Pairwise Alignments
Query, 1048 a.a., exonuclease, dsDNA, ATP-dependent from Escherichia coli BL21
Subject, 1171 a.a., chromosome segregation protein SMC from Ralstonia sp. UNC404CL21Col
Score = 84.0 bits (206), Expect = 6e-20
Identities = 207/927 (22%), Positives = 349/927 (37%), Gaps = 145/927 (15%)
Query: 32 LFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLM----TRDTAECLAEVEFEV 87
L I GP G GK+ ++DA+ L E+ +S D++ T+ A VE
Sbjct: 26 LVGIVGPNGCGKSNIIDAVRWVL-GESRAAELRGESMQDVIFNGSTQRKPAGRASVELVF 84
Query: 88 KGEAYRAF--WSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYG 145
RA WSQ + V RV + ++ + ++ G G
Sbjct: 85 DNAEGRAAGQWSQY-------AEVAVKRVLSRDGTSSYFINNQAVRRRDIQDIFLGTGLG 137
Query: 146 RFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQA 205
+ ++ QG + + AKP + LEE G Y K R E E +
Sbjct: 138 PRAYA-IIGQGMISRIIEAKPDDMRIFLEEAAGVSKY-----------KERRRETENRLS 185
Query: 206 QASGVALLTPEQVQSLTASLQVLTDEEK-----QLLTAQQQEQQSLNWLTRLDELQQEAS 260
+ ++ L ++L+ L + + Q L A +E+Q L WL R E Q E
Sbjct: 186 DTRENLTRVEDILRELGSNLEKLEGQAEVAQRFQALQADGEEKQHLLWLLRKREAQAEQE 245
Query: 261 RRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSA--ALAHTRQQIEEVNT 318
R Q+A++QA + E QL + + + A H+A AL ++ +
Sbjct: 246 RHQRAIEQAQIDLEAQTAQLRHIEAELETMRVAHYASSDAMHAAQGALYEANSEVSRLEA 305
Query: 319 RLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSD 378
++ + R I+ A +A QQ+Q Q + ELA + +Q D
Sbjct: 306 EIRYVVESRNRIQQQIATLTA---QQEQWHTQGEQAQEDLAAAEEELAMAEERAAQAAED 362
Query: 379 ----REHLRQWQQQLTHAEQKLNALAAITL------------TLTADEVATALAQHAEQ- 421
+ L + Q A+ LN A L AD+ L Q E+
Sbjct: 363 VARKADELPAMEAQWRDAQTALNDQRAAILQSEQALKLEAAHQRNADQALLQLEQRRERL 422
Query: 422 --------RPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEK 473
+P L L ++ Q++ LA+ Q A+++ + Q L+E R+ +++
Sbjct: 423 TQESSGLDKPDDVQLETLRAELAEQEEVLAEAQAALEDAETQVPQ----LDEARRAAQDR 478
Query: 474 TQQLADVKTICEQEARIKTLEAQRAQLQAG---QPCPLCGSTSH-----PAVEAYQALEP 525
Q ++ I EAR+ L+ + +Q QP S ++ Q EP
Sbjct: 479 VQ--SEAAAIASLEARLAALKQLQENVQTDGKVQPWLAKHELSELPRFWKKLQIEQGWEP 536
Query: 526 ---GVNQSRLLALE----NEVKKLGEEGATLRGQLDAITKQLQRDENEA--QSLRQDEQA 576
V + +L ALE + +K + + A + E A + L Q
Sbjct: 537 ALEAVLREKLGALEVSNLDWIKAFAADAPPAKLAFYAPPPAARPVEAPAGLRPLMSLVQV 596
Query: 577 LTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQ------------ 624
+AV + DD+Q L A+ + Q L G+
Sbjct: 597 TEPGMRAVLQDWLADVYIADDMQAALAARQTLPEGGTFVVQAGHLIGRSSVQLYAPDSEQ 656
Query: 625 --IAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQN 682
+ A Q+I +Q+ R Q+LL DE +S A R + A S Q
Sbjct: 657 AGMLARAQEIENLNKQV--RAQMLLA------------DEAKS-AAVRAEAAYS--QASQ 699
Query: 683 ELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWR--QVHEQCLALHSQQQTLQQQD 740
LT ++ R +Q T + L Q D L + + N R Q+ + + +Q +++Q
Sbjct: 700 NLTQVRARAEQATRRVHVL-QMDVL-KLSQAMERYNARSGQIDSELEEIRAQ---IEEQR 754
Query: 741 VLAAQSLQKAQAQFDTAL---QASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQ 797
+ A+S + Q D AL QA D QQAF E +L + L +Q R AQ
Sbjct: 755 AIRAES-EATFEQHDAALADMQARFEDSQQAF------EALEVRLSDARNALRDQERGAQ 807
Query: 798 -------TLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIR 850
L + AE L ++ Q D + +T+E + EL + + E T G ++
Sbjct: 808 EAHFAERNLQNRIAE-LKRNIQVASDQAQQIVLTLENARAEL----ETINEQTAHTG-LQ 861
Query: 851 QQLKQDADNRQQQQTLMQQIAQMTQQV 877
+ L++ A+ ++ ++ +T Q+
Sbjct: 862 EALERRAEKEEKLGLARMELDALTAQL 888
Score = 42.4 bits (98), Expect = 2e-07
Identities = 202/932 (21%), Positives = 343/932 (36%), Gaps = 116/932 (12%)
Query: 64 VSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARC-ADG 122
+ Q+Q DL + E E E A+ ++ + A + G L E++R A+
Sbjct: 251 IEQAQIDLEAQTAQLRHIEAELETMRVAH---YASSDAMHAAQGALYEANSEVSRLEAEI 307
Query: 123 KILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLN-AKPKERAELLEELTGTEI 181
+ + + + ATLT T+ + AA A +ERA E +
Sbjct: 308 RYVVESRNRIQQQIATLTAQQEQWHTQGEQAQEDLAAAEEELAMAEERAAQAAEDVARKA 367
Query: 182 YGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTASLQVLTDEEK-QLLTAQQ 240
++ AM Q + A+T L +A A+L EQ L A+ Q D+ QL ++
Sbjct: 368 -DELPAME-AQWRDAQTALNDQRA-----AILQSEQALKLEAAHQRNADQALLQLEQRRE 420
Query: 241 QEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIA 300
+ Q + L + D++Q E R + A Q+ + E +A + A + Q R +R+
Sbjct: 421 RLTQESSGLDKPDDVQLETLRAELAEQEEVLAEAQAALEDAETQVPQLDEARRAAQDRVQ 480
Query: 301 EHSAALAHTRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQ 360
+AA+A L++ +A A KQ E Q + WL +H+
Sbjct: 481 SEAAAIAS-----------LEARLA--------ALKQLQENVQTDGKVQPWLAKHEL--- 518
Query: 361 WNNELAG-WRAQFSQQTSDREHLRQWQQQLTHA-EQKLNALAAITL----TLTADEVATA 414
+EL W+ +Q W+ L +KL AL L AD
Sbjct: 519 --SELPRFWKKLQIEQG--------WEPALEAVLREKLGALEVSNLDWIKAFAADAPPAK 568
Query: 415 LAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKT 474
LA +A R V + P + + ++ V Q+ ++M+ +
Sbjct: 569 LAFYAPPPAARP--VEAPAGLRPLMSLVQVTEPGMRAVLQDWLADVYIADDMQAALAAR- 625
Query: 475 QQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLA 534
Q L + T Q + R+ +Q P A E + L V LLA
Sbjct: 626 QTLPEGGTFVVQAGHL----IGRSSVQLYAPDSEQAGMLARAQEI-ENLNKQVRAQMLLA 680
Query: 535 LENEVKKLGEEGATLRGQ--LDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITL 592
E + + E A + L + + ++ L+ D L+Q + A
Sbjct: 681 DEAKSAAVRAEAAYSQASQNLTQVRARAEQATRRVHVLQMDVLKLSQAMERYNARSGQID 740
Query: 593 QPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTG 652
L++I+ AQ E +R +R E + H+ + Q + E QQ
Sbjct: 741 SELEEIR----AQIEEQRAIRA-----ESEATFEQHDAALADMQARFEDSQQAF------ 785
Query: 653 YALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEE 712
AL + D A R QE + + E LQNRI +L ++ + +
Sbjct: 786 EALEVRLSDARN---ALRDQERGAQEAHFAERN-LQNRIAELKRNIQVASDQAQ----QI 837
Query: 713 TVVLENWRQ----VHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQA 768
+ LEN R ++EQ H+ Q ++ + L A+ + D D+Q
Sbjct: 838 VLTLENARAELETINEQ--TAHTGLQEALERRAEKEEKLGLARMELDALTAQLRTHDEQR 895
Query: 769 FLAA-----LMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTV 823
A L D T QL++ L NQ + + L + A ++ D +
Sbjct: 896 LTAERAQQPLRDRITELQLKEQAARL-NQEQFTEQLTAANVDEAALAERLTGD------L 948
Query: 824 TVEQIQQELAQTHQKLRENTTSQGEIRQQ-LKQDADNRQQQQTLMQQIAQMTQQVEDWGY 882
+Q E+ + + + + G + L + A R+++ L Q A +T +
Sbjct: 949 KPSYLQGEVTRINNAIN----ALGPVNMAALDELAAARERKGFLDAQSADLTDAITT--- 1001
Query: 883 LNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHG--RYLLQRKASEALEVEVVDTW 940
L I K + R QG T D + + + L G + L E L+ V
Sbjct: 1002 LEDAI-RKIDQETRALLQG-TFDQVNYHFGELFPTLFGGGQAKLMMTGEEILDAGVQVMA 1059
Query: 941 QADAVRDT--RTLSGGESFLVSLALALALSDL 970
Q +++ LSGGE L ++AL A+ L
Sbjct: 1060 QPPGKKNSTIHLLSGGEKALTAIALVFAMFQL 1091