Pairwise Alignments

Query, 458 a.a., Malate-2H(+)/Na(+)-lactate antiporter from Alteromonas macleodii MIT1002

Subject, 533 a.a., Na+/H+ antiporter from Vibrio cholerae E7946 ATCC 55056

 Score =  216 bits (549), Expect = 2e-60
 Identities = 144/490 (29%), Positives = 253/490 (51%), Gaps = 42/490 (8%)

Query: 4   MSVIPPLVAIAVVFWKKEVILALALAVLCAEALILVNADIAGS--YMAPINAIERVVDTA 61
           +SV+PPLVA+++    + V+L+L + +    AL+L +  I  S  Y+A       V + A
Sbjct: 11  LSVLPPLVALSLAIVTRRVLLSLGVGIFLG-ALLLADYSIGQSLQYIATQVGSVFVKEGA 69

Query: 62  ASPGNTRVLIFSVLVGALLAFIRDSGGVTATVNFLVNKGVAKSRKQVGGLTMFTGIAVFI 121
            +  N  ++ F +L+G + A +  SGG  A   +   +   KS++    L  F G+ +F+
Sbjct: 70  INAWNMSIVGFLLLLGMMTALLTLSGGTRAFAQWAQVR--VKSKRGSKLLAAFLGVFIFV 127

Query: 122 ESNLSVLTAGIFARGLFDRFGMSRARLAYIIDSTSAPVCILILLNGWGAFILSLLDAYEL 181
           +   + L  G  +R + DRF +SRA+LAYI+DST+AP+C+++  + WGA+I++++    +
Sbjct: 128 DDYFNSLAVGSISRPVTDRFYVSRAKLAYILDSTAAPMCVVMPASSWGAYIMTIIGGILV 187

Query: 182 -----PASSASVLWGSVFFNFYAIFTLLIVAYTISADKVHGPMAEEEKALTH-------- 228
                  S+       V  NFYAIF LL+V   +      G M + E A +         
Sbjct: 188 SHGIEEYSALGAYLRLVPMNFYAIFALLMVFAVVWFQMDIGQMRKHEIAASQGRGFDEDP 247

Query: 229 -------VEVNQTTEPATKAR----FMLVPLIIMVLSMVGFMFWTGNGVLSEGSGSKSVL 277
                   E+N+  +     R     +++P++ +V++ +G M WTG   L+E   S  + 
Sbjct: 248 STDTQEAHELNEELDIRESERGTVLDLVLPIVFLVVATIGAMIWTGASALAESGQSFDIF 307

Query: 278 YA---TALATAIAYG---------LLLIHKRFTHKEAVEIGFKGMGELLPLVTIVLLSLT 325
            A   T + T++ YG         + ++ ++    E  +  + G   +   + I++ + T
Sbjct: 308 GAFENTNVGTSLVYGGLVGLAMAFVTVLRQKLPTAEIAKTLWIGAKSMFGAILILIFAWT 367

Query: 326 LGNSLKVLGTGVFVAGIVGEYLPLVLIVPMLFIAGAIMSFTTGTSWGTFAILIPIGVPLI 385
           +G+ +  + TG +++ +V   +    +  +LF+    M+F+TGTSWGTF I++PI   + 
Sbjct: 368 IGSVIGDMKTGAYLSSLVQGNIDPHWLPVILFVLSGAMAFSTGTSWGTFGIMLPIAGDMA 427

Query: 386 QSLGLPPSL-VIGAILGGGIFGDHCSPISDTTAVSSLAAGTDVLTHVKTQFPYALFAGAL 444
            +  +   L ++GA+L G +FGDHCSPISDTT +SS  A    + HV TQ PYAL    +
Sbjct: 428 GATDIALMLPMLGAVLAGSVFGDHCSPISDTTILSSTGARCHHIDHVATQLPYALAVALV 487

Query: 445 TLIAYFVASL 454
           + I Y V  +
Sbjct: 488 SAIGYVVLGI 497