| Role | Gene | Name | |
| 4-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) | SMc01656 | | |
| 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) | SMc00395 | | |
| ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) | SM_b20284 | | |
| | SM_b21273 | | |
| | SMa1755 | | |
| | SMc01632 | | |
| | SMc01652 | | |
| Agmatinase (EC 3.5.3.11) | SMc01802 | | |
| | SMc01967 | | |
| Agmatine deiminase (EC 3.5.3.12) | No genes | | |
| Agmatine/putrescine antiporter, associated with agmatine catabolism | No genes | | |
| Arginine decarboxylase (EC 4.1.1.19) | SMc02983 | | |
| Arginine decarboxylase, catabolic (EC 4.1.1.19) | No genes | | |
| Arginine/agmatine antiporter | No genes | | |
| Arginine/ornithine antiporter | No genes | | |
| Arginine/ornithine antiporter ArcD | SMa1050 | | |
| | SMa1667 | | |
| | SMa1668 | | |
| | SMc02855 | | |
| Biosynthetic arginine decarboxylase (EC 4.1.1.19) | No genes | | |
| Carbamate kinase (EC 2.7.2.2) | SMa0697 | | |
| Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) | No genes | | |
| Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) | No genes | | |
| DNA-binding response regulator, LuxR family, near polyamine transporter | No genes | | |
| N-carbamoylputrescine amidase (3.5.1.53) | No genes | | |
| Ornithine decarboxylase (EC 4.1.1.17) | SMc02983 | | |
| Predicted chaperone lipoprotein YacC, potentially involved in protein secretion | No genes | | |
| Predicted polyamine sensor NspS, involved in biofilm formation | SMc00991 | | |
| Probable spermidine/putrescine substrate binding protein in Mollicutes | No genes | | |
| Probable two-component sensor, near polyamine transporter | No genes | | |
| Putative GntR-family regulatory protein and aminotransferase near polyamine transporter | No genes | | |
| Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) | SMc00770 | | |
| Putrescine carbamoyltransferase (EC 2.1.3.6) | No genes | | |
| Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) | SM_b20281 | | |
| | SM_b20380 | | |
| | SMa0391 | | |
| | SMa0526 | | |
| | SMa0953 | | |
| | SMa1754 | | |
| | SMc01631 | | |
| | SMc01653 | | |
| | SMc01965 | | |
| Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) | SMc00771 | | |
| | SMc04393 | | |
| Putrescine transport system permease protein PotH (TC 3.A.1.11.2) | SM_b20382 | | |
| | SMc00772 | | |
| Putrescine transport system permease protein PotI (TC 3.A.1.11.2) | SMc00773 | | |
| Putrescine-ornithine antiporter | No genes | | |
| Putrescine/proton symporter, putrescine/ornithine antiporter PotE | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), eukaryotic | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A | No genes | | |
| S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1B | No genes | | |
| Spermidine N1-acetyltransferase (EC 2.3.1.57) | No genes | | |
| Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) | SM_b20283 | | |
| | SM_b21274 | | |
| | SMa0952 | | |
| | SMa1753 | | |
| | SMc01633 | | |
| | SMc01654 | | |
| Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) | SM_b20282 | | |
| | SM_b21275 | | |
| | SMa1751 | | |
| | SMc01634 | | |
| | SMc01655 | | |
| Spermidine synthase (EC 2.5.1.16) | No genes | | |
| Transcriptional regulator of catabolic arginine decarboxylase (adiA) | No genes | | |
| Transcriptional regulator, MerR family, near polyamine transporter | No genes | | |
| Transcriptional regulator, TetR family, associated with agmatine catabolism | No genes | | |
| Transcriptional regulator, luxR family, associated with agmatine catabolism | No genes | | |