SEED Subsystem: Folate Biosynthesis in Erwinia tracheiphila HP pepo 2.2

Role	Gene	Name
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3)	IJEDHG_15045	folK
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	IJEDHG_03315
5-nucleotidase SurE (EC 3.1.3.5)	IJEDHG_17485	surE
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12)	No genes
ATPase component of general energizing module of ECF transporters	No genes
Alternative Folylglutamate Synthase	No genes
Alternative dihydrofolate reductase 2	No genes
Alternative dihydrofolate reductase 3	No genes
Aminodeoxychorismate lyase (EC 4.1.3.38)	IJEDHG_00665	pabC
COG0488: ATPase components of ABC transporters with duplicated ATPase domains	No genes
Dihydrofolate reductase (EC 1.5.1.3)	IJEDHG_06150	folA
Dihydrofolate synthase (EC 6.3.2.12)	IJEDHG_06125	folC
	IJEDHG_17900	folC
Dihydroneopterin aldolase (EC 4.1.2.25)	IJEDHG_14360	folB
Dihydroneopterin triphosphate epimerase	No genes
Dihydroneopterin triphosphate pyrophosphohydolase	No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2	IJEDHG_22120	nudB
Dihydropteroate synthase (EC 2.5.1.15)	IJEDHG_13900	folP
FolM Alternative dihydrofolate reductase 1	No genes
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB)	No genes
Folate transporter 3	No genes
Folylpolyglutamate synthase (EC 6.3.2.17)	IJEDHG_06125	folC
	IJEDHG_17900	folC
Formate--tetrahydrofolate ligase (EC 6.3.4.3)	No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1	IJEDHG_18620	folE
GTP cyclohydrolase I (EC 3.5.4.16) type 2	No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9)	IJEDHG_12475	fmt
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5)	IJEDHG_00975	folD
Non functional Dihydropteroate synthase 2	No genes
Nucleoside triphosphate pyrophosphohydrolase MazG	No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)	IJEDHG_12100
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)	IJEDHG_22415	pabB
PqqC-like protein	No genes
Putative DHNTP pyrophosphatase	No genes
Related to Dihydropteroate synthase	No genes
Serine hydroxymethyltransferase (EC 2.1.2.1)	IJEDHG_02915
Substrate-specific component FolT of folate ECF transporter	No genes
Thymidine kinase (EC 2.7.1.21)	IJEDHG_22715
Thymidylate synthase (EC 2.1.1.45)	IJEDHG_17130	thyA
Thymidylate synthase thyX (EC 2.1.1.-)	No genes
Transaldolase (EC 2.2.1.2)	IJEDHG_03850
	IJEDHG_06280
	IJEDHG_16855	tal
Transmembrane component of general energizing module of ECF transporters	No genes
Xanthosine/inosine triphosphate pyrophosphatase	No genes
alternate gene name: yzbB	No genes