Pairwise Alignments

Query, 606 a.a., DNA mismatch repair protein MutL from Agrobacterium fabrum C58

Subject, 653 a.a., DNA mismatch repair protein MutL from Vibrio cholerae E7946 ATCC 55056

 Score =  257 bits (656), Expect = 1e-72
 Identities = 196/596 (32%), Positives = 284/596 (47%), Gaps = 55/596 (9%)

Query: 1   MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNG 60
           M I+ L   L NQIAAGEV+ERP+S  KELVEN++DAGATRI+I    GG  L+RI DNG
Sbjct: 1   MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNG 60

Query: 61  SGMSPADLELAVRRHCTSKIST--TLDDIRTLGFRGEALPSIGSVAKLTITSRQQGAEQG 118
           SG+   +L LA+ RH TSKI T   L+ I +LGFRGEAL SI SV++LT+TSR    E+ 
Sbjct: 61  SGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEA 120

Query: 119 -SVISVTGGKVSDVRPAASNAGTIVEVRDLFFATPARLKFLKTERAEAAAITEVVKRMAI 177
            S  S        ++PAA   GT VEV DLFF TPAR KFL+TE+ E   I E++KR+A+
Sbjct: 121 WSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIAL 180

Query: 178 AFPHIRFVL--SGTDRSTLEIPSTGDDHLARMAQILGAEFKDNAIEIDAGREDVTLTGFA 235
           +   + F L  +G         +T      R+A + G  F  + + I+   + + L G+ 
Sbjct: 181 SRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWI 240

Query: 236 GVPTFNRGNSSHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSITLDPAFVDV 295
             P   R  S  QY +VNGR ++DKL+  AIR +Y  ++   ++   VL I LDP  VDV
Sbjct: 241 TTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDV 300

Query: 296 NVHPAKSDVRFRDPGLIRGLIVGAIRQALTRDGDRAATT---GASQMMNA---FRPGYSP 349
           NVHPAK +VRF    L+   I  A+  AL +     A T   GA  + +      P   P
Sbjct: 301 NVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVP 360

Query: 350 SGLRPSPSATWSAA-TSPSRPLAVSGDMQFAEAAQSRFSD-------ITMPTARAEPREA 401
                     W A   +P  P     D    E+   +  +       +  P   +  +E 
Sbjct: 361 MIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTGKER 420

Query: 402 YEASQSPSPEPVLY----------------------------------PLGAARAQLHEN 427
           Y ++     E  +Y                                   LG A   +   
Sbjct: 421 YGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKLGKAIQVVAGQ 480

Query: 428 YIIAQTENGLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDLPEEDCDRLMDH 487
           Y++  +  G V++  + A ++L    + NA H     +Q LL+P  + L E +      H
Sbjct: 481 YLLMSSPQGCVLISLYQA-QQLKLRGLLNAQHGAL-KAQPLLVPLALKLNESEWQVAQRH 538

Query: 488 AAGFDALGLVIERFGPGAIAVRETPAMLGEVNVQGLVRQLADEIAEWDAASTLANK 543
           ++    LG+ ++     +I V   P  L + N+Q L+  L    A    +  L+++
Sbjct: 539 SSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSESQALSHQ 594