Pairwise Alignments
Query, 1420 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Subject, 1433 a.a., two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) from Bacteroides thetaiotaomicron VPI-5482
Score = 470 bits (1210), Expect = e-136
Identities = 388/1493 (25%), Positives = 680/1493 (45%), Gaps = 217/1493 (14%)
Query: 39 NEGLPHNFIDDLYKDSRGFMWISTAGGGLSRYDGYEFVNYTPN-NHQCKLKSNFIRNVCE 97
++GLP+N + LY+DS+GF+W++T GLSRYDG F+ + P + L N I ++ E
Sbjct: 34 SDGLPNNSVRYLYQDSKGFLWLATL-NGLSRYDGNSFLTFRPEIGDKVSLADNRIYDLTE 92
Query: 98 DAFQRLWIVSEGGTDIIDLSTLKPIIPHDPKGILPKILELPATRIMKDTQGCIWL-HCDN 156
D LWI + ++ L+ D G LE + I G +WL H N
Sbjct: 93 DKNGFLWISTT--PELFSCYDLQRACFVDYTG--TGALEKNYSSIFVAANGDVWLRHSGN 148
Query: 157 ALHRIEFNDKGEVQILSTLSPVYLNGPDIALKDIDED--GKIWMGNNGEIRKVALSPQKR 214
R+ + K + + N PD ++ ++ED G+IW+G + V+ K
Sbjct: 149 GCLRM-VHQKDRQMVSTEFKTERGNLPDNRVQFVNEDAGGRIWIGTQRGLVSVSDGQYK- 206
Query: 215 LVTTPIADCLKFEAGTYISDFLSKENEVWISSDRGLFRYNKTGNVIKRYEHDS--GNPYS 272
+ D L + S K + ++++D ++ Y T + + S S
Sbjct: 207 -----VEDRLLH----FTSSLAFKNDMYFLTADGDIYCYQTTKQKLTKVGSLSAVAGKTS 257
Query: 273 LSQNYLTNLAITDDKQLIVA---------TLRGINIYNPMTDNFERIACD---------- 313
+ N+L N DK +I+ R I++ + + + CD
Sbjct: 258 PTGNFLLN-----DKWVILTNTGVFNYDFNTRKISVDSGLNIRNGEVICDNHGDFWIYNH 312
Query: 314 -------------------LPNGGTNLLNSNFINCILTDGEHIWFGTETGGINLLNPRQL 354
+P ++ + + IW T G+ + +
Sbjct: 313 TGCVTYILAKNGARKEFQLIPEDKLGYIDYERYHIVHDSRGIIWISTYGNGLFAYDTTED 372
Query: 355 SIRSYRHDKENPSSLSYNPVNAIYEDVYGTLWVGTVEGGLNRKERNSEDFTHYTREHGGL 414
+ + + + S +S + + + ED G +WV + GL+R +E + E L
Sbjct: 373 KLEHFLANINDQSHISSDFLLYVMEDRAGGIWVSSEYSGLSRISVLNEGTSRIYPESREL 432
Query: 415 --SHNSVSALTADTDNHLWIGTWGGGLNLLDLKAPRQILEVISSQTGGGFPINFIGVLNY 472
N++ LT D +W+GT GGL D + S + F N +
Sbjct: 433 FDRSNTIRMLTKMPDGDIWVGTRKGGLYTFD-------SNLHSKMSNQYFHSNIYAIAE- 484
Query: 473 DPINEG-IWIGA-NQGLYFYDP-VKKEITAPLPDKAAENIHGCIGSIIDKEGKLWVGCLE 529
N+G +W+G GL D + E++ D A+ + + D++ ++W+G
Sbjct: 485 --DNQGEMWVGTRGNGLKIGDSWYRNEVS----DPASLSENNVFSLFRDRKDRMWIGTFG 538
Query: 530 GVYIIDLHSRSSKGEFQYRH-LNYKLDDPSSRLIE------------------------- 563
G ++L ++ G++++RH L K R+IE
Sbjct: 539 GG--LELAEPTTDGKYKFRHFLQQKFGLRMVRVIEEDDNGMIWVGTSEGVCIFHPDSLIA 596
Query: 564 ------------------KITCFYQGKDGTLWLGSNGYGI-YQRKIDAQGKEQFISYSTA 604
+I C Y+ G +W+G++G G+ D ++ Y T+
Sbjct: 597 DSDDYHLFNYTNGTFCSNEIRCIYRDTKGRMWVGTSGSGLNLCEPEDNYRSLKYEHYGTS 656
Query: 605 QGLPNNSVRGILEDNNGNLWISTNNGLSCYHQAENRFINYTIQDGLIDTQFYWNASCGSS 664
+GL N+ ++ IL DNNGNLW++T G+S ++ + F NY + + N++C
Sbjct: 657 EGLVNDVIQSILGDNNGNLWVATEYGISKFNPTNHSFENYFFSSYTLGNVYSENSACVGV 716
Query: 665 HDLLYFGSVGGLVAIESNRPAMSLPAAKVRFTRLRIGNEEILP--GSEYLSEDIAITTEL 722
L FG+ GL+ I+ ++ S + V FT L + +I P G L + +A + E+
Sbjct: 717 DGKLLFGTNYGLLVIDPDKIQDSETFSPVVFTDLHVNGTQINPTMGDSPLKQSLAYSDEI 776
Query: 723 KLHEKEKSFSLEFAALNFESNNTAIYSYRLVGFDDKWVQVPGNRRFASYTNLPPGSYTLQ 782
L + SF ++F+ ++ + Y Y L +D W P FAS+ L PG+Y L
Sbjct: 777 TLKYFQNSFLIDFSTFDYSDSGRTKYMYWLENYDKGW-STPSPLNFASFKYLNPGTYVLH 835
Query: 783 VRYTPDGENEGENITELKITIVPYFYKTVWFILFIIVLLSVSVWQFYQWRI-RNLKRQKE 841
V+ E+ T LKI IVP F+KT W +L ++LL V++ ++ +RI RN
Sbjct: 836 VKSCNGAGVWNESETTLKIVIVPPFWKTNWAMLGYVLLLIVTL--YFTFRIVRNFN---- 889
Query: 842 YLHRTVEERTHELEQQKHLLENQTDELSRQNQMLIQQNEKITRQKAQLIRMSRKVQELTL 901
S +N++ ++ ++LT
Sbjct: 890 ---------------------------SLRNRINVE-------------------KQLTE 903
Query: 902 DKISFFTNITHEFRTPITLIIGPIERALKLSYNPQ-VIEQLNFVERNSKYLLSLVNQLMD 960
K+ FFTNI+HEFRTP+TLI G +E+ +++ P+ +I L ++++++ +L L+NQL++
Sbjct: 904 YKLVFFTNISHEFRTPLTLIQGALEKIQRVADIPRDLIHPLKTMDKSTQRMLRLINQLLE 963
Query: 961 FRKVESGKLEIVKTRGNFLKFIDSLITPFEVFAQERNIVLKRYYRMEMPEILYDEEAMRK 1020
FRK+++ KL + + + F+ + F A+++N+ + + ++ D+ + K
Sbjct: 964 FRKMQNNKLALSLEETDVIAFLYEIFLSFGDVAEQKNMNFRFIPSIPSYKMFLDKGNLDK 1023
Query: 1021 VVTNLLSNAIKFTPNGGTVSLYLSALFAKDSEKETLYICVKDSGSGIPEEDLNRIFNRFY 1080
V NLLSNA K+TP+ GT+ L ++ D K+TL I V D+G GIP+E N +F RF
Sbjct: 1024 VTYNLLSNAFKYTPSNGTIILSVTV----DEVKKTLQIQVADTGVGIPKEKQNELFKRFM 1079
Query: 1081 QSQNQVKYPVYGQAGTGIGLYLCKRIVQMHGGEIKAFNNRHAGCSFRILLPLQRNERKDE 1140
QS + G+GL+L +VQ+H G I+ +N G F + +P ++ E
Sbjct: 1080 QSS-------FSGDSIGVGLHLSYELVQVHKGTIEYKDNDGGGSVFTVCIPTDKSV-YSE 1131
Query: 1141 KTIIIDHN-------DSSATPVQDSGSPKEKEALS-------ILVVEDNADMRGYIRSIL 1186
K +I N + ++ S E E ++ +L++ED+ D+R +++ +
Sbjct: 1132 KDFLIPGNVLLKEAGGQAHHLLELSEELPEPEKIAEPLNKRKVLIIEDDNDIREFLKEEV 1191
Query: 1187 REQYHVLEAANGEEALHILNSNPIDFIISDLMMPVMDGIELSRRVKETFAISHIPFLMLT 1246
+ V AA+G + D II D++MP M G E+++++K FA SHIP ++LT
Sbjct: 1192 GVYFEVEVAADGTSGFEKARTYDADLIICDVLMPGMTGFEVTKKLKSDFATSHIPIILLT 1251
Query: 1247 AKTSQEARLESYRMGVDEYLLKPFDETLLLARIQNILENRKRYQRKFTLDMDVDVLNMEE 1306
A S E LE G D Y+ KPF LLLAR+ ++E R + + KF+ + + +
Sbjct: 1252 ALNSPEKHLEGIEAGADAYIAKPFSIKLLLARVFRLIEQRDKLREKFSSEPGIVRAAVCS 1311
Query: 1307 ESGDKKFLNQVMEVIKENYKNSYFEVSDFCEAVGVSKSLLNKKLQNLIGQSAGQFIRNYR 1366
DK+F +++ V+++N F + +F + + + +++ +KL+ + G S +++R R
Sbjct: 1312 TDRDKEFADRLAVVLEQNLSRPEFSIDEFAQLMKLGRTVFYRKLRGVTGYSPNEYLRVVR 1371
Query: 1367 LNIARELILKNRETKNMNIAEVAYEVGFNDPKYFTRCFTKHFNVTPSALLNNE 1419
+ A EL+L +N+ +AEVAY+VG +DP YF++CF F V PS E
Sbjct: 1372 MKKAAELLLSG---ENLTVAEVAYKVGISDPFYFSKCFKTQFGVAPSVYQRGE 1421
Score = 45.1 bits (105), Expect = 5e-08
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 6/58 (10%)
Query: 603 TAQGLPNNSVRGILEDNNGNLWISTNNGLSCYHQAENRFINYTIQDG----LIDTQFY 656
T+ GLPNNSVR + +D+ G LW++T NGLS Y N F+ + + G L D + Y
Sbjct: 33 TSDGLPNNSVRYLYQDSKGFLWLATLNGLSRYD--GNSFLTFRPEIGDKVSLADNRIY 88
Score = 40.4 bits (93), Expect = 1e-06
Identities = 60/283 (21%), Positives = 106/283 (37%), Gaps = 55/283 (19%)
Query: 26 RFADRYNITYVTMNEGLPHNFIDDLYKDSRGFMWISTAGGGLS----RYDG-YEFVNYTP 80
+ D + V+ L N + L++D + MWI T GGGL DG Y+F ++
Sbjct: 500 KIGDSWYRNEVSDPASLSENNVFSLFRDRKDRMWIGTFGGGLELAEPTTDGKYKFRHFL- 558
Query: 81 NNHQCKLKSNFIRNVCEDAFQRLWIVSEGGTDIIDLSTLKPIIPHDPKGILPKILELPAT 140
Q K +R + ED +W+ + G I +L I +
Sbjct: 559 ---QQKFGLRMVRVIEEDDNGMIWVGTSEGVCIFHPDSL--------------IADSDDY 601
Query: 141 RIMKDTQGCIWLHCDNALHRIEFNDKGEVQILSTLSPVYLNGPDIALKDIDEDGKIWMGN 200
+ T G C N + I + KG + + ++ S + L P+ N
Sbjct: 602 HLFNYTNGTF---CSNEIRCIYRDTKGRMWVGTSGSGLNLCEPE--------------DN 644
Query: 201 NGEIRKVALSPQKRLVTTPIADCLKFEAGTYISDFLSKENEVWISSDRGLFRYNKTGNVI 260
++ + LV I L G +W++++ G+ ++N T +
Sbjct: 645 YRSLKYEHYGTSEGLVNDVIQSILGDNNG-----------NLWVATEYGISKFNPTNHSF 693
Query: 261 KRYEHDSGNPYSLSQNYLTNLA-ITDDKQLIVATLRGINIYNP 302
+ Y S Y+L Y N A + D +L+ T G+ + +P
Sbjct: 694 ENYFFSS---YTLGNVYSENSACVGVDGKLLFGTNYGLLVIDP 733