SEED Subsystem: Coenzyme B12 biosynthesis in Methanococcus maripaludis JJ

Experiments:

Role Gene Name  
5,6-dimethylbenzimidazole synthase, flavin destructase family No genes
ATPase component CbiO of energizing module of cobalt ECF transporter MMJJ_RS06730
Additional lipoprotein component of predicted cobalamin ECF transporter No genes
Additional substrate-specific component CbiN of cobalt ECF transporter MMJJ_RS06740
Adenosylcobinamide amidohydrolase (EC 3.5.1.90) No genes
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) No genes
Adenosylcobinamide-phosphate synthase No genes
Aerobic cobaltochelatase CobS subunit (EC 6.6.1.2) No genes
Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) No genes
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) No genes
CblX, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblY, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
CblZ, a non-orthologous displasment for Alpha-ribazole-5'-phosphate phosphatase No genes
ChlD component of cobalt chelatase involved in B12 biosynthesis MMJJ_RS02320
ChlI component of cobalt chelatase involved in B12 biosynthesis MMJJ_RS02320
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) No genes
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) No genes
Cob(II)alamin reductase No genes
CobN component of cobalt chelatase involved in B12 biosynthesis No genes
CobW GTPase involved in cobalt insertion for B12 biosynthesis No genes
Cobalamin biosynthesis protein CbiG MMJJ_RS06185
Cobalamin biosynthesis protein CobG No genes
Cobalamin synthase No genes
Cobalamine-related hypothetical metal-binding protein CrdX No genes
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) MMJJ_RS03670
Cobalt-precorrin-3b C17-methyltransferase MMJJ_RS00195
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) MMJJ_RS05810
Cobalt-precorrin-6 synthase, anaerobic MMJJ_RS08155
Cobalt-precorrin-6x reductase (EC 1.3.1.54) MMJJ_RS01915
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) MMJJ_RS08065
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) MMJJ_RS08035
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) MMJJ_RS03615
Cobyric acid synthase No genes
Cobyrinic acid A,C-diamide synthase MMJJ_RS05295
  MMJJ_RS06760
Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter No genes
HoxN/HupN/NixA family cobalt transporter No genes
HupE-UreJ family cobalt transporter No genes
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) MMJJ_RS04110
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) MMJJ_RS03580
Optional hypothetical component of the B12 transporter BtuM No genes
Optional hypothetical component of the B12 transporter BtuN No genes
Outer membrane vitamin B12 receptor BtuB No genes
Precorrin-6A synthase (EC 2.1.1.152) No genes
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) MMJJ_RS00385
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) MMJJ_RS06155
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis No genes
Predicted cobalt ABC transporter periplasmic component No genes
Predicted cobalt transporter CbtA No genes
Predicted cobalt transporter CbtC No genes
Predicted cobalt transporter in Bacteroides_Porphyromonas No genes
Predicted cobalt transporter in Mycobacteria No genes
Predicted cobalt transporter in Thermoplasma No genes
Predicted cobalt transporter in sulfate-reducing delta-proteobacteria No genes
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis No genes
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) MMJJ_RS04565
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) No genes
Substrate-specific component CbiM of cobalt ECF transporter MMJJ_RS06745
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole No genes
Substrate-specific component CbrT of predicted cobalamin ECF transporter No genes
Threonine kinase in B12 biosynthesis No genes
Transmembrane component CbiQ of energizing module of cobalt ECF transporter MMJJ_RS06735
Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter No genes
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) MMJJ_RS00130
Vitamin B12 ABC transporter, ATPase component BtuD MMJJ_RS02330
Vitamin B12 ABC transporter, B12-binding component BtuF MMJJ_RS01450
  MMJJ_RS02335
Vitamin B12 ABC transporter, permease component BtuC MMJJ_RS04280

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