Pairwise Alignments
Query, 1431 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1351 a.a., Signal transduction histidine kinase from Echinicola vietnamensis KMM 6221, DSM 17526
Score = 509 bits (1312), Expect = e-148
Identities = 362/1338 (27%), Positives = 644/1338 (48%), Gaps = 93/1338 (6%)
Query: 133 IASDQSIWLW-DNNNGCRRVVYQDGQFSSQAYKKELGNLSSDKVLFVYESN-DSPGHVWI 190
I D+ ++W NG R DG + + + E S F+Y + DS G +W+
Sbjct: 48 ILQDRQGFMWFGTKNGLNRY---DGH-NFKVFNPETSKKSGLADSFIYGLHEDSNGIIWV 103
Query: 191 GTKQGLWKY--------HDGKLEAMDTQ--GESWEHIFSYDQYTCIITGKKEIYRHSLSN 240
GT G++ Y H K+ + Q G E + ++++ ++
Sbjct: 104 GTAHGMYTYNSSTESFTHFDKVSNLGNQIDGSVGEITEDLQGNIYFAVNNRGLFQYQVAE 163
Query: 241 NRLEKIASLTE----LGDTGVITGSLRLQHQ-WVMFTATGSYILDPVTGKLRRFSRLN-- 293
+ L + ++++ L D + + + WV + G + P T K +++ +
Sbjct: 164 DSLFQYQAISKTNVNLHDNNTTNVLVDEKGELWVSNSRLGVHKFLPKTKKFKQYLTHSEV 223
Query: 294 IKNGNVTRDNKGNAWVHNYTG-NVWYVNTSTGDIKHF--QFLSSEHLGYIDVERYSIIHD 350
IK + ++ GN + VW ++ + G +K + + ++L D+++ S
Sbjct: 224 IKAAVLQMEDHGNNLLLGTKDLGVWVMDKNNGHVKPLLTKAPNGKNLFIRDLQKIS---- 279
Query: 351 SRDIIWITTYGNGLFAYDLNTGDLQHFTFEVSHSSHINSNYLQYIIEDRSGGIWVSSEFS 410
+ +WI T +GLF YDL +HF ++ I+ N + I D GG+W+ + F
Sbjct: 280 -ENELWIATE-SGLFIYDLEKHKFKHFKENLNDPYSISDNAIYCISRDIEGGMWIGTYFG 337
Query: 411 GLSHLEILNKGTLRIYPNGEDASDRSNTIRMLLRGKNGNVYMANRMGTLYEYDAD----- 465
G++ L + YP + +R GK+G +++ L +YD +
Sbjct: 338 GVNFLPNHPTKFKKHYPIPNSNTISGQRVREFEEGKDGTIWIGTEDAGLNQYDPESETYL 397
Query: 466 --LKNILRREKFTHNVYSMCEDNEGQLWLG-------MRGIGLRIGADQWYRYNSKDNNS 516
L N HNV+ + + E +LW+G + + L + ++S N
Sbjct: 398 HYLPNNSSNSLSYHNVHGLAK-RENELWIGTVTFATGLNRMNLNTNKIETIPFHS--NLD 454
Query: 517 LSNDN-VYLIYRDRKGRMWIGTFGGGLNLAVKTGNGYQFKHFFQDSYGEKRVRVIQEDRN 575
+DN ++ I D+ ++W+GT G L L + D G + + + ED
Sbjct: 455 TPDDNEIHSILVDKNKQVWLGTVVGLLKLDEENNTVNSI-----DKIGNRFIYDMIEDHK 509
Query: 576 GMMWVGT-NNGIYIFHPDSLINSPKNYVLYNHVNETFPSNEIRCLVNDHEGNMWIGTTGA 634
G +W+GT +NG+ ++P++ + Y+ P + + D + +WI T G
Sbjct: 510 GNLWLGTYSNGLVKYNPNT--QEMRTYLPDPKNPNALPHYSVINIFQDSQKRIWIATEGG 567
Query: 635 GFAICYPGNDYQHLTFDCYSIKDGLPNGVIQSIVEDQDNKMWIATEYGISRFTLATKQIE 694
GF I +D F ++ +G P+ +I I+ED +WI G+ F T +
Sbjct: 568 GFCIYNEKSD----DFTVFNTDNGFPSNIIYKILEDISGHLWITCSRGLLEFNPQTTEYR 623
Query: 695 NYYFSSHTLGNVYSENTACINADGRLLFGTNYGLVVLDANKVENMEKLASTVFTGLHING 754
+ + + ++ + DG L FG G + D + E E VFTG+ I
Sbjct: 624 LFTKDNGLMPYPFNYKSGFRAKDGTLYFGCLNGFISFDPREFEPYEYDPPVVFTGIQIFN 683
Query: 755 AHMLPGMDDSPLNETMSYTGQLNLKHYQNSFVIAFSTFNFL-SGASKYSYRMPPYDSEWS 813
+ G ++S LN +++ T ++ LKH Q+S F+ ++ S A Y+Y+M +D W+
Sbjct: 684 TPVPIGGENSILNASITNTSEITLKHDQSSLSFDFAALSYTASDALPYAYKMEGFDKTWT 743
Query: 814 IPSAQNLATYRNLPPGKYQLQVKACNVAGVWGE-ESTMEIVIAPPFWQTTWAYLIY---- 868
Y LPPG Y L++K ++ G W + E+ + I I PPFW+T WAY Y
Sbjct: 744 YLPQNQRINYSYLPPGDYTLKIKTADIFGEWSDREAMLHITILPPFWKTNWAYTAYTLLF 803
Query: 869 -LVFIGIVCYFSFHIIRKFNRLRNRIAVEKQLTEY--KLEFFTNISHEFRTPLTLIQGAL 925
++ GI+ ++ I R+ R+ EKQ Y K+EFFTNI+HE RTPLTLI+G L
Sbjct: 804 AIMLYGILKFYKDRIHRRQAAAFKRLEDEKQREIYQSKIEFFTNITHEIRTPLTLIKGPL 863
Query: 926 NKLINIENPPK-EMQRPLKTMDKSTQRMLRLINQLLEFRKMQKNKLALSLEETDVIAFLY 984
++N EN E++ L M+K+T R++ L N+LL+FRK + L+ ++ L
Sbjct: 864 ESILNKENAINPEIKESLWIMNKNTNRLIELSNELLDFRKTENKGFTLNFTRNEIGKLLE 923
Query: 985 EIFLSFKDTSESKNIDFSFEPSQPAYKMFIDKGNLDKVTYNLLSNAFKYTPSNGKIIFKI 1044
+IF+ FK ++E + ++F F S + +D+ KV NLLSNA K S ++ ++
Sbjct: 924 DIFIRFKGSAEQQQVNFHFTGSDAPFFADVDREAFTKVISNLLSNAIKNAESTAQL--EM 981
Query: 1045 DIQEDKQQLRIQVIDNGIGIPKEKRSELFKRFMQSSFSHSS-----VGVGLHLTHELVQV 1099
I + ++ V ++G I E R ++F+ F Q + G+GL L L ++
Sbjct: 982 AISPAEAHFKVIVSNDGHLISPENREKIFEPFFQEGNEFNKPNTTGTGLGLPLARSLAEM 1041
Query: 1100 HKGNISYDEN-EGGGSVFTVLLPTNSDIYQEKDFLIPNQLLTEEEEQHSKDFLRNETSED 1158
H G++ D + + F + LP ++K+ + ++ E+ +
Sbjct: 1042 HGGSLHVDPDYPQNRNTFVLDLPI-----KQKNTIKITEIPAEQPAP--------DRPTK 1088
Query: 1159 TFQPPVDPLNKRKVLIIEDDTDIREFLREEIGVYFEVEVAADGTSGFEKASTYDADLIVC 1218
T + P +K +L++ED+ ++++FL +++ + V A +G G ++ DL++
Sbjct: 1089 TTKSPKPAASKGAILVVEDNKELQKFLYDQLKEEYHVYRAENGQDGIQQLKDKPIDLVIT 1148
Query: 1219 DVLMPGMNGFEVTRKLKNEFTTSHIPIILLTALNIEEKYQEGIESGADAYITKPFNVSLL 1278
DV+MP M+GF +K++ SHIP+I+LTA N + EG+E GAD Y+ KPF++ L
Sbjct: 1149 DVMMPVMDGFTFCDTIKSDVNFSHIPVIMLTAKNTLQSKIEGMEMGADVYLEKPFSIDHL 1208
Query: 1279 LARIFKLIELRDKLRQKYSNEPGLAHSIICTNDKDQKFSVKLNEVLNEHMTDTDFSVNDF 1338
++ L+ RD++RQ ++N+P + I D++F + NE + E++++ F VN+
Sbjct: 1209 GLQVKNLLHYRDQVRQAFANQPMVNVETIAHTRADEEFLSQANEAILENLSNERFGVNEM 1268
Query: 1339 AGIMGLGRTVFYKKVRGVTGYSPYEYLRVMRMKKAAEMLLTEDLTIAEVAYSVGINDPFY 1398
A I+ + ++ +K++GV+ +P Y+R++R+KKAAEML + T+ E++ VG N P Y
Sbjct: 1269 ADILCMSQSSLLRKIKGVSKMTPNGYIRLVRLKKAAEMLQSGQYTVTEISEKVGFNSPSY 1328
Query: 1399 FSKCFKNQFGVSPSAYRK 1416
FSKCF+ QFG P + K
Sbjct: 1329 FSKCFQKQFGELPKDFTK 1346
Score = 154 bits (389), Expect = 6e-41
Identities = 160/633 (25%), Positives = 273/633 (43%), Gaps = 67/633 (10%)
Query: 5 LLIFAFLSFYLSSVHASVEIRSNKLTTGDGLANNSIRYMFQDSKGFMWMGTVNGLSYYDG 64
LL+F +L S + +T DGL+ +++ + QD +GFMW GT NGL+ YDG
Sbjct: 10 LLLFFCTGLFLRSAAQGQDYYFEHITMDDGLSGSTVLSILQDRQGFMWFGTKNGLNRYDG 69
Query: 65 NSFVSIYPDPNLPISLADPRIRNMEEDSNGFLWIATLSSLYSCYDLKHGRFVDFTGCGEY 124
++F P+ + LAD I + EDSNG +W+ T +Y+ Y+ F F
Sbjct: 70 HNFKVFNPETSKKSGLADSFIYGLHEDSNGIIWVGTAHGMYT-YNSSTESFTHFDKVSNL 128
Query: 125 KQSYSKKI--IASD--QSIWLWDNNNGC-RRVVYQDGQFSSQAYKKELGNLSSDKVLFVY 179
+ I D +I+ NN G + V +D F QA K NL + V
Sbjct: 129 GNQIDGSVGEITEDLQGNIYFAVNNRGLFQYQVAEDSLFQYQAISKTNVNLHDNNTTNVL 188
Query: 180 ESNDSPGHVWI-GTKQGLWKY------------HDGKLEAMDTQGESWEHIFSYDQYTCI 226
D G +W+ ++ G+ K+ H ++A Q E D +
Sbjct: 189 V--DEKGELWVSNSRLGVHKFLPKTKKFKQYLTHSEVIKAAVLQME--------DHGNNL 238
Query: 227 ITGKKE--IYRHSLSNNRLEKIASLTELGDTGVITGSLRLQHQ--WVMFTATGSYILDPV 282
+ G K+ ++ +N ++ + + G I ++ W+ T +G +I D
Sbjct: 239 LLGTKDLGVWVMDKNNGHVKPLLTKAPNGKNLFIRDLQKISENELWIA-TESGLFIYDLE 297
Query: 283 TGKLRRFSRLNIKNGN---------VTRDNKGNAWVHNYTGNVWYV-NTSTGDIKHFQFL 332
K + F N+ + ++RD +G W+ Y G V ++ N T KH+
Sbjct: 298 KHKFKHFKE-NLNDPYSISDNAIYCISRDIEGGMWIGTYFGGVNFLPNHPTKFKKHYPIP 356
Query: 333 SSEHLGYIDVERYSIIHDSRD-IIWITTYGNGLFAYDLNTGDLQHFTFEVSHSSHINSNY 391
+S I +R + +D IWI T GL YD + H+ ++SS+ S +
Sbjct: 357 NS---NTISGQRVREFEEGKDGTIWIGTEDAGLNQYDPESETYLHYL--PNNSSNSLSYH 411
Query: 392 LQYIIEDRSGGIWVSSE--FSGLSHLEILNKGTLRIYP--NGEDASDRSNTIRMLLRGKN 447
+ + R +W+ + +GL+ + LN + P + D D N I +L KN
Sbjct: 412 NVHGLAKRENELWIGTVTFATGLNRMN-LNTNKIETIPFHSNLDTPD-DNEIHSILVDKN 469
Query: 448 GNVYMANRMGTLYEYDADLKNILRREKFTHN-VYSMCEDNEGQLWLGMRGIGL-----RI 501
V++ +G L + D + + +K + +Y M ED++G LWLG GL
Sbjct: 470 KQVWLGTVVG-LLKLDEENNTVNSIDKIGNRFIYDMIEDHKGNLWLGTYSNGLVKYNPNT 528
Query: 502 GADQWYRYNSKDNNSLSNDNVYLIYRDRKGRMWIGTFGGGLNLAVKTGNGYQFKHFFQDS 561
+ Y + K+ N+L + +V I++D + R+WI T GGG + F F D+
Sbjct: 529 QEMRTYLPDPKNPNALPHYSVINIFQDSQKRIWIATEGGG--FCIYNEKSDDFTVFNTDN 586
Query: 562 -YGEKRVRVIQEDRNGMMWVGTNNGIYIFHPDS 593
+ + I ED +G +W+ + G+ F+P +
Sbjct: 587 GFPSNIIYKILEDISGHLWITCSRGLLEFNPQT 619
Score = 39.7 bits (91), Expect = 2e-06
Identities = 28/121 (23%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 607 VNETFPSNEIRCLVNDHEGNMWIGTTGAGFAICYPGNDYQHLTFDCYSIKDGLPNGVIQS 666
+++ + + ++ D +G MW GT Y G++++ + S K GL + I
Sbjct: 36 MDDGLSGSTVLSILQDRQGFMWFGTKNG--LNRYDGHNFKVFNPET-SKKSGLADSFIYG 92
Query: 667 IVEDQDNKMWIATEYGISRFTLATKQIENYYFSSHTLGNVYSENTACINAD--GRLLFGT 724
+ ED + +W+ T +G+ + +T+ ++ S+ LGN + I D G + F
Sbjct: 93 LHEDSNGIIWVGTAHGMYTYNSSTESFTHFDKVSN-LGNQIDGSVGEITEDLQGNIYFAV 151
Query: 725 N 725
N
Sbjct: 152 N 152
Score = 36.2 bits (82), Expect = 2e-05
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 632 TGAGFAICYPGNDY--QHLTFDCYSIKDGLPNGVIQSIVEDQDNKMWIATEYGISRF 686
TG G DY +H+T D DGL + SI++D+ MW T+ G++R+
Sbjct: 16 TGLFLRSAAQGQDYYFEHITMD-----DGLSGSTVLSILQDRQGFMWFGTKNGLNRY 67