SEED Subsystem: Folate Biosynthesis in Shewanella loihica PV-4

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) Shew_1003
  Shew_3132
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Shew_3069
5-nucleotidase SurE (EC 3.1.3.5) No genes
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) Shew_1577
COG0488: ATPase components of ABC transporters with duplicated ATPase domains No genes
Dihydrofolate reductase (EC 1.5.1.3) Shew_0874
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) Shew_1002
Dihydroneopterin triphosphate epimerase Shew_2399 folX
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) Shew_2833
FolM Alternative dihydrofolate reductase 1 Shew_0048
  Shew_2034
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) Shew_0443
GTP cyclohydrolase I (EC 3.5.4.16) type 1 Shew_3486 folE
GTP cyclohydrolase I (EC 3.5.4.16) type 2 No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9) Shew_3737
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) Shew_2510
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) Shew_0575
  Shew_2532
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) Shew_1903
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase No genes
Serine hydroxymethyltransferase (EC 2.1.2.1) Shew_1185 glyA
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) Shew_2579
Thymidylate synthase (EC 2.1.1.45) Shew_1041 thyA
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) Shew_1089
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase No genes
alternate gene name: yzbB No genes

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