SEED Subsystem: Folate Biosynthesis in Methanococcus maripaludis S2

Experiments:

Role Gene Name  
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) No genes
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) No genes
5-nucleotidase SurE (EC 3.1.3.5) MMP_RS05435
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12) No genes
ATPase component of general energizing module of ECF transporters No genes
Alternative Folylglutamate Synthase No genes
Alternative dihydrofolate reductase 2 No genes
Alternative dihydrofolate reductase 3 No genes
Aminodeoxychorismate lyase (EC 4.1.3.38) No genes
COG0488: ATPase components of ABC transporters with duplicated ATPase domains No genes
Dihydrofolate reductase (EC 1.5.1.3) No genes
Dihydrofolate synthase (EC 6.3.2.12) No genes
Dihydroneopterin aldolase (EC 4.1.2.25) No genes
Dihydroneopterin triphosphate epimerase No genes
Dihydroneopterin triphosphate pyrophosphohydolase No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2 No genes
Dihydropteroate synthase (EC 2.5.1.15) No genes
FolM Alternative dihydrofolate reductase 1 No genes
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB) No genes
Folate transporter 3 No genes
Folylpolyglutamate synthase (EC 6.3.2.17) No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3) No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1 No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 2 MMP_RS00220
Methionyl-tRNA formyltransferase (EC 2.1.2.9) No genes
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) No genes
Non functional Dihydropteroate synthase 2 No genes
Nucleoside triphosphate pyrophosphohydrolase MazG No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) No genes
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) No genes
PqqC-like protein No genes
Putative DHNTP pyrophosphatase No genes
Related to Dihydropteroate synthase MMP_RS08125
Serine hydroxymethyltransferase (EC 2.1.2.1) No genes
Substrate-specific component FolT of folate ECF transporter No genes
Thymidine kinase (EC 2.7.1.21) No genes
Thymidylate synthase (EC 2.1.1.45) MMP_RS05105
  MMP_RS07105
Thymidylate synthase thyX (EC 2.1.1.-) No genes
Transaldolase (EC 2.2.1.2) MMP_RS06740
Transmembrane component of general energizing module of ECF transporters No genes
Xanthosine/inosine triphosphate pyrophosphatase MMP_RS01180
alternate gene name: yzbB No genes

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