Pairwise Alignments

Query, 355 a.a., 5-methyltetrahydrofolate--homocysteine methyltransferase from Cupriavidus basilensis FW507-4G11

Subject, 1227 a.a., homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent from Escherichia coli BL21

 Score =  385 bits (988), Expect = e-111
 Identities = 189/334 (56%), Positives = 246/334 (73%), Gaps = 4/334 (1%)

Query: 17  TRAANLPALLRERILILDGAMGTMIQRYKLTEADYRGERFAGHHVDVKGNNELLLLSRPQ 76
           ++   L A L ERIL+LDG MGTMIQ Y+L EAD+RGERFA    D+KGNN+LL+LS+P+
Sbjct: 3   SKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPE 62

Query: 77  VISEIHEQYLAAGADLIETNTFGATGVAQEDYKMADLAYEMNVVAARLAREACDKYS--T 134
           VI+ IH  Y  AGAD+IETNTF +T +A  DY+M  L+ E+N  AA+LAR   D+++  T
Sbjct: 63  VIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTART 122

Query: 135 PDKPRFVAGAFGPTPKTASISPDVNDPGARNVTFEELRCSYYEQGKGLLEGGADVFLVET 194
           P+KPR+VAG  GPT +TASISPDVNDP  RN+TF+ L  +Y E  K L+EGGAD+ L+ET
Sbjct: 123 PEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVAAYRESTKALVEGGADLILIET 182

Query: 195 IFDTLNAKAALFAIDQLFEDTGERLPVMISGTVTDASGRILSGQTVEAFWNSLRHARPIT 254
           +FDTLNAKAA+FA+   FE  G  LP+MISGT+TDASGR LSGQT EAF+NSLRHA  ++
Sbjct: 183 VFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALS 242

Query: 255 FGLNCALGATLMRPYIAELAKICDAAVSCYPNAGLPNPMSDTGFDETPEVTSSLVEEFAA 314
           FGLNCALG   +R Y+ EL++I +  V+ +PNAGLPN   +  +D   +  +  + E+A 
Sbjct: 243 FGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGE--YDLDADTMAKQIREWAQ 300

Query: 315 SGLVNLVGGCCGTTPEHIAAIAERVASKKPRTWP 348
           +G +N+VGGCCGTTP+HIAA++  V    PR  P
Sbjct: 301 AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP 334