| Role | Gene | Name | |
|---|
| 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) | Shew_0547 | | |
| ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) | Shew_2508 | clpP | |
| Adenine phosphoribosyltransferase (EC 2.4.2.7) | Shew_2236 | | |
| Adenylate cyclase (EC 4.6.1.1) | Shew_0319 | cyaA | |
| | Shew_0619 | | |
| | Shew_1036 | | |
| | Shew_1517 | | |
| Adenylate/guanylate cyclase (EC 4.6.1.2) | No genes | | |
| CAMP phosphodiesterases class-II:Metallo-beta-lactamase superfamily | No genes | | |
| Cyclic AMP receptor protein | Shew_0585 | | |
| ElaA protein | Shew_3397 | | |
| Heme-regulated cyclic AMP phosphodiesterase (EC 3.1.4.-) | No genes | | |
| Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase | Shew_0589 | | |
| Predicted signal-transduction protein containing cAMP-binding and CBS domains | Shew_0051 | | |
| | Shew_2369 | | |
| Prophage Clp protease-like protein | No genes | | |
| Purine cyclase-related protein | No genes | | |
| Putative Heme-regulated two-component response regulator | No genes | | |
| Putative hemin-binding lipoprotein | No genes | | |
| Putative insecticidal toxin complex | No genes | | |
| adenylate cyclase ExoY | No genes | | |
| anthrax toxin moiety, protective antigen, pagA formerly pag, plasmid pXO1, B. anthracis (M22589, P13423) | No genes | | |
| bifunctional hemolysin-adenylate cyclase precursor | No genes | | |
| cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | Shew_2699 | | |
| cAMP-dependent Kef-type K+ transport system | Shew_0620 | | |
| calmodulin sensitive adenylate cyclase, edema factor, cya, plasmid pXO1, B. anthracis (M23179, M24074) | No genes | | |
| cyclolysin secretion ATP-binding protein | No genes | | |
| cyclolysin secretion protein | No genes | | |
| cyclolysin-activating lysine-acyltransferase | No genes | | |
| trans-acting positive regulator (Atx A) | No genes | | |
| transcriptional activator AtxA, (pXO1-119) | No genes | | |