| Role | Gene | Name | |
| 4-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) | Pf6N2E2_3126 | | |
| | Pf6N2E2_3131 | | |
| 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) | No genes | | |
| ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) | Pf6N2E2_1338 | | |
| | Pf6N2E2_1744 | | |
| | Pf6N2E2_3127 | | |
| | Pf6N2E2_4816 | | |
| | Pf6N2E2_5477 | | |
| Agmatinase (EC 3.5.3.11) | Pf6N2E2_2655 | | |
| Agmatine deiminase (EC 3.5.3.12) | Pf6N2E2_3876 | | |
| Agmatine/putrescine antiporter, associated with agmatine catabolism | No genes | | |
| Arginine decarboxylase (EC 4.1.1.19) | Pf6N2E2_3334 | | |
| Arginine decarboxylase, catabolic (EC 4.1.1.19) | No genes | | |
| Arginine/agmatine antiporter | No genes | | |
| Arginine/ornithine antiporter | No genes | | |
| Arginine/ornithine antiporter ArcD | Pf6N2E2_1517 | | |
| | Pf6N2E2_2906 | | |
| | Pf6N2E2_2907 | | |
| Biosynthetic arginine decarboxylase (EC 4.1.1.19) | Pf6N2E2_3504 | | |
| Carbamate kinase (EC 2.7.2.2) | Pf6N2E2_2910 | | |
| Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) | Pf6N2E2_1606 | | |
| Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) | Pf6N2E2_1605 | | |
| DNA-binding response regulator, LuxR family, near polyamine transporter | Pf6N2E2_1774 | | |
| | Pf6N2E2_4814 | | |
| N-carbamoylputrescine amidase (3.5.1.53) | No genes | | |
| Ornithine decarboxylase (EC 4.1.1.17) | Pf6N2E2_3334 | | |
| Predicted chaperone lipoprotein YacC, potentially involved in protein secretion | No genes | | |
| Predicted polyamine sensor NspS, involved in biofilm formation | No genes | | |
| Probable spermidine/putrescine substrate binding protein in Mollicutes | No genes | | |
| Probable two-component sensor, near polyamine transporter | Pf6N2E2_4813 | | |
| Putative GntR-family regulatory protein and aminotransferase near polyamine transporter | No genes | | |
| Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) | Pf6N2E2_1425 | | |
| | Pf6N2E2_1770 | | |
| | Pf6N2E2_4290 | | |
| | Pf6N2E2_4513 | | |
| | Pf6N2E2_4514 | | |
| Putrescine carbamoyltransferase (EC 2.1.3.6) | No genes | | |
| Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) | Pf6N2E2_1743 | | |
| | Pf6N2E2_3128 | | |
| | Pf6N2E2_4815 | | |
| | Pf6N2E2_5480 | | |
| Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) | Pf6N2E2_4515 | | |
| Putrescine transport system permease protein PotH (TC 3.A.1.11.2) | Pf6N2E2_4516 | | |
| Putrescine transport system permease protein PotI (TC 3.A.1.11.2) | Pf6N2E2_4517 | | |
| Putrescine-ornithine antiporter | No genes | | |
| Putrescine/proton symporter, putrescine/ornithine antiporter PotE | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), eukaryotic | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1B | No genes | | |
| Spermidine N1-acetyltransferase (EC 2.3.1.57) | No genes | | |
| Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) | Pf6N2E2_1745 | | |
| | Pf6N2E2_3129 | | |
| | Pf6N2E2_4817 | | |
| Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) | Pf6N2E2_1746 | | |
| | Pf6N2E2_3130 | | |
| | Pf6N2E2_4818 | | |
| Spermidine synthase (EC 2.5.1.16) | Pf6N2E2_2452 | | |
| Transcriptional regulator of catabolic arginine decarboxylase (adiA) | No genes | | |
| Transcriptional regulator, MerR family, near polyamine transporter | No genes | | |
| Transcriptional regulator, TetR family, associated with agmatine catabolism | No genes | | |
| Transcriptional regulator, luxR family, associated with agmatine catabolism | No genes | | |