Pairwise Alignments
Query, 1326 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1392 a.a., response regulator receiver domain protein from Bacteroides ovatus ATCC 8483
Score = 542 bits (1396), Expect = e-158
Identities = 410/1409 (29%), Positives = 657/1409 (46%), Gaps = 164/1409 (11%)
Query: 47 ILQDKQGFMWFGTKDGLDRYDGISFRAFMKE---SGTLGNNFITSLYEDQQGQIWIGT-D 102
++QD +GFMW GT +GL+RY+G F E S L ++ I + ED+ G IWI T
Sbjct: 1 MMQDSRGFMWMGTINGLNRYNGKEFVVVHPELPGSSLLPDSRIRYMVEDKNGFIWIRTFS 60
Query: 103 VGLYVYSPEHETVERFIMKSDLDTGIDYTVNLVTGDKDGGIWVVTQSQAVFYYN------ 156
L+ Y P E+ I + +T V + D +W V Y N
Sbjct: 61 NTLFCYDP---GTEKMIDYDPQNKAKIFTQIEVFSNGDVWMWGNRGCCRVRYVNGKMEVW 117
Query: 157 -PQTNKL----INYL-SDQSGRLKFGSLGQLYFDSD--------NVCWLDIRDGN----- 197
P+ KL I+++ D ++ G+ +L+ +D V +L+ ++G+
Sbjct: 118 KPEDEKLRSQKISFVFEDSEHKVWIGAHEELFRIADGKVDSMLKGVTFLNAQEGSDLYFI 177
Query: 198 -----LYFSKDKLQTLVPVFPKDGNEPFKGEYICKLLPGPYNCMYVGTITGLKEVNLTNK 252
+ F + +L + PV D P L G + + T + TNK
Sbjct: 178 GGGGIVIFDRARL-SFSPVIYYDKENPTAHSRSYMLNEG---ILMIATNEKTYTFD-TNK 232
Query: 253 TVRTLLSKDESGDDIYVREIAFYSDDELWAGTESGLYIYNLRTKKTVH-LRNVSGDPYSI 311
V +K G+D+ + + ++W SG ++ R T L + D S+
Sbjct: 233 RVWIPSAKFFQGNDLRNANFSVDNKGDVWVYNMSGT-LWRHRPGNTFEPLHLIPSDILSL 291
Query: 312 SDNAIYSICKDREGGIWI------------------------------------------ 329
Y I D IWI
Sbjct: 292 ISQERYQIYHDSRNIIWITTFGNGLFAIDENNGKTFHYTADKDLTTNYLLCVTEDRSGEI 351
Query: 330 --GSYFGGVNYYPKQYTYFDKVYPRTEID-EMGKRVREFCADHDGTLWIGTEDKGLFHYY 386
G+ GG++ FD YP + + VR D DG W GT D G H
Sbjct: 352 WVGTELGGISKISLTNYPFDIFYPSPGGNADRDNAVRLIYEDEDGRYWFGTRD-GNLHVC 410
Query: 387 PSTGLIEPFRHPDIYHNVHGLCLDG-----------NYLWVGHFAKGLNRIDLRTHAV-- 433
ST ++ L ++G Y W+G GL + + A+
Sbjct: 411 DST-----------LRQIYDLRIEGGLPFSIAEDTLGYKWLGTKGGGLVLLSPKGDAIVE 459
Query: 434 KHYFD-------APNDIFSICRTTSGNLWLGTTAG---LFRYHSETNRFER--VPELGWV 481
KH D + N+IF+I R +W+ T G L H F +
Sbjct: 460 KHTLDDWVWQSSSSNNIFTIMRDNKDRMWIATFGGGLHLGERHQGKLTFRQFVTENKHQC 519
Query: 482 FIYNIKEDKQGNLWLATYIDG--VYKRNVRTGEWEHY----MHDETNPSSLPSNKVLSIF 535
+ + +D+ G +W+ T DG V+ + + Y +H E + SL N+V +F
Sbjct: 520 MMRAMIQDRTGLIWVGTN-DGVIVFHPDELIQDKNKYISLHLHKE-DQQSLSHNEVKVVF 577
Query: 536 EDSQNQLWFTTQGGGFCRFDPSGKI----FVRYDSSIGLPSNVVHRIEEDEKGLFWITTN 591
EDS+ +W T GGG ++ F Y++ GL + V I ED +G W++T
Sbjct: 578 EDSKGNIWLGTTGGGLNLLVREKQLEKSWFKHYNADNGLANETVQAILEDNEGYIWVSTE 637
Query: 592 KGLVHFNPKTLEFKVYTIANGLLSNQFNYQSSYKDKNGRIYFGSINGFISFEPSVFVDND 651
G+ FN +T F+ + +N + FN S +K KNG + FGS NG F PS +
Sbjct: 638 SGISKFNLQTERFENFIFSNNRHAAIFNELSCWKKKNGELMFGSYNGVYIFNPSGIKFDT 697
Query: 652 FLPPVVITDFMLFNKKVPVGSTDSPLKQSITLSDYLELQSNQNSFSFSVAALSYQSPDMN 711
+ P V++T + + DSPL +SIT + + L+ NQNSF+ L++ + ++N
Sbjct: 698 YAPRVLVTGLWINGNPMRPQGQDSPLMESITNTKKIVLEHNQNSFNLECTMLNFHAAELN 757
Query: 712 TVLYKLEGYDSEW-YSVGKNLITYSNLPYGTYVLKVKAANSDGIWNPDVRTLKIRILPPF 770
Y LEG++ +W N+ TY N+P G Y+ KVK NS G+W+ + TL++ ILPP+
Sbjct: 758 QYAYYLEGFEKDWNLGSRNNMATYRNVPPGRYMFKVKGCNSFGVWSSEETTLEVIILPPW 817
Query: 771 YLSVWAYIIYVILILGALFATFFYFRKRAVEKHQRAMEKFEQEKERELYTSKIEFFTNVA 830
+ S W ++ IL+ G L YF R K R E EK+ Y K+ FFTN++
Sbjct: 818 WKS-WIAVLLYILVGGIL----IYFAVRLALKMHRLNMAVEVEKQLTEY--KLRFFTNIS 870
Query: 831 HEIRTPLTLIKSPLESVLTEKELPENVKMELEIMDQNAERLLNLTNQLLDFRKTENKGFK 890
HE RTPLT+I+ +E + +K+LP +L ++ +++ RLL L +QLL+FR+ +N +
Sbjct: 871 HEFRTPLTIIRGAIEDLSNQKDLPPAANKQLGLLTKSSNRLLRLIDQLLEFRRLQNNKME 930
Query: 891 LNPVECSVGSIIRSVYKRFTTLVNQKGIELKVEIPEEELLASVDKEALTKILSNLFTNAL 950
L E +Y F + +K IE E + +D+ + KI NL +NA
Sbjct: 931 LKLEETVAERFFYDIYLTFKDMAAKKRIEYLFESNDSTGRMLLDRSKMDKIAYNLLSNAF 990
Query: 951 KYAQTYAYLSLSVDEAGKE--FTIVMSNDGKIIPIEMRENIFRPFVQYRDGKDIVPGTGI 1008
K + + +D + + FT+ +S+ G +P E R+ +F F Q D GTG+
Sbjct: 991 KNTPAGGKIVMRLDSSAENDTFTLSVSDSGPGVPAEKRKMLFVRFEQINYASD---GTGV 1047
Query: 1009 GLALARSLAELHQGTLT-MDQDMECNRFILSIPI--RHQTASDVLEEEHREKPVYDEEDN 1065
GL L LA++H+G + D + F L+IP+ ++ +D+++ E V +E
Sbjct: 1048 GLHLTAELAKVHKGNVAYSDSSLGGACFSLTIPLSDKNYDPADIVQSSASEPDVAVKEIT 1107
Query: 1066 ETRIMPSDKDKKEVAS----------VLIVEDNKDMLAFVARQLSPLYHVITAENGIEAL 1115
+P +K + + + V++++D+ D+ + QL + V TA NG E L
Sbjct: 1108 TGATLPDEKAVEILGTSVNKPFKEYKVMVIDDDDDVRTLIESQLGKYFTVSTASNGAEGL 1167
Query: 1116 KVLEHEYINLVISDIMMPEMDGLELCEHLKSNLDYSHIPIILLTAKTTLESKIEGLEQGA 1175
+ L + ++V+ D+MMPEMDG E + LK++ + SHIP+ILLTA ++ E +++G++ GA
Sbjct: 1168 EKLAEDQPDIVVCDVMMPEMDGFEFTKRLKNDFNISHIPVILLTAYSSEEHQLKGIQLGA 1227
Query: 1176 DAYIEKPFSVEYLRVNVANLLSNRERLRRRFIESPFIKADTMAQTKADEVFIQKLNEYVS 1235
D+YI KPFSV+YL V L+ RE+L+R+F P ++ T D++F+ K+N +
Sbjct: 1228 DSYITKPFSVQYLLARVVKLIEQREKLQRKFATEPGNLQPLISTTDRDKIFLDKINAIIE 1287
Query: 1236 QHLDNTDLVIDDMAEAMNMGRSNFYRKLKGVLDMSPNEYLRLIRLKKAAQLLKDGRYGIV 1295
+++ + + +D A A+ +GR+ FY KLK ++ SPNEY+RL+R+K+AA+LL I
Sbjct: 1288 RNMGDAEFKLDTYAPALGLGRTTFYSKLKSIVGCSPNEYVRLLRMKRAAELLITSDINIS 1347
Query: 1296 EISYMVGFNSPSYFSNCFKKQFGVLPKDF 1324
E Y VG N P YFS CFK FG P +
Sbjct: 1348 EAGYQVGINDPFYFSKCFKNTFGKSPSQY 1376
Score = 72.0 bits (175), Expect = 4e-16
Identities = 85/391 (21%), Positives = 162/391 (41%), Gaps = 30/391 (7%)
Query: 34 DINNGLSQNTVHAILQDKQGFMWFGT-KDGLDRYDGISFRAFMKESGT-LGNNFITSLYE 91
DI + +SQ + I D + +W T +GL D + + F + L N++ + E
Sbjct: 287 DILSLISQER-YQIYHDSRNIIWITTFGNGLFAIDENNGKTFHYTADKDLTTNYLLCVTE 345
Query: 92 DQQGQIWIGTDV-GLYVYSPEHETVERFIMKSDLDTGIDYTVNLVTGDKDGGIWVVTQSQ 150
D+ G+IW+GT++ G+ S + + F + D V L+ D+DG W T+
Sbjct: 346 DRSGEIWVGTELGGISKISLTNYPFDIFYPSPGGNADRDNAVRLIYEDEDGRYWFGTRDG 405
Query: 151 AVFYYNPQTNKLINYLSDQSGRLKFGSLGQLYFDSDNVCWLDIRDGNLYFSKDKLQTLVP 210
+ + ++ + R++ G + D+ WL + G L K +V
Sbjct: 406 NLHVCDSTLRQIYDL------RIEGGLPFSIAEDTLGYKWLGTKGGGLVLLSPKGDAIVE 459
Query: 211 VFPKDG--NEPFKGEYICKLLPGPYNCMYVGTITG---LKEVNLTNKTVRTLLSKDESGD 265
D + I ++ + M++ T G L E + T R ++ E+
Sbjct: 460 KHTLDDWVWQSSSSNNIFTIMRDNKDRMWIATFGGGLHLGERHQGKLTFRQFVT--ENKH 517
Query: 266 DIYVREIAFYSDDELWAGTESGLYIYN----LRTK-KTVHLRNVSGDPYSISDNAIYSIC 320
+R + +W GT G+ +++ ++ K K + L D S+S N + +
Sbjct: 518 QCMMRAMIQDRTGLIWVGTNDGVIVFHPDELIQDKNKYISLHLHKEDQQSLSHNEVKVVF 577
Query: 321 KDREGGIWIGSYFGGVNYYPKQYTYFDKVYPRTEIDE--MGKRVREFCADHDGTLWIGTE 378
+D +G IW+G+ GG+N ++ + D + V+ D++G +W+ TE
Sbjct: 578 EDSKGNIWLGTTGGGLNLLVREKQLEKSWFKHYNADNGLANETVQAILEDNEGYIWVSTE 637
Query: 379 DKGLFHYYPSTGLIEPF-----RHPDIYHNV 404
G+ + T E F RH I++ +
Sbjct: 638 -SGISKFNLQTERFENFIFSNNRHAAIFNEL 667
Score = 53.9 bits (128), Expect = 1e-10
Identities = 41/162 (25%), Positives = 70/162 (43%), Gaps = 11/162 (6%)
Query: 12 VFIFHTFYVFADLNEGYAFR-SLDINNGLSQNTVHAILQDKQGFMWFGTKDG----LDRY 66
V +FH + D N+ + + LS N V + +D +G +W GT G L R
Sbjct: 540 VIVFHPDELIQDKNKYISLHLHKEDQQSLSHNEVKVVFEDSKGNIWLGTTGGGLNLLVRE 599
Query: 67 DGIS---FRAFMKESGTLGNNFITSLYEDQQGQIWIGTDVGLYVYSPEHETVERFIMKSD 123
+ F+ + ++G L N + ++ ED +G IW+ T+ G+ ++ + E E FI ++
Sbjct: 600 KQLEKSWFKHYNADNG-LANETVQAILEDNEGYIWVSTESGISKFNLQTERFENFIFSNN 658
Query: 124 LDTGIDYTVNLVTGDKDGGIWVVTQSQAVFYYNPQTNKLINY 165
I L K G + V+ +NP K Y
Sbjct: 659 RHAAI--FNELSCWKKKNGELMFGSYNGVYIFNPSGIKFDTY 698