Pairwise Alignments

Query, 308 a.a., hydroxymethylglutaryl-CoA lyase from Agrobacterium fabrum C58

Subject, 514 a.a., 2-isopropylmalate synthase from Methanococcus maripaludis S2

 Score = 70.1 bits (170), Expect = 1e-16
 Identities = 74/312 (23%), Positives = 136/312 (43%), Gaps = 23/312 (7%)

Query: 1   MDWPRNVKIVEVGARDGLQNESAEVSTAIKIELIERLAAAGLPAVEAGAFVSPRKVPQMA 60
           M  P  V++ +   RDG Q     +    K+++ + L+  G+ A+EAG  VS     +  
Sbjct: 18  MKLPEKVRVFDTTLRDGEQTPGVSLMPDQKMDIAKNLSEIGVDAIEAGFPVSSEGEQESI 77

Query: 61  DSREVFQGLKRWPGTAYAALVPNMKGFEAAIEAGVTEIAVFVSASDGFSRHNIGCSRAES 120
            +           G A A      K  + AI+ GV  I  F++ S     + +  S+   
Sbjct: 78  KNITSLGLDAEICGLARAV----KKDIDVAIDCGVDSIHTFIATSPLHREYKLKMSK--- 130

Query: 121 LERLRDVAEAAADRNIRMRGYVSCIAGCPYDGAVAP-DDVAAMAEALVALGCYEISLGDT 179
            E++ D+A  + +  I+  G +  +     D      D +  + +  V  G   I++ DT
Sbjct: 131 -EKIIDIAVESIEY-IKEHGVI--VEFSAEDATRTELDYLKEVYKKAVEAGADRINVPDT 186

Query: 180 IGVGTAGQIRDVIERVATGIPRDQIAMHFHDTYGQGVANVLASLQEGIVVFDSSVAGLGG 239
           +GV     +  +I+ +   I +  I++H H+ +G  V+N +A+++ G      +V GLG 
Sbjct: 187 VGVMVPNSMSYLIKELKNDI-KVPISVHCHNDFGIAVSNSVAAVEAGAEQVHCTVNGLG- 244

Query: 240 CPFAPGASGNVATEDVVYLLQGL-GIETGIDLMAVAKTGEWISRHLG---RPNAARAGKA 295
                  +GN + E+ V  L  + GI T ++   + K  + +S + G   +PN A  G+ 
Sbjct: 245 -----ERAGNASLEETVMTLNMVYGINTNVNTKMLTKLSKLVSHYTGIKTQPNKAIVGEN 299

Query: 296 LLAAKQEGDLHG 307
             A +     HG
Sbjct: 300 SFAHESGIHAHG 311