Pairwise Alignments

Query, 598 a.a., putative chloride channel protein (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482

Subject, 418 a.a., voltage-gated ClC-type chloride channel ClcB from Escherichia coli ECRC98

 Score =  136 bits (342), Expect = 2e-36
 Identities = 110/438 (25%), Positives = 191/438 (43%), Gaps = 42/438 (9%)

Query: 28  LILSFLVGIFTAIAALFLKFLIHQIQNFLTNNFNATSAN-------YLYLVYPVIGIFLA 80
           L+++ +VGI  A A    +  +  ++    NN + +  N       +  L+ P +G   A
Sbjct: 5   LLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAA 64

Query: 81  GWFVRNIVK--DDISHGVTKILYAISRRQGRIKRHNIWSSTIASAITIGFGGSVGAEAPI 138
           G  +    K      H  T  + A+ +  G+         ++AS + +  G ++G E  +
Sbjct: 65  GLLLMGWQKFTQQRPHAPTDYMEAL-QTDGQFDYAASLVKSLASLLVVTSGSAIGREGAM 123

Query: 139 VLTGSAIGSNLGSVFKMEHRTLMLLVGCGAAGAIAGIFKAPIAGLVFTLEVLMIDLTMSS 198
           +L  +   S     F    +   L + CGAA  +A  ++AP+AG +F  EVL   + ++S
Sbjct: 124 ILLAALAASCFAQRFT-PRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLAS 182

Query: 199 LLPLLISAVTAATVSYITTGTEA-MFKFNLDQAFELERIPYVILLGIFCGLISLYFTRAM 257
           L P++ISAV A  VS +   ++A ++   L    +      +I  G+  GL        M
Sbjct: 183 LGPVIISAVVALLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLM 242

Query: 258 NSIEGVFGKLK-NPYQKLAFGGVMLSVLIFLFPPLYGEGYDTIELLLNGTSAAEWDTVMN 316
           N+    F  LK  P  +LA GG+++ +L    P ++G GY T++  L             
Sbjct: 243 NACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPP--------- 293

Query: 317 NSMFYGYGNLLQVYLMLIILLKVFASSATNGGGGCGGIFAPSLYLGCIAGFVFSHFSNDF 376
                     L + +  I L K+ A  A++G G  GG+F P+L++G   G ++       
Sbjct: 294 ----------LLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGR----- 338

Query: 377 AFSAYLPEKN-----FALMGMAGVMSGVMHAPLTGVFLIAELTGGYDLFLPLMIVSVSSY 431
           +   + P+         L GMA +++   HAP+    +I E+TG Y L   L+I  V + 
Sbjct: 339 SLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIAS 398

Query: 432 LTIIAFEPHSIYSMRLAK 449
           +        SIY    A+
Sbjct: 399 VISRTLHRDSIYRQHTAQ 416