SEED Subsystem: Folate Biosynthesis in Enterobacter sp. TBS_079

Role	Gene	Name
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3)	MPMX20_00828
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	MPMX20_03770
5-nucleotidase SurE (EC 3.1.3.5)	MPMX20_03630
6-pyruvoyl tetrahydrobiopterin synthase (EC 4.2.3.12)	No genes
ATPase component of general energizing module of ECF transporters	No genes
Alternative Folylglutamate Synthase	No genes
Alternative dihydrofolate reductase 2	No genes
Alternative dihydrofolate reductase 3	No genes
Aminodeoxychorismate lyase (EC 4.1.3.38)	MPMX20_01776
COG0488: ATPase components of ABC transporters with duplicated ATPase domains	MPMX20_01600
Dihydrofolate reductase (EC 1.5.1.3)	MPMX20_00744
	MPMX20_01218
Dihydrofolate synthase (EC 6.3.2.12)	No genes
Dihydroneopterin aldolase (EC 4.1.2.25)	MPMX20_03895
Dihydroneopterin triphosphate epimerase	MPMX20_03238
Dihydroneopterin triphosphate pyrophosphohydolase	No genes
Dihydroneopterin triphosphate pyrophosphohydolase type 2	MPMX20_02770
Dihydropteroate synthase (EC 2.5.1.15)	MPMX20_04081
FolM Alternative dihydrofolate reductase 1	MPMX20_02028
Folate biosynthesis protein PTPS-III, catalyzes a reaction that bypasses dihydroneopterin aldolase (FolB)	No genes
Folate transporter 3	No genes
Folylpolyglutamate synthase (EC 6.3.2.17)	No genes
Formate--tetrahydrofolate ligase (EC 6.3.4.3)	No genes
GTP cyclohydrolase I (EC 3.5.4.16) type 1	MPMX20_03123
GTP cyclohydrolase I (EC 3.5.4.16) type 2	No genes
Methionyl-tRNA formyltransferase (EC 2.1.2.9)	MPMX20_04195
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5)	MPMX20_01107
Non functional Dihydropteroate synthase 2	No genes
Nucleoside triphosphate pyrophosphohydrolase MazG	No genes
Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)	MPMX20_04263
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)	MPMX20_02717
PqqC-like protein	No genes
Putative DHNTP pyrophosphatase	No genes
Related to Dihydropteroate synthase	No genes
Serine hydroxymethyltransferase (EC 2.1.2.1)	MPMX20_03420
Substrate-specific component FolT of folate ECF transporter	No genes
Thymidine kinase (EC 2.7.1.21)	MPMX20_02590
Thymidylate synthase (EC 2.1.1.45)	MPMX20_03690
Thymidylate synthase thyX (EC 2.1.1.-)	No genes
Transaldolase (EC 2.2.1.2)	MPMX20_00716
	MPMX20_01465
	MPMX20_03325
	MPMX20_04526
Transmembrane component of general energizing module of ECF transporters	No genes
Xanthosine/inosine triphosphate pyrophosphatase	No genes
alternate gene name: yzbB	No genes