN+ GAC TC G G D
Sbjct: 235 -ADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDR 293
Query: 295 VIPDERKTLRGGAIKPMQTPAWKECQDDLMRYAAKAGIPRDVAWSSLTPAERAWVIDGSP 354
VI + +L GGAI+ + Q L A + W SL+ V+ GS
Sbjct: 294 VIQNPELSLAGGAIRGWDRRNFYYFQ-MLKSLADHYKFDVEAPWGSLSANVHKVVLYGS- 351
Query: 355 DWNGKWNTHW--------------------YGVKRFFDYLESKAYKMHIRVLLSKYRSYT 394
GK N + + ++R + ES A +R L+K+ S
Sbjct: 352 ---GKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA----VREELAKFISNR 404
Query: 395 PCETCGGARLKTEALLWRLGSKPGADAVCAPQKRFAPRGVDWDRTQLEALPGLTVHDLML 454
PC +C G RL+ EA R V + T L A+ +++ M
Sbjct: 405 PCASCEGTRLRREA-----------------------RHVYVENTPLPAISDMSIGHAM- 440
Query: 455 MPIERIRKFFDELTLPSLMLDDALKLLLAEVRTRLKYLCDVGLGYLTLDRQSRTLSGGEV 514
+FF+ L L A K +L E+ RLK+L +VGL YLTL R + TLSGGE
Sbjct: 441 -------EFFNNLKLAGQRAKIAEK-ILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEA 492
Query: 515 QRINLTTALGTSLVKTLFVLDEPSIGLHPRDLNRIVEAMHRLRDAGNTLVVVEHDPSVML 574
QRI L + +G LV ++VLDEPSIGLH RD R++ + LRD GNT++VVEHD +
Sbjct: 493 QRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIR 552
Query: 575 AADRLIDMGPGPGERGGNIIFDG-TPADIRGSGTLTGEYLAGHRQVTDLSRWTPRAVDAA 633
AAD +ID+GPG G GG ++ +G A + +LTG+Y++G R++ P+ A
Sbjct: 553 AADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIE-----VPKKRVPA 607
Query: 634 TPRIVLE--GASEHNLRDVTVEIPLQRLVCVTGVSGSGKSTLLQDVLYPAMARQFGKSTD 691
P VL+ GA +NL+DVT+ +P+ C+TGVSGSGKSTL+ D L+P RQ +T
Sbjct: 608 NPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATI 667
Query: 692 A-PGAFRSLTGAEQVADVVFVDQSPIGKTARSNPASYVGAFDEIRKLFAKAPMALQRSYT 750
A P +R + G E V+ +DQSPIG+T RSNPA+Y G F +R+LFA P + R YT
Sbjct: 668 AEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYT 727
Query: 751 AGMFSFNSGDGRCPTCGGSGFEHVEMQFLSDVYLRCPDCDGRRYRAEILEVKIERALPGQ 810
G FSFN GRC C G G VEM FL D+Y+ C C G+RY E LE+K
Sbjct: 728 PGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKY------- 780
Query: 811 PPRALSVADVLELTVSEAVAYFAGDAAVLRVLQPIVDVGLEYVKLGQPVPTLSGGEAQRL 870
+ ++ +VL++T+ EA +F A+ R LQ ++DVGL Y++LGQ TLSGGEAQR+
Sbjct: 781 --KGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRV 838
Query: 871 KLAGYLAETAQASNTRVKPMPYECKLFMFDEPTTGLHFDDIAKLMRAFGKLLDGGHSLIV 930
KLA L++ L++ DEPTTGLHF DI +L+ KL D G++++V
Sbjct: 839 KLARELSKRGTGQT-----------LYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVV 887
Query: 931 IEHNLDVVRAADWIIDLGPEGGDAGGEVLCVGTPEDVKRCAHSHTGKAL 979
IEHNLDV++ ADWI+DLGPEGG GGE+L GTPE V C SHT + L
Sbjct: 888 IEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFL 936
Score = 520 bits (1338), Expect = e-151
Identities = 285/592 (48%), Positives = 374/592 (63%), Gaps = 52/592 (8%)
Query: 1347 VADTPCADCGGTRLNPVARAVTFDTHPIVAVAQWTVSDTHRWVQGLHLAGREGEIARDVV 1406
+++ PCA C GTRL AR V + P+ A++ ++ + L LAG+ +IA ++
Sbjct: 401 ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKIL 460
Query: 1407 SEIRSRLQFLEEVGLGYLSLDRAAPSLSGGEAQRIRLAAQLGSNLQGVCYVLDEPTIGLH 1466
EI RL+FL VGL YL+L R+A +LSGGEAQRIRLA+Q+G+ L GV YVLDEP+IGLH
Sbjct: 461 KEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLH 520
Query: 1467 PRDNQILLDALRKLGEKGNTLVVVEHDEDTIRCADHIIDIGPGAGKRGGTLVAQGGVAAL 1526
RDN+ LL L L + GNT++VVEHDED IR ADH+IDIGPGAG GG +VA+G + A+
Sbjct: 521 QRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAI 580
Query: 1527 SASADSLTGQFLAQPILHPLQPRREVTPAGKNNEAVPERWLTVHNATKHNLRNVTASIPL 1586
A +SLTGQ+++ +R++ K A PE+ L + A +NL++VT ++P+
Sbjct: 581 MAVPESLTGQYMS--------GKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPV 632
Query: 1587 ARLVAITGVSGSGKSTLARDVLMANLLDAVGRSVMSSPATRRARKAAGSEAPARSQATAR 1646
ITGVSGSGKSTL D L P +R A PA
Sbjct: 633 GLFTCITGVSGSGKSTLINDTLF--------------PIAQRQLNGATIAEPA------- 671
Query: 1647 TEPRRKLEVTHNWQGCESITGYESIDRVLEVDQTPIGKTPRSCPATYIGVWDTIRKLFAQ 1706
P R I G E D+V+++DQ+PIG+TPRS PATY GV+ +R+LFA
Sbjct: 672 --PYR------------DIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAG 717
Query: 1707 TLEAKARGYSASRFSFNTGDGRCPACEGQGVRTIGMSFLPDVKVHCDVCHGQRFNPETLA 1766
E++ARGY+ RFSFN GRC AC+G GV + M FLPD+ V CD C G+R+N ETL
Sbjct: 718 VPESRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLE 777
Query: 1767 VTWRGKNIGDVLTMEIDEAVEFFSAMSNIAHPLQLMKDVGLGYLTLGQPSPTLSGGEAQR 1826
+ ++GK I +VL M I+EA EFF A+ +A LQ + DVGL Y+ LGQ + TLSGGEAQR
Sbjct: 778 IKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQR 837
Query: 1827 IKLVTELSKVRDDITRRGQQAPHTLYVLDEPTVGLHMADVAKLIRVLHRLADGGHSVVVI 1886
+KL ELSK RG TLY+LDEPT GLH AD+ +L+ VLH+L D G+++VVI
Sbjct: 838 VKLARELSK-------RG--TGQTLYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVVI 888
Query: 1887 EHDLDVIAEADWILDLGPEGGVAGGGIVAATDPEGLVRVRASHTGAALAPVL 1938
EH+LDVI ADWI+DLGPEGG GG I+ + PE + ASHT L P+L
Sbjct: 889 EHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML 940
Score = 196 bits (499), Expect = 9e-54
Identities = 109/296 (36%), Positives = 167/296 (56%), Gaps = 12/296 (4%)
Query: 1016 DVVRIVNAHEHNLKALNVDIPHGKFNVITGVSGSGKSTLAFDILFHEGQRRYLESLNAYA 1075
D + + A HNLK +N+ IP K V+TG+SGSGKS+LAFD L+ EGQRRY+ESL+AYA
Sbjct: 2 DKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYA 61
Query: 1076 RSIVQPAGRPEVDAVYGIPPTVAIEQRLSRGGRKSTVATTSEVWHFLRLMYVKLGIQHCI 1135
R + +P+VD + G+ P ++IEQ+ + +STV T +E+ +LRL+Y ++G C
Sbjct: 62 RQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCP 121
Query: 1136 HDGTPVTSQSPESIAAQLLRDYKGQHVGLLAPLVVSRKGVYTDLAKWAKARGNTHLRVDG 1195
P+ +Q+ + +L +G+ + LLAP++ RKG +T + ++G R+DG
Sbjct: 122 DHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDG 181
Query: 1196 EFLPVDPWPRLDRFREHTIELPVGDIIVSADNEAALRALLGQALEAGKGVMHLLAPLDGL 1255
E + P+L+ ++HTIE+ V V D L ALE G ++A +D
Sbjct: 182 EVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTA-VVADMDDP 240
Query: 1256 QHAMGNGGTARVGSTTVFSTKRACPVCSTSYPELDPRLFSYNSKHGWCTSCVGTGL 1311
+ +FS ACP+C S EL+PRLFS+N+ G C +C G G+
Sbjct: 241 K-----------AEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGV 285
Score = 134 bits (338), Expect = 4e-35
Identities = 108/355 (30%), Positives = 169/355 (47%), Gaps = 59/355 (16%)
Query: 786 CPDCDGRRYRAEILEVKIERALPGQPPRALSVADVLELTVSEAVAYF-----AGDAAVL- 839
C C+G R R E V +E P A+S ++++ A+ +F AG A +
Sbjct: 406 CASCEGTRLRREARHVYVENT----PLPAIS-----DMSIGHAMEFFNNLKLAGQRAKIA 456
Query: 840 -RVLQPI-------VDVGLEYVKLGQPVPTLSGGEAQRLKLAGYLAETAQASNTRVKPMP 891
++L+ I V+VGL Y+ L + TLSGGEAQR++LA +
Sbjct: 457 EKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV-------- 508
Query: 892 YECKLFMFDEPTTGLHFDDIAKLMRAFGKLLDGGHSLIVIEHNLDVVRAADWIIDLGPEG 951
+++ DEP+ GLH D +L+ L D G+++IV+EH+ D +RAAD +ID+GP
Sbjct: 509 ----MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGA 564
Query: 952 GDAGGEVLCVGTPEDVKRCAHSHTGKALLQYDRAVGHAFVAQDAGVPLQAALRAARARRA 1011
G GGEV+ G E + S TG+ + + + + R
Sbjct: 565 GVHGGEVVAEGPLEAIMAVPESLTGQYMSG------------------KRKIEVPKKRVP 606
Query: 1012 IEGEDVVRIVNAHEHNLKALNVDIPHGKFNVITGVSGSGKSTLAFDILFHEGQRRYLESL 1071
E V+++ A +NLK + + +P G F ITGVSGSGKSTL D LF QR+ L
Sbjct: 607 ANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQ----L 662
Query: 1072 NAYARSIVQPAGRPEVDAVYGIPPTVAIEQRLSRGGRKSTVATTSEVWHFLRLMY 1126
N +I +PA ++ + + I+Q +S AT + V+ +R ++
Sbjct: 663 N--GATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELF 715
Score = 127 bits (320), Expect = 5e-33
Identities = 85/254 (33%), Positives = 122/254 (48%), Gaps = 42/254 (16%)
Query: 1291 PRLFSYNSKHGWCTSCVGTGLTLTREQRAAYDDTVMADDNRGREQTLPSEQQEPDDVADT 1350
P FS+N + G C +C G G+ + E D+
Sbjct: 728 PGRFSFNVRGGRCEACQGDGV-------------------------IKVEMHFLPDIY-V 761
Query: 1351 PCADCGGTRLNPVARAVTFDTHPIVAVAQWTVSDTHRWVQGLHLAGREGEIARDVVSEIR 1410
PC C G R N + + I V T+ + + D V +
Sbjct: 762 PCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF--------------DAVPALA 807
Query: 1411 SRLQFLEEVGLGYLSLDRAAPSLSGGEAQRIRLAAQLGSNLQG-VCYVLDEPTIGLHPRD 1469
+LQ L +VGL Y+ L ++A +LSGGEAQR++LA +L G Y+LDEPT GLH D
Sbjct: 808 RKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFAD 867
Query: 1470 NQILLDALRKLGEKGNTLVVVEHDEDTIRCADHIIDIGPGAGKRGGTLVAQGGVAALSAS 1529
Q LLD L KL ++GNT+VV+EH+ D I+ AD I+D+GP G GG ++ G ++
Sbjct: 868 IQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAEC 927
Query: 1530 ADSLTGQFLAQPIL 1543
S T +FL +P+L
Sbjct: 928 EASHTARFL-KPML 940
Score = 59.3 bits (142), Expect = 2e-12
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 6/115 (5%)
Query: 5 VIRIRGARQHNLKNLDLDLHTGEMTVVTGPSGSGKSSLVFDTLYAEGQRRYVETFSAYAR 64
V+++ GAR +NLK++ L L G T +TG SGSGKS+L+ DTL+ QR+ A
Sbjct: 612 VLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPA 671
Query: 65 QFLDRMDRPQVDRVDGVPPAIAIDQTNPVRSSRSTVGTMTELNDHLKLLYARAAE 119
+ D D+V I IDQ+ R+ RS T T + ++ L+A E
Sbjct: 672 PYRDIQGLEHFDKV------IDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE 720
Score = 57.0 bits (136), Expect = 1e-11
Identities = 41/120 (34%), Positives = 61/120 (50%), Gaps = 23/120 (19%)
Query: 636 RIVLEGASEHNLRDVTVEIPLQRLVCVTGVSGSGKSTLLQDVLY-----------PAMAR 684
+I + GA HNL+++ + IP +L+ VTG+SGSGKS+L D LY A AR
Sbjct: 3 KIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYAR 62
Query: 685 QFGKSTDAPGAFRSLTGAEQVADVVFVDQSPIGKTARSNPASYVGAFDEI----RKLFAK 740
QF + P + E ++ + ++Q K+ NP S VG EI R L+A+
Sbjct: 63 QFLSLMEKP----DVDHIEGLSPAISIEQ----KSTSHNPRSTVGTITEIHDYLRLLYAR 114
Score = 52.0 bits (123), Expect = 4e-10
Identities = 40/145 (27%), Positives = 61/145 (42%), Gaps = 29/145 (20%)
Query: 1567 LTVHNATKHNLRNVTASIPLARLVAITGVSGSGKSTLARDVLMANLLDAVGRSVMSSPAT 1626
+ V A HNL+N+ IP +L+ +TG+SGSGKS+LA D L A
Sbjct: 4 IEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAE--------------- 48
Query: 1627 RRARKAAGSEAPARSQATARTEPRRKLEVTHNWQGCESITGYESIDRVLEVDQTPIGKTP 1686
+ R A AR + +P +V H E + + ++Q P
Sbjct: 49 GQRRYVESLSAYARQFLSLMEKP----DVDH----------IEGLSPAISIEQKSTSHNP 94
Query: 1687 RSCPATYIGVWDTIRKLFAQTLEAK 1711
RS T + D +R L+A+ E +
Sbjct: 95 RSTVGTITEIHDYLRLLYARVGEPR 119
Score = 30.8 bits (68), Expect = 0.001
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 5/41 (12%)
Query: 1703 LFAQTLEAKARGYSASR-----FSFNTGDGRCPACEGQGVR 1738
LF+ GYS FSFN G CP C+G GV+
Sbjct: 246 LFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQ 286