Pairwise Alignments
Query, 1330 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1511 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Score = 461 bits (1185), Expect = e-133
Identities = 394/1529 (25%), Positives = 683/1529 (44%), Gaps = 238/1529 (15%)
Query: 8 RKLLVFIVLLISSAVSKGQ---IYKYIGLEDGLNNQKIYHIQKDRRGYMWFLTQEGVDRY 64
+++L I+L +++ V + Q + + EDGL+ + + +D + +WF T +G++R+
Sbjct: 3 KRILYLILLCLTAPVVQAQQHSFFTHYSTEDGLSQNTVMSMLQDHKDNLWFATWDGINRF 62
Query: 65 DGKHIKHYTFSDDSMKLDSRIALNWLYMDQEDVLWVIGQKGRIFRYDSQHDKFE------ 118
DG + K Y + + + +Y D+ LW++ R+ R+D + + FE
Sbjct: 63 DGYNFKTYKARQGNYISLTNNRADRMYEDRYGFLWLLTYDNRVHRFDPKTETFEQVPAAG 122
Query: 119 --------------------LAYVHPELIR----------NKFQAFLDYGYLDKNDHIWL 148
L H IR K + L DH +
Sbjct: 123 EEGSTYNIHAIQVLPDGTVWLLTEHDGAIRVVTLPQKNYTTKSDIYSTKSGLFPADHFYQ 182
Query: 149 CYKDTI--TWYNIRTGTTQHMP---KPVDGAISTIEQADG---GHFFIGTGSGLFCVGIE 200
Y+D W G P +PV+ + T + DG + + C +
Sbjct: 183 VYQDKAGNHWLLTDNGLGMIRPGEQQPVNYFVETKGKQDGMNQAFYAVRECEDDICFASD 242
Query: 201 KGEL----KQIPDEVVKSIVTPVHELYYHTVSK-QLFVGSYKEGILIYDIGKTQKITPCY 255
+G + KQ + + + T HTVS V + +G + ++ KT K T Y
Sbjct: 243 RGRIWCYQKQGGEFRLLELPTKARITSIHTVSNGNTVVTTDSDGFFLCNL-KTNKHTH-Y 300
Query: 256 AP---NNVEVNQIVALNAD---ELLIATGGKGVYKLNVNTCKS---EPYITADYSSYNGM 306
+P + I++ D E+ GV ++ N + +YS N
Sbjct: 301 SPVTCKELSAQPILSAYVDRTSEVWFEQEEPGVV-VHFNPATGVVRREQMRVEYS--NAD 357
Query: 307 NGNNINDIYVDEEERIWLANYPTGITI----RNNRYGRYDLIKHSLGNNRSLVNDQVHDV 362
I+ D IW+ Y G + RN YD LG+N ++++H
Sbjct: 358 RSRPAFHIHEDVHGHIWVHPYGGGFSYFDRDRNCLVPFYD----DLGSNNWRFSNKIHAA 413
Query: 363 IEDSDGDLWFAT-SNGISFYQTDTREWCSF----FSSFDPVPDDENHI---FLALCEVSP 414
D G+LW T S G+ E +F FS PVP + + ++CE
Sbjct: 414 FSDKQGNLWLCTHSKGL--------EKVTFRNVPFSMLTPVPHEYESLSNEVRSVCEDKQ 465
Query: 415 GVIWAGGFTSGIYKIEKKKGFKISYLS---PAAIAGIRPDQYIYDIKKDSSGDVW----S 467
G +W G G+ ++ I +L+ ++ G + Y I +DS G +W
Sbjct: 466 GNLWV-GLKDGMIRLYDSNRKFIGHLTGNGTISMTGTPMEGTAYFIMQDSKGIIWIATKG 524
Query: 468 GGYYHLKRINLETKNVRLYP-----------GVSSITTILEKNARQMWIGTRMG--LYQL 514
G ++I+ + + +L +++ + E + ++W T G Y
Sbjct: 525 NGLVRAEQISPTSMSYKLTRYQHDSNDMYSLSDNNVYCVYEDHHGRIWAATFAGGINYIS 584
Query: 515 DKQSGVYRYID-------LPVESPYICALYQRE-DGILYIGTRGAGLLVYDINKKK---- 562
+ G +I+ P++ Y + +G L++GT G + +D N KK
Sbjct: 585 QGEHGETVFINHRNNLKGYPIDVCYKARFITSDNNGRLWVGTT-TGAVAFDENFKKPEDI 643
Query: 563 -FIHQYR--TDNCALISDNIYTIIPRQD-------------------------------- 587
F H R D +L +++++ II Q
Sbjct: 644 QFHHFSRVPNDTKSLSNNDVHWIIATQQKELYLATFGGGLNKLISISENGHGEFKSYSVL 703
Query: 588 ----------------ENLLMGTENGITIYSPKDHFFRNWTREQGLMSVNFNAGSATTYS 631
+NL + TENGI + P F N+ V F+ ++T S
Sbjct: 704 DGLSSDVLLSIREDHKQNLWISTENGICKFVPSGERFENYDERSISFRVRFSEAASTLTS 763
Query: 632 NSTLVFGGNDGAVKFPTDIEIPEPYYSRLLLRDFMIAYHPVYPGDDGSPLKKDINETDCL 691
++FG ++G F D Y ++ M+A V PG+ S LK D+++T L
Sbjct: 764 GGDMLFGTSNGLFMFTPDSIRKSSYVPPVVFSKLMVANEDVIPGEK-SILKVDLDDTQEL 822
Query: 692 ELAYGQNTFSLDVASINYDYPSNILYSWKIDGYHKEWTRPSQDNRIVVRNLPPGSYTLQI 751
L++ +N FS+ A+++Y P NI Y++ +DG+ K+WT + + NLP G Y ++
Sbjct: 823 VLSHDENIFSVQYAALDYTNPQNIQYAYILDGFEKQWTFADRQRSVTYTNLPKGDYIFRV 882
Query: 752 RTVSNEEKYKTYETRSIQIIITPPVWASMWAMVGYAILVVLIMI----IIFRVIMLHK-- 805
R+ +++ + E R + I I P W + A V Y V+LI+ I+F + L
Sbjct: 883 RSTNSDGVWVDNE-RILNITILPSFWETPLAYVLYVCFVLLIIFVAVYILFTIYRLKHEV 941
Query: 806 --QKKISDEKTRFFINTAHDIRTPLTLIKAPLEEVVENHMVAEKALPHMNMALKNVNTLL 863
+++ISD K RFF N +H++RTPLTLI P+E+V++N + A + + +N N +L
Sbjct: 942 SVEQQISDIKLRFFTNISHELRTPLTLIAGPVEQVLKNDKLPADAREQLVVVERNTNRML 1001
Query: 864 QLTTNLINFERIDVYSSTLYVSEYELNSYMNDVCATFRKYAEMKRVRFVYESNFDYLNVW 923
+L +++F +I + V + + +++ + F AE + F++++ + LN+W
Sbjct: 1002 RLVNQILDFRKIQNKKMKMQVQQLNVVAFVRKIMDNFESVAEEHNIDFLFQTEKEALNLW 1061
Query: 924 FDSDKMGSILKNILSNALKYTPENGSVCICACEEGNTWSIEVKDTGIGIPSSEQKKLFRN 983
D+DK I+ N+LSNA KYTP + + E+ T S+ V+D GIGI +++K LF
Sbjct: 1062 VDADKFEKIVFNLLSNAFKYTPNGKMITVFIREDEGTVSVGVQDQGIGIAENKRKSLF-- 1119
Query: 984 CFRGSNVVNLKV---TGSGIGLMLVYKLVKLHKGKIHIQSVEHQGTCVQITFPKGNTHLH 1040
R N+V+ + SGIGL LV +LV++HK I + S +G+C ++ F KG H +
Sbjct: 1120 -VRFENLVDKNIFNQASSGIGLSLVKELVEMHKATISVDSRLGEGSCFKVDFLKGKEHYN 1178
Query: 1041 KA------KFISPKTPNERMDAV-----VLGGTSDLPVLEAPQIK------TSLQRILVV 1083
+ ++P + +D +D P LE +K +S + +L+V
Sbjct: 1179 SSVEFILEDSVAPLSMERIVDIANSSLQTEAAIADAPDLEVSAVKEEAEESSSKELMLLV 1238
Query: 1084 EDNDDLRNYLVDMLMAGYNIQSCSNGKDALVIIKEFNPDLVISDIMMPEMSGDELCSAIK 1143
EDN +LR++L + + Y + S G + ++ PD++ISD+MMPE G E+ ++
Sbjct: 1239 EDNQELRSFLRSIFASTYRVVEASEGMEGWSKALKYLPDIIISDVMMPEKDGIEMTRELR 1298
Query: 1144 TSVEMSHIPVILLTALGDEKNILGGLEIGADAYITKPFSVGILKVTIKNILANRELLRQV 1203
+ SHIP+ILLTA ++ L GLE GAD YITKPFS L+ ++N+L R+ L+
Sbjct: 1299 ADMTTSHIPIILLTAKTTIESKLEGLEYGADDYITKPFSATYLQARVENLLMQRKKLQNF 1358
Query: 1204 YN----------------------------SIENKEKHLPVNCTNTLDWKFIASVKECIE 1235
Y S +E +P N D KF+ + + +E
Sbjct: 1359 YRDSLTHVTVSETPVAQGETLAGHASAEPVSSAAEEPAMPEMSPN--DRKFMDKLVDLME 1416
Query: 1236 KNMGDLDFGVDVLSNQHHMSRTSFYNKLKALTGYAPADYIRMIRLQRAAQLLKQKEYTIT 1295
+NM + + VD L + +SR+ F+ KLK LTG AP ++I+ +R++RAAQL++ E+ +T
Sbjct: 1417 QNMDNGELVVDDLVRELAVSRSVFFKKLKTLTGLAPIEFIKEMRIKRAAQLIETGEFNMT 1476
Query: 1296 EIAEIVGFSDAKYFREVFKKYYNVSPSKF 1324
+I+ +VG +D +YF + FK ++P+++
Sbjct: 1477 QISYMVGINDPRYFSKCFKAQVGMTPTEY 1505