SEED Subsystems in Cupriavidus basilensis FW507-4G11

Subsystems are shown if they have at least one gene assigned to them. Because many roles are assigned to more than one subsystem, the subsystem may not be present even if the gene annotation(s) are correct.

Category Subsystem #Genes
Amino Acids and Derivatives L-2-amino-thiazoline-4-carboxylic acid-Lcysteine conversion 4
Amino Acids and Derivatives : Alanine, serine, and glycine Alanine biosynthesis 8
  Glycine Biosynthesis 5
  Glycine and Serine Utilization 35
  Glycine cleavage system 6
  Serine Biosynthesis 21
Amino Acids and Derivatives : Arginine; urea cycle, polyamines Arginine Biosynthesis extended 13
  Arginine Deiminase Pathway 1
  Arginine and Ornithine Degradation 17
  Cyanophycin Metabolism 2
  Polyamine Metabolism 8
  Urea decomposition 19
Amino Acids and Derivatives : Aromatic amino acids and derivatives Aromatic amino acid degradation 21
  Aromatic amino acid interconversions with aryl acids 7
  Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. 6
  Chorismate Synthesis 13
  Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) 11
  Phenylalanine and Tyrosine Branches from Chorismate 3
  Tryptophan synthesis 6
Amino Acids and Derivatives : Branched-chain amino acids Branched-Chain Amino Acid Biosynthesis 39
  HMG CoA Synthesis 23
  Isoleucine degradation 80
  Ketoisovalerate oxidoreductase 5
  Leucine Biosynthesis 15
  Leucine Degradation and HMG-CoA Metabolism 32
  Valine degradation 84
Amino Acids and Derivatives : Glutamine, glutamate, aspartate, asparagine; ammonia assimilation Glutamate dehydrogenases 2
  Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis 43
  Glutamine synthetases 1
Amino Acids and Derivatives : Histidine Metabolism Histidine Biosynthesis 12
  Histidine Degradation 17
Amino Acids and Derivatives : Lysine, threonine, methionine, and cysteine Cysteine Biosynthesis 23
  Lysine Biosynthesis DAP Pathway 10
  Lysine degradation 4
  Methionine Biosynthesis 30
  Methionine Degradation 18
  Threonine anaerobic catabolism gene cluster 5
  Threonine and Homoserine Biosynthesis 29
  Threonine degradation 10
Amino Acids and Derivatives : Proline and 4-hydroxyproline Proline, 4-hydroxyproline uptake and utilization 21
  Proline Synthesis 4
Carbohydrates Lacto-N-Biose I and Galacto-N-Biose Metabolic Pathway 3
Carbohydrates : CO2 fixation CO2 uptake, carboxysome 1
  Calvin-Benson cycle 11
  Carboxysome 9
  Photorespiration (oxidative C2 cycle) 27
Carbohydrates : Central carbohydrate metabolism Entner-Doudoroff Pathway 37
  Glycolate, glyoxylate interconversions 12
  Glycolysis and Gluconeogenesis 17
  Glycolysis and Gluconeogenesis, including Archaeal enzymes 13
  Methylglyoxal Metabolism 21
  Pentose phosphate pathway 12
  Pyruvate Alanine Serine Interconversions 14
  Pyruvate metabolism I: anaplerotic reactions, PEP 16
  Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate 48
  TCA Cycle 32
Carbohydrates : Di- and oligosaccharides Beta-Glucoside Metabolism 2
  Fructooligosaccharides(FOS) and Raffinose Utilization 1
  Lactose and Galactose Uptake and Utilization 4
  Lactose utilization 1
  Maltose and Maltodextrin Utilization 7
  Sucrose utilization 1
  Sucrose utilization Shewanella 1
  Trehalose Biosynthesis 3
Carbohydrates : Fermentation Acetoin, butanediol metabolism 18
  Acetyl-CoA fermentation to Butyrate 77
  Butanol Biosynthesis 67
  Fermentations: Lactate 3
  Fermentations: Mixed acid 15
Carbohydrates : Glycoside hydrolases Predicted carbohydrate hydrolases 4
Carbohydrates : Monosaccharides 2-Ketogluconate Utilization 3
  D-Galacturonate and D-Glucuronate Utilization 8
  D-galactarate, D-glucarate and D-glycerate catabolism 16
  D-gluconate and ketogluconates metabolism 7
  D-ribose utilization 7
  Deoxyribose and Deoxynucleoside Catabolism 3
  Fructose utilization 3
  Hexose Phosphate Uptake System 1
  L-Arabinose utilization 3
  L-fucose utilization temp 1
  L-rhamnose utilization 3
  Mannose Metabolism 9
  Xylose utilization 3
Carbohydrates : One-carbon Metabolism One-carbon metabolism by tetrahydropterines 4
  Serine-glyoxylate cycle 53
Carbohydrates : Organic acids Isobutyryl-CoA to Propionyl-CoA Module 33
  Lactate utilization 10
  Malonate decarboxylase 10
  Methylcitrate cycle 8
  Propionate-CoA to Succinate Module 8
  Propionyl-CoA to Succinyl-CoA Module 2
  Tricarballylate Utilization 5
Carbohydrates : Sugar alcohols Di-Inositol-Phosphate biosynthesis 1
  Ethanolamine utilization 8
  Glycerol and Glycerol-3-phosphate Uptake and Utilization 20
  Inositol catabolism 1
  Mannitol Utilization 3
  Propanediol utilization 2
  Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization 5
Cell Division and Cell Cycle Bacterial Cytoskeleton 30
  Control of cell elongation - division cycle in Bacilli 1
  Macromolecular synthesis operon 8
  Two cell division clusters relating to chromosome partitioning 14
Cell Wall and Capsule Peptidoglycan Biosynthesis 28
  UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis 7
  YjeE 1
Cell Wall and Capsule : Capsular and extracellular polysacchrides Alginate metabolism 8
  CMP-N-acetylneuraminate Biosynthesis 1
  Capsular heptose biosynthesis 9
  Colanic acid biosynthesis 19
  O-Methyl Phosphoramidate Capsule Modification in Campylobacter 1
  Phosphorylcholine incorporation in LPS 1
  Polysaccharide deacetylases 3
  Rhamnose containing glycans 12
  Sialic Acid Metabolism 9
  dTDP-rhamnose synthesis 9
Cell Wall and Capsule : Cell wall of Mycobacteria linker unit-arabinogalactan synthesis 11
  mycolic acid synthesis 44
Cell Wall and Capsule : Gram-Negative cell wall components KDO2-Lipid A biosynthesis 12
  LOS core oligosaccharide biosynthesis 4
  Lipid A-Ara4N pathway ( Polymyxin resistance ) 6
  Lipid A modifications 2
  Lipopolysaccharide-related cluster in Alphaproteobacteria 1
Cell Wall and Capsule : Gram-Positive cell wall components Teichoic and lipoteichoic acids biosynthesis 2
  Teichuronic acid biosynthesis 3
Clustering-based subsystems Bacterial Cell Division 33
  Bacterial RNA-metabolizing Zn-dependent hydrolases 13
  CBSS-214092.1.peg.3450 2
  CBSS-562.2.peg.5158 SK3 including 2
  Conserved gene cluster associated with Met-tRNA formyltransferase 17
  LMPTP YfkJ cluster 3
  LMPTP YwlE cluster 6
  NusA-TFII Cluster 3
  PA0057 cluster 3
  Putative sulfate assimilation cluster 1
Clustering-based subsystems : Clustering-based subsystems CBSS-262719.3.peg.410 2
  Conenzyme B12 related Hypothetical: Clusters with cobST 2
Clustering-based subsystems : Lysine, threonine, methionine, and cysteine YeiH 3
Clustering-based subsystems : proteosome related Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related 2
Cofactors, Vitamins, Prosthetic Groups, Pigments Thiamin biosynthesis 18
Cofactors, Vitamins, Prosthetic Groups, Pigments : Biotin Biotin biosynthesis 21
Cofactors, Vitamins, Prosthetic Groups, Pigments : Coenzyme A Coenzyme A Biosynthesis 11
Cofactors, Vitamins, Prosthetic Groups, Pigments : Folate and pterines Folate Biosynthesis 23
  Molybdenum cofactor biosynthesis 27
  Pterin biosynthesis 3
  p-Aminobenzoyl-Glutamate Utilization 3
Cofactors, Vitamins, Prosthetic Groups, Pigments : Lipoic acid Lipoic acid metabolism 4
Cofactors, Vitamins, Prosthetic Groups, Pigments : NAD and NADP NAD and NADP cofactor biosynthesis global 19
  NAD regulation 10
  PnuC-like transporters 1
Cofactors, Vitamins, Prosthetic Groups, Pigments : Pyridoxine Pyridoxin (Vitamin B6) Biosynthesis 24
Cofactors, Vitamins, Prosthetic Groups, Pigments : Quinone cofactors Coenzyme PQQ synthesis 5
  Menaquinone and Phylloquinone Biosynthesis 8
  Plastoquinone Biosynthesis 3
  Pyrroloquinoline Quinone biosynthesis 3
  Tocopherol Biosynthesis 3
  Ubiquinone Biosynthesis 11
Cofactors, Vitamins, Prosthetic Groups, Pigments : Riboflavin, FMN, FAD Riboflavin, FMN and FAD metabolism 6
Cofactors, Vitamins, Prosthetic Groups, Pigments : Tetrapyrroles Cobalamin synthesis 7
  Coenzyme B12 biosynthesis 21
  Experimental tye 15
  Heme and Siroheme Biosynthesis 13
DNA Metabolism DNA structural proteins, bacterial 4
  Restriction-Modification System 5
  YcfH 3
DNA Metabolism : DNA recombination RuvABC plus a hypothetical 3
DNA Metabolism : DNA repair 2-phosphoglycolate salvage 4
  DNA Repair Base Excision 12
  DNA repair, UvrABC system 4
  DNA repair, bacterial 27
  DNA repair, bacterial DinG and relatives 1
  DNA repair, bacterial MutL-MutS system 2
  DNA repair, bacterial RecFOR pathway 6
  DNA repair, bacterial UvrD and related helicases 4
DNA Metabolism : DNA replication DNA-replication 29
  DNA replication, archaeal 1
  DNA topoisomerases, Type I, ATP-independent 2
  DNA topoisomerases, Type II, ATP-dependent 5
  Plasmid replication 7
Fatty Acids, Lipids, and Isoprenoids Polyhydroxybutyrate metabolism 75
Fatty Acids, Lipids, and Isoprenoids : Fatty acids Fatty Acid Biosynthesis FASII 56
Fatty Acids, Lipids, and Isoprenoids : Isoprenoids Archaeal lipids 3
  Carotenoids 6
  Isoprenoid Biosynthesis 11
  Polyprenyl Diphosphate Biosynthesis 1
  polyprenyl synthesis 6
Fatty Acids, Lipids, and Isoprenoids : Phospholipids Glycerolipid and Glycerophospholipid Metabolism in Bacteria 55
Fatty Acids, Lipids, and Isoprenoids : Triacylglycerols Triacylglycerol metabolism 3
Iron acquisition and metabolism Campylobacter Iron Metabolism 12
  Heme, hemin uptake and utilization systems in GramPositives 1
  Hemin transport system 8
  Iron acquisition in Vibrio 18
  Transport of Iron 18
Membrane Transport Choline Transport 3
  ECF class transporters 2
  Ton and Tol transport systems 30
  Transport of Manganese 1
  Transport of Molybdenum 7
  Transport of Nickel and Cobalt 2
  Transport of Zinc 3
Membrane Transport : ABC transporters ABC transporter alkylphosphonate (TC 3.A.1.9.1) 9
  ABC transporter branched-chain amino acid (TC 3.A.1.4.1) 68
  ABC transporter dipeptide (TC 3.A.1.5.2) 13
  ABC transporter oligopeptide (TC 3.A.1.5.1) 20
  ABC transporter tungstate (TC 3.A.1.6.2) 3
Membrane Transport : Protein and nucleoprotein secretion system, Type IV Type IV pilus 31
  pVir Plasmid of Campylobacter 1
Membrane Transport : Protein secretion system, Type II Widespread colonization island 17
Membrane Transport : Protein translocation across cytoplasmic membrane Twin-arginine translocation system 4
Membrane Transport : Sugar Phosphotransferase Systems, PTS Fructose and Mannose Inducible PTS 1
Membrane Transport : Uni- Sym- and Antiporters Sodium Hydrogen Antiporter 5
Metabolism of Aromatic Compounds Aromatic Amin Catabolism 7
  Benzoate transport and degradation cluster 25
  Gentisare degradation 25
  carbazol degradation cluster 4
Metabolism of Aromatic Compounds : Metabolism of central aromatic intermediates 4-Hydroxyphenylacetic acid catabolic pathway 10
  Catechol branch of beta-ketoadipate pathway 25
  Central meta-cleavage pathway of aromatic compound degradation 19
  Homogentisate pathway of aromatic compound degradation 50
  N-heterocyclic aromatic compound degradation 12
  Protocatechuate branch of beta-ketoadipate pathway 24
  Salicylate and gentisate catabolism 38
Metabolism of Aromatic Compounds : Peripheral pathways for catabolism of aromatic compounds Benzoate degradation 13
  Biphenyl Degradation 10
  Chloroaromatic degradation pathway 13
  Naphtalene and antracene degradation 3
  Phenylpropanoid compound degradation 22
  Quinate degradation 2
  Salicylate ester degradation 8
  n-Phenylalkanoic acid degradation 52
  p-Hydroxybenzoate degradation 8
Miscellaneous Muconate lactonizing enzyme family 1
  YaaA 1
  YbbK 4
  ZZ gjo need homes 23
Miscellaneous : Plant-Prokaryote DOE project Conserved gene cluster possibly involved in RNA metabolism 3
Motility and Chemotaxis Bacterial Chemotaxis 44
Motility and Chemotaxis : Flagellar motility in Prokaryota Flagellar motility 27
  Flagellum 47
  Flagellum in Campylobacter 4
Nitrogen Metabolism Allantoin Utilization 10
  Ammonia assimilation 19
  Cyanate hydrolysis 5
  Denitrification 5
  Dissimilatory nitrite reductase 1
  Nitrate and nitrite ammonification 35
  Nitric oxide synthase 4
  Nitrogen fixation 1
  Nitrosative stress 7
Nucleosides and Nucleotides Hydantoin metabolism 18
  Ribonucleotide reduction 6
Nucleosides and Nucleotides : Detoxification Nudix proteins (nucleoside triphosphate hydrolases) 7
Nucleosides and Nucleotides : Purines De Novo Purine Biosynthesis 13
  Purine Utilization 10
  Purine conversions 23
Nucleosides and Nucleotides : Pyrimidines De Novo Pyrimidine Synthesis 12
  Pyrimidine utilization 7
Phages, Prophages, Transposable elements : Bacteriophage structural proteins Phage capsid proteins 2
Phages, Prophages, Transposable elements, Plasmids : Pathogenicity islands Staphylococcal pathogenicity islands SaPI 7
Phages, Prophages, Transposable elements, Plasmids : Transposable elements Tn552 2
Phosphorus Metabolism Alkylphosphonate utilization 16
  High affinity phosphate transporter and control of PHO regulon 14
  Phosphate metabolism 37
  Phosphonate metabolism 1
Potassium metabolism Glutathione-regulated potassium-efflux system and associated functions 4
  Potassium homeostasis 14
Protein Metabolism : Protein biosynthesis Ribosome LSU bacterial 30
  Ribosome SSU bacterial 20
  Ribosome activity modulation 1
  Ribosome biogenesis bacterial 9
  Trans-translation by stalled ribosomes 1
  Translation elongation factor G family 4
  Translation elongation factors eukaryotic and archaeal 1
  Translation initiation factors eukaryotic and archaeal 2
  Universal GTPases 17
  tRNA aminoacylation, Glu and Gln 2
Protein Metabolism : Protein degradation Proteasome bacterial 7
  Protein degradation 4
  Proteolysis in bacteria, ATP-dependent 13
  Putative TldE-TldD proteolytic complex 3
Protein Metabolism : Protein folding GroEL GroES 2
  Peptidyl-prolyl cis-trans isomerase 3
  Periplasmic disulfide interchange 7
  Protein chaperones 10
Protein Metabolism : Protein processing and modification N-linked Glycosylation in Bacteria 6
  Ribosomal protein S12p Asp methylthiotransferase 3
  Ribosomal protein S5p acylation 1
  Signal peptidase 2
Protein Metabolism : Selenoproteins Glycine reductase, sarcosine reductase and betaine reductase 7
  Selenocysteine metabolism 2
RNA Metabolism : RNA processing and modification ATP-dependent RNA helicases, bacterial 3
  Polyadenylation bacterial 5
  Queuosine-Archaeosine Biosynthesis 36
  RNA 3'-terminal phosphate cyclase 2
  RNA processing and degradation, bacterial 7
  Ribonuclease H 2
  Wyeosine-MimG Biosynthesis 7
  tRNA nucleotidyltransferase 1
  tRNA processing 9
  tRNA splicing 1
RNA Metabolism : Transcription RNA polymerase bacterial 4
  Rrf2 family transcriptional regulators 5
  Transcription factors bacterial 8
  Transcription factors cyanobacterial RpoD-like sigma factors 2
  Transcription initiation, bacterial sigma factors 11
Regulation and Cell signaling DNA-binding regulatory proteins, strays 21
  Orphan regulatory proteins 15
  Sex pheromones in Enterococcus faecalis and other Firmicutes 7
  Stringent Response, (p)ppGpp metabolism 2
  Two-component regulatory systems in Campylobacter 10
  cAMP signaling in bacteria 18
Regulation and Cell signaling : Programmed Cell Death and Toxin-antitoxin Systems Murein hydrolase regulation and cell death 8
Regulation and Cell signaling : Quorum sensing and biofilm formation Quorum Sensing: Autoinducer-2 Synthesis 2
Respiration Biogenesis of c-type cytochromes 7
  Biogenesis of cbb3-type cytochrome c oxidases 3
  Biogenesis of cytochrome c oxidases 10
  Carbon monoxide dehydrogenase maturation factors 3
  Formate hydrogenase 11
  Soluble cytochromes and functionally related electron carriers 18
Respiration : ATP synthases F0F1-type ATP synthase 6
Respiration : Electron accepting reactions Anaerobic respiratory reductases 32
  Terminal cytochrome C oxidases 19
  Terminal cytochrome O ubiquinol oxidase 12
  Terminal cytochrome d ubiquinol oxidases 6
  Terminal cytochrome oxidases 18
  Ubiquinone Menaquinone-cytochrome c reductase complexes 3
Respiration : Electron donating reactions CO Dehydrogenase 8
  Formate dehydrogenase 1
  Respiratory Complex I 14
  Respiratory dehydrogenases 1 17
  Succinate dehydrogenase 8
Secondary Metabolism : Aromatic amino acids and derivatives Cinnamic Acid Degradation 9
Secondary Metabolism : Bacterial cytostatics, differentiation factors and antibiotics Phenazine biosynthesis 1
Secondary Metabolism : Biologically active compounds in metazoan cell defence and differentiation Quinolinic acid and its derivatives 1
Secondary Metabolism : Biosynthesis of phenylpropanoids Biflavanoid biosynthesis 2
  Phenylpropionate Degradation 1
  Tannin biosynthesis 2
Secondary Metabolism : Plant Hormones Auxin biosynthesis 5
  Auxin degradation 2
Stress Response Bacterial hemoglobins 27
  Dimethylarginine metabolism 1
  Flavohaemoglobin 3
  Hfl operon 5
  SigmaB stress responce regulation 1
  Universal stress protein family 3
Stress Response : Acid stress Acid resistance mechanisms 1
Stress Response : Detoxification Glutathione-dependent pathway of formaldehyde detoxification 3
Stress Response : Heat shock Heat shock dnaK gene cluster extended 16
Stress Response : Osmotic stress Choline and Betaine Uptake and Betaine Biosynthesis 16
Stress Response : Oxidative stress Glutaredoxins 4
  Glutathione: Biosynthesis and gamma-glutamyl cycle 11
  Glutathione: Non-redox reactions 20
  Glutathione: Redox cycle 2
  Glutathionylspermidine and Trypanothione 1
  Oxidative stress 33
  Redox-dependent regulation of nucleus processes 5
  Rubrerythrin 8
Sulfur Metabolism Galactosylceramide and Sulfatide metabolism 1
  Sulfur oxidation 18
  Thioredoxin-disulfide reductase 15
Sulfur Metabolism : Organic sulfur assimilation Alkanesulfonate assimilation 28
  Alkanesulfonates Utilization 14
  Taurine Utilization 10
  Utilization of glutathione as a sulphur source 7
Virulence : Type III, Type IV, Type VI, ESAT secretion systems Type 4 secretion and conjugative transfer 9
Virulence, Disease and Defense : Adhesion Streptococcus pyogenes recombinatorial zone 1
Virulence, Disease and Defense : Detection MLST 9
Virulence, Disease and Defense : Resistance to antibiotics and toxic compounds Arsenic resistance 6
  Beta-lactamase 8
  Cobalt-zinc-cadmium resistance 35
  Copper homeostasis 9
  Copper homeostasis: copper tolerance 5
  Mercuric reductase 1
  Methicillin resistance in Staphylococci 2
  Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria 14
  Multidrug Resistance Efflux Pumps 28
  Multidrug efflux pump in Campylobacter jejuni (CmeABC operon) 12
  Resistance to fluoroquinolones 5
  Zinc resistance 2