Pairwise Alignments
Query, 1330 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1450 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Score = 414 bits (1064), Expect = e-119
Identities = 366/1446 (25%), Positives = 627/1446 (43%), Gaps = 176/1446 (12%)
Query: 29 KYIGLEDGLNNQKIYHIQKDRRGYMWFLTQEGVDRYDGKHIKHYTFSDDSMKLDSRIALN 88
K+ + DG++ + I +D++G++WF T G++++DG K+Y S + + ++
Sbjct: 26 KHYSVNDGMSQGIVQTIIQDKKGFLWFGTWNGLNKFDGYTFKNYKTSYKDGYILNTNRIS 85
Query: 89 WLYMDQEDVLWVIGQKGRIFRYDSQHDKFE--LAYVHPELIRNKFQ-------------- 132
+ + +W GR++ +D+Q +KF L V +I N +
Sbjct: 86 QIAETKYGDIWCQAYDGRVYMFDNQTEKFIDILGSVAETMITNNYADHIYTLSKGISWIT 145
Query: 133 ----------------------AFLDYGYLDKNDHIWLCYKDTI--TWYNIRTGTTQHMP 168
+ + K D I+ ++D+ W G +
Sbjct: 146 FQNECAAIRIDDQLCKQGKGITLYSSFKQNLKGDKIYTVFEDSEGDEWILTNKGISIIGK 205
Query: 169 KPVDG--AISTIEQADGGHFFIGTGSGLFCVGIEKGELKQIPDEVVKSIVTPVHELYYHT 226
K VD I++ADG + + L + + K I S++ V + +T
Sbjct: 206 KQVDSDFPFQYIKEADGIIYLVSQSDKLASYNFKTRQFKFIEIPYHVSMINEVKKFDSNT 265
Query: 227 VSKQLFVGSYKEGILIYDIGKTQ----KITPCYAPNNVEVNQIVALNADELLIATGGKGV 282
+ + + G++IY I + + I P+NV V + + EL I GV
Sbjct: 266 L-----LLATDNGLIIYKIKEKEFQLIDIRTSTQPSNV-VQSVYQDHYKELWIFPQTTGV 319
Query: 283 YKLNVNTCKSEPYITADYSSYNGMNGNNINDIYVDEEERIWLANYPTGITIRNNRYGRYD 342
+ N +T K ++ N N I+ D + +W+ ++ +
Sbjct: 320 IRYNPST-KEMQHLFTPADEVIRYERKNKNVIFEDRQHTLWVLPPEGNLSYYDRENKELK 378
Query: 343 LIKHSLGNNRSLVNDQVHDVIEDSDGDLWFATSNGI---SFY------------------ 381
+ N +S+ + V D+ G+ W ++ GI SF+
Sbjct: 379 PMLKDSNNPKSVFSPLVRFYTLDNQGNCWLTSTRGIYKLSFFPHTYNLVHIDNGFETRAF 438
Query: 382 --QTDTREWCS-----------------FFSSFDPVPDDENHIFLALC--EVSPGVIWAG 420
+ R W S + + + D+ C E G IW G
Sbjct: 439 LCDNEKRLWVSSKAQMIRVYQPDGQLEGYLTPQGKISKDKQSFTSVYCFLEDHEGNIWIG 498
Query: 421 GFTSGIYKIEKKKGFKISYLS-------PAAIAGIRPDQYIYDIKKDSSGDVWSGGYYHL 473
+GIY ++KK S P +++G +Y I +DS +W G Y
Sbjct: 499 TKENGIYLLKKKSPDSYSVQQFTHQPNMPYSLSG----NSVYSIFQDSHKRIWIGCYGG- 553
Query: 474 KRINLETKN-------------VRLYPG--VSSITTILEKNARQMWIGTRMGLY----QL 514
INL T N ++ YP S + I E + IGT GL Q
Sbjct: 554 -GINLLTYNKDGKTEFIHSDNELKNYPTGYASKVRHISEAPGGVLLIGTTNGLLTFSNQF 612
Query: 515 DKQSGVYRY-------IDLPVESPYICALYQREDGILYIG--TRGAGLLVYD--INKKKF 563
++ + Y I + + Y + YI T G +V ++ K
Sbjct: 613 ERPEEIKFYRNCCESGISTSLSGNDVMHTYTDKQKRTYIASFTGGISQIVSKNLLSNKIE 672
Query: 564 IHQYRTDNCALISDNIYTIIPRQDENLLMGTENGITIYSPKDHFFRNWTREQGLMSVNFN 623
Y TD+ L SD + + Q NL + +EN I+ + + F N+ +F+
Sbjct: 673 FKTYTTDD-GLASDLVQAMQEDQQGNLWILSENAISKFDAQRKTFENYGLNSLHQEFSFS 731
Query: 624 AGSATTYSNSTLVFGGNDGAVKFPTDIEIPEPYYSRLLLRDFMIAYHPVYPGDDGSPLKK 683
+ + + +VFG + G ++ + Y ++ + G
Sbjct: 732 EAAPVINARNQIVFGTDKGFIEISSKEMQKSSYVPPIVFTGLKV---------QGQSSVI 782
Query: 684 DINETDCLELAYGQNTFSLDVASINYDYPSNILYSWKIDGYHKEWTRPSQDNRIVVRNLP 743
I++ + L L Q + A+++Y I Y++++ G +EW ++ NLP
Sbjct: 783 AIDDLEELRLTPSQRNVTFQFAALDYVDSKEIRYAYRLKGLEEEWHDGDKNRSASYINLP 842
Query: 744 PGSYTLQIRTVSNEEKYKTYETRSIQIIITPPVWASMWAMVGYAILVVL----IMIIIFR 799
G Y LQI++ +++ + R++ I + P W + WA + Y IL VL I+ ++F
Sbjct: 843 NGKYKLQIKSTNSDGVWMD-NIRTLSINVLPTFWETGWAWLLYVILFVLFTGSIVYVLFY 901
Query: 800 VIMLHKQ----KKISDEKTRFFINTAHDIRTPLTLIKAPLEEVVENHMVAEKALPHMNMA 855
+ L Q +++S+ K RFF + +H++RTPLTLI +P+ EV+EN ++ A H+ +
Sbjct: 902 IYRLRHQVDIEQQLSNIKLRFFTDISHELRTPLTLISSPVNEVLENEDLSATAREHLTVV 961
Query: 856 LKNVNTLLQLTTNLINFERIDVYSSTLYVSEYELNSYMNDVCATFRKYAEMKRVRFVYES 915
KN +L+L +++F +I + V + +L + V FR AE K++ F S
Sbjct: 962 QKNAERMLRLMNQILDFRKIQNQKMKVLVEKTDLIPLLEKVMINFRLIAEEKKINFRLAS 1021
Query: 916 NFDYLNVWFDSDKMGSILKNILSNALKYTPENGSVCICACEEGNTWSIEVKDTGIGIPSS 975
+ W D DK I N++SNA KYTP ++ I ++ + +I V D GIGI +
Sbjct: 1022 ELKSIYAWIDRDKFEKIFFNLISNAFKYTPAEKAITIEVTKQTDKVTISVVDEGIGIEPT 1081
Query: 976 EQKKLFRNCFRGSNVVNLKVTGSGIGLMLVYKLVKLHKGKIHIQSVEHQGTCVQITFPKG 1035
+ + LF+ F N+ SGIGL LV ++V +H G I + S G+ +T P
Sbjct: 1082 KLRTLFQR-FETLAQQNMLQPSSGIGLSLVKEMVDMHHGTIKVTSEPEAGSRFIVTLPLQ 1140
Query: 1036 NTHLH---KAKFI-----SPKT-PNERMDAVVLGGTSDLPVLEAPQIKTSLQRILVVEDN 1086
+ +FI SP T P+ + D +E +L ILVVEDN
Sbjct: 1141 KEVFEQDSQVEFILNDSQSPTTHPDSSLQTEKRAEAEDKEDMENNTAPDTL-TILVVEDN 1199
Query: 1087 DDLRNYLVDMLMAGYNIQSCSNGKDALVIIKEFNPDLVISDIMMPEMSGDELCSAIKTSV 1146
++L+ +L ++L Y + + SNGK+ L + PDL+ISD+MMP M G E+ IK +
Sbjct: 1200 EELKAFLKNILSENYTVITASNGKEGLQHAVDNIPDLIISDVMMPVMDGLEMIRQIKENN 1259
Query: 1147 EMSHIPVILLTALGDEKNILGGLEIGADAYITKPFSVGILKVTIKNILANRELLRQVYNS 1206
+ HIP+I+L+A + + GLE G D YITKPFS LK I ++L R+ L+++Y +
Sbjct: 1260 NICHIPIIVLSAKASLDDRIAGLEQGIDDYITKPFSATYLKTRIASLLRQRKSLQEIYMA 1319
Query: 1207 IENKEKHLPVNCTNT--------LDWKFIASVKECIEKNMGDLDFGVDVLSNQHHMSRTS 1258
+ K + V T D +F+ V E IE+ M + + +D + +SRT
Sbjct: 1320 KLTEGKEIAVAEALTPSQPQITPYDEQFMQKVMEFIEEQMDNAELTIDEFAEHLMLSRTI 1379
Query: 1259 FYNKLKALTGYAPADYIRMIRLQRAAQLLKQKEYTITEIAEIVGFSDAKYFREVFKKYYN 1318
FY KLK++ G P D+IR +R++RAAQL+ EY +++A + GF+D KYF + FKK
Sbjct: 1380 FYRKLKSIIGLTPVDFIREVRIKRAAQLIDSGEYNFSQVAYMTGFNDPKYFSKCFKKVVG 1439
Query: 1319 VSPSKF 1324
++PS++
Sbjct: 1440 ITPSEY 1445
Score = 33.5 bits (75), Expect = 1e-04
Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 5/55 (9%)
Query: 18 ISSAVSKGQI-----YKYIGLEDGLNNQKIYHIQKDRRGYMWFLTQEGVDRYDGK 67
IS VSK + +K +DGL + + +Q+D++G +W L++ + ++D +
Sbjct: 658 ISQIVSKNLLSNKIEFKTYTTDDGLASDLVQAMQEDQQGNLWILSENAISKFDAQ 712