Pairwise Alignments

Query, 314 a.a., methylenetetrahydrofolate reductase from Caulobacter crescentus NA1000

Subject, 296 a.a., 5,10-methylenetetrahydrofolate reductase from Escherichia fergusonii Becca

 Score =  292 bits (748), Expect = 6e-84
 Identities = 140/286 (48%), Positives = 196/286 (68%), Gaps = 10/286 (3%)

Query: 18  ERTGRPRVSFEFFPPKTPQMEESLWQAITRLAPLDPAFVSVTYGAGGSTRERTHRTVKRI 77
           E  G+  VSFEFFPP+T +ME++LW +I RL+ L P FVSVTYGA    R+RTH  +K I
Sbjct: 18  EVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGI 77

Query: 78  LDETSLKPAAHLTCVGASREEVDEVIREYWETGVRHIVSLRGDPPPGEGGIGGVYVPRAD 137
            D T L+ A HLTC+ A+  E+  + R+YW  G+RHIV+LRGD PPG G        + +
Sbjct: 78  KDRTGLEAAPHLTCIDATPAELRTIARDYWNNGIRHIVALRGDLPPGSG--------KPE 129

Query: 138 GYANATELTKAVRAIAPFEVLVGVYPEKHPESPSLEHDIDVLKQKVDAGATLGISQFFFD 197
            YA+  +L   ++ +A F++ V  YPE HPE+ S + D+  L++KVDAGA   I+QFFFD
Sbjct: 130 MYAS--DLVTLLKEVADFDISVAAYPEVHPEAKSAQADLLNLRRKVDAGANRAITQFFFD 187

Query: 198 LDAFLRFVDKVRAAGITIPIVPGIMPVTNFAGLKKMAAACQTAIPSWLGNLFDGLENDAE 257
           ++++LRF D+  +AGI + I+PGI+PV+NF   KK A      IP+W+  +FDGL++DAE
Sbjct: 188 VESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFDGLDDDAE 247

Query: 258 TRRLIACSVAAEMCAKLQEQGFEDFHFYTLNRADLVYAICRVLGVR 303
           TR+L+  ++A +M   L  +G +DFHFYTLNRA++ YAIC  LGVR
Sbjct: 248 TRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVR 293