SEED Subsystem: Methionine Biosynthesis in Pseudomonas fluorescens FW300-N2E2

Experiments:

Role Gene Name  
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) Pf6N2E2_4638
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) Pf6N2E2_2068
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) Pf6N2E2_5472
Adenosylhomocysteinase (EC 3.3.1.1) Pf6N2E2_4639
Archaeal S-adenosylmethionine synthetase (EC 2.5.1.6) No genes
Betaine--homocysteine S-methyltransferase (EC 2.1.1.5) No genes
Cystathionine beta-lyase (EC 4.4.1.8) Pf6N2E2_1491
Cystathionine beta-lyase, type II (EC 4.4.1.8) No genes
Cystathionine beta-synthase (EC 4.2.1.22) No genes
Cystathionine gamma-lyase (EC 4.4.1.1) Pf6N2E2_5896
Cystathionine gamma-synthase (EC 2.5.1.48) Pf6N2E2_4958
Cysteine synthase (EC 2.5.1.47) Pf6N2E2_2700
  Pf6N2E2_2936
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter No genes
Homocysteine S-methyltransferase (EC 2.1.1.10) Pf6N2E2_4283
Homoserine O-acetyltransferase (EC 2.3.1.31) Pf6N2E2_4596
  Pf6N2E2_4597
Homoserine O-succinyltransferase (EC 2.3.1.46) No genes
Homoserine dehydrogenase (EC 1.1.1.3) Pf6N2E2_3143
  Pf6N2E2_4963
Homoserine kinase (EC 2.7.1.39) Pf6N2E2_4164
  Pf6N2E2_6055
Methionine ABC transporter ATP-binding protein Pf6N2E2_3927
  Pf6N2E2_4172
  Pf6N2E2_4912
Methionine ABC transporter permease protein Pf6N2E2_3928
  Pf6N2E2_4173
Methionine ABC transporter substrate-binding protein Pf6N2E2_3926
  Pf6N2E2_3953
  Pf6N2E2_4174
Methionine repressor MetJ No genes
Methionine synthase activation domain (EC 2.1.1.13) No genes
Methionine transporter MetT No genes
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) Pf6N2E2_1768
  Pf6N2E2_1876
  Pf6N2E2_77
O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) Pf6N2E2_77
Predicted regulator of methionine metabolism, ArsR family No genes
S-adenosylhomocysteine nucleosidase (EC 3.2.2.9) No genes
S-adenosylmethionine synthetase (EC 2.5.1.6) Pf6N2E2_4652
S-ribosylhomocysteine lyase (EC 4.4.1.21) No genes
SAM-dependent methlytransferase UbiG No genes
SAM-dependent methlytransferase YrrT No genes
Serine acetyltransferase (EC 2.3.1.30) Pf6N2E2_3191
Substrate-specific component MtsA of methionine-regulated ECF transporter No genes
Transcriptional activator MetR Pf6N2E2_5471
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter No genes

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